The impact of the CACNA1C gene polymorphism on frontolimbic function in bipolar disorder.
Mol Psychiatry. 2011.
PMID: 21519340
No abstract available.
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The impact of the CACNA1C gene polymorphism or frontolimbic function in bipolar disorder
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The impact of the CACNA1C gene polymorphism on frontolimbic function in bipolar disorder.
Mol Psychiatry. 2011 Nov;16(11):1070-1. doi: 10.1038/mp.2011.49. Epub 2011 Apr 26.
Mol Psychiatry. 2011.
PMID: 21519340
No abstract available.
Impact of ZNF804A rs1344706 or CACNA1C rs1006737 polymorphisms on cognition in patients with severe mental disorders: A systematic review and meta-analysis.
World J Biol Psychiatry. 2023 Mar;24(3):195-208. doi: 10.1080/15622975.2022.2097308. Epub 2022 Jul 18.
World J Biol Psychiatry. 2023.
PMID: 35786202
OBJECTIVES: This systematic review and meta-analysis focussed on insights into the relationship between CACNA1C-rs1006737 and ZNF804A-rs1344706 polymorphisms and cognitive performance in schizophrenia (SCZ) spectrum and bipolar disorder (BD) and provide some …
OBJECTIVES: This systematic review and meta-analysis focussed on insights into the relationship between CACNA1C-rs1006737 and ZNF804A …
Neurostructural phenotypes of CACNA1C rs1006737 in adolescents with bipolar disorder and healthy controls.
Prog Neuropsychopharmacol Biol Psychiatry. 2021 Jan 10;104:110071. doi: 10.1016/j.pnpbp.2020.110071. Epub 2020 Aug 13.
Prog Neuropsychopharmacol Biol Psychiatry. 2021.
PMID: 32800865
OBJECTIVE: Investigate the effects of CACNA1C rs1006737 on cortical and subcortical neurostructural phenotypes in Caucasian bipolar disorder (BD) and healthy control (HC) adolescents. ...CONCLUSIONS: The current study identified neurostructural intermediate p …
OBJECTIVE: Investigate the effects of CACNA1C rs1006737 on cortical and subcortical neurostructural phenotypes in Caucasian bipola …
The impact of CACNA1C gene, and its epistasis with ZNF804A, on white matter microstructure in health, schizophrenia and bipolar disorder(1).
Genes Brain Behav. 2017 Apr;16(4):479-488. doi: 10.1111/gbb.12355. Epub 2016 Nov 29.
Genes Brain Behav. 2017.
PMID: 27790829
Free article.
Genome-wide studies have identified allele A (adenine) of single nucleotide polymorphism (SNP) rs1006737 of the calcium-channel CACNA1C gene as a risk factor for both schizophrenia (SZ) and bipolar disorder (BD) as well as allele A for rs1344706 …
Genome-wide studies have identified allele A (adenine) of single nucleotide polymorphism (SNP) rs1006737 of the calcium-channel CA …
Emerging biosignature of brain function and intervention in pediatric bipolar disorder.
Minerva Pediatr. 2011 Jun;63(3):183-200.
Minerva Pediatr. 2011.
PMID: 21654599
Review.
Pediatric bipolar disorder (PBD) is a complex illness with a chronic course, requiring multiple medications over the longitudinal course of illness, with limited recovery and high relapse rate. Beyond the placebo controlled trials of monotherapy, there is an increas …
Pediatric bipolar disorder (PBD) is a complex illness with a chronic course, requiring multiple medications over the longitudi …
The impact of CACNA1C allelic variation on regional gray matter volume in Chinese population.
Am J Med Genet B Neuropsychiatr Genet. 2016 Apr;171B(3):396-401. doi: 10.1002/ajmg.b.32418. Epub 2016 Jan 12.
Am J Med Genet B Neuropsychiatr Genet. 2016.
PMID: 26756527
The SNP rs1006737 in CACNA1C gene has been significantly associated with psychiatric disorders (e.g., schizophrenia and bipolar disorder) in European populations. ...Our data provides initial evidence for the involvement of this psychosis genetic …
The SNP rs1006737 in CACNA1C gene has been significantly associated with psychiatric disorders (e.g., schizophrenia and bip …
Multimodal Neuroimaging of Frontolimbic Structure and Function Associated With Suicide Attempts in Adolescents and Young Adults With Bipolar Disorder.
Am J Psychiatry. 2017 Jul 1;174(7):667-675. doi: 10.1176/appi.ajp.2016.15050652. Epub 2017 Jan 31.
Am J Psychiatry. 2017.
PMID: 28135845
Free PMC article.
This study of adolescents and young adults with bipolar disorder with and without a history of suicide attempts combines structural, diffusion tensor, and functional MR imaging methods to investigate implicated abnormalities in the morphology and structural a …
This study of adolescents and young adults with bipolar disorder with and without a history of suicide attempts combines struc …
Does the Brain Matter? Cortical Alterations in Pediatric Bipolar Disorder: A Critical Review of Structural and Functional Magnetic Resonance Studies.
Curr Neuropharmacol. 2023;21(6):1302-1318. doi: 10.2174/1570159X20666220927114417.
Curr Neuropharmacol. 2023.
PMID: 36173069
Free PMC article.
Review.
Pediatric bipolar disorder (PBD) is associated with significant psychosocial impairment, high use of mental health services and a high number of relapses and hospitalization. ...Available studies on brain connectivity in PBD patients potentially indicate less effici …
Pediatric bipolar disorder (PBD) is associated with significant psychosocial impairment, high use of mental health services an …
The impact of a CACNA1C gene polymorphism on learning and hippocampal formation in healthy individuals: a diffusion tensor imaging study.
Neuroimage. 2014 Apr 1;89:256-61. doi: 10.1016/j.neuroimage.2013.11.030. Epub 2013 Nov 21.
Neuroimage. 2014.
PMID: 24269271
BACKGROUND: Genome-wide association studies have identified the CACNA1C single nucleotide polymorphism (SNP) rs1006737 as one of the most consistent genetic findings as susceptibility locus for major psychiatric disorders. Furthermore, animal and genetic …
BACKGROUND: Genome-wide association studies have identified the CACNA1C single nucleotide polymorphism (SNP) rs1006737 as one …
Neural network of bipolar disorder: Toward integration of neuroimaging and neurocircuit-based treatment strategies.
Transl Psychiatry. 2022 Apr 5;12(1):143. doi: 10.1038/s41398-022-01917-x.
Transl Psychiatry. 2022.
PMID: 35383150
Free PMC article.
Review.
Bipolar disorder (BD) is a complex psychiatric disorder characterized by dysfunctions in three domains including emotional processing, cognitive processing, and psychomotor dimensions. ...Based on the reported data, we hypothesized that (i) the core neuropath …
Bipolar disorder (BD) is a complex psychiatric disorder characterized by dysfunctions in three domains including emotio …
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