The molecular logic of endocannabinoid signalling.
Nat Rev Neurosci. 2003.
PMID: 14595399
Review.
No abstract available.
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The molecular logic of endocannabinoid signalling.
Nat Rev Neurosci. 2003 Nov;4(11):873-84. doi: 10.1038/nrn1247.
Nat Rev Neurosci. 2003.
PMID: 14595399
Free article.
Review.
No abstract available.
Endocannabinoids in Body Weight Control.
Pharmaceuticals (Basel). 2018 May 30;11(2):55. doi: 10.3390/ph11020055.
Pharmaceuticals (Basel). 2018.
PMID: 29849009
Free PMC article.
Review.
Initially, blocking of eCB signaling by first generation cannabinoid type 1 receptor (CB1) inverse agonists such as rimonabant revealed body weight-reducing effects in laboratory animals and men. ...To finally outline the safe future potential of cannabinoids as medicines, …
Initially, blocking of eCB signaling by first generation cannabinoid type 1 receptor (CB1) inverse agonists such as rimonabant reveal …
Decoding the structural and functional diversity of GABA(A) receptors: from ensemble logic to therapeutic opportunities.
Front Pharmacol. 2025 Oct 15;16:1697905. doi: 10.3389/fphar.2025.1697905. eCollection 2025.
Front Pharmacol. 2025.
PMID: 41170380
Free PMC article.
Review.
GABA(A) receptors (GABA(A)Rs) are no longer viewed as uniform inhibitory switches but as structurally diverse, dynamically regulated ensembles that decode inhibitory signals with remarkable spatial and temporal precision. Their heterogeneity arises not only from the ninete …
GABA(A) receptors (GABA(A)Rs) are no longer viewed as uniform inhibitory switches but as structurally diverse, dynamically regulated ensembl …
At the Tip of an Iceberg: Prenatal Marijuana and Its Possible Relation to Neuropsychiatric Outcome in the Offspring.
Biol Psychiatry. 2016 Apr 1;79(7):e33-45. doi: 10.1016/j.biopsych.2015.09.009. Epub 2015 Sep 25.
Biol Psychiatry. 2016.
PMID: 26549491
Review.
By discussing the mechanisms of cannabinoid receptor-mediated signaling events at critical stages of fetal brain development, we organize histopathologic, biochemical, molecular, and behavioral findings into a logical hypothesis predicting neuronal vulnerabil …
By discussing the mechanisms of cannabinoid receptor-mediated signaling events at critical stages of fetal brain development, we orga …
Endocannabinoid receptors: CNS localization of the CB1 cannabinoid receptor.
Curr Top Behav Neurosci. 2009;1:65-86. doi: 10.1007/978-3-540-88955-7_3.
Curr Top Behav Neurosci. 2009.
PMID: 21104380
The evolution of plant metabolic pathways to invent compounds which distract predators, and the history of medicine to find treatments for diseases, often share a common logic. An attractive example to illustrate the rationale behind this is the Cannabis sativa plant, whic …
The evolution of plant metabolic pathways to invent compounds which distract predators, and the history of medicine to find treatments for d …
Use of Cannabidiol (CBD) oil in the treatment of PTSD: Study design and rationale for a placebo-controlled randomized clinical trial.
Contemp Clin Trials. 2022 Nov;122:106933. doi: 10.1016/j.cct.2022.106933. Epub 2022 Sep 22.
Contemp Clin Trials. 2022.
PMID: 36154908
Clinical Trial.
Recently, there's been considerable attention paid to the potential therapeutic use of cannabidiol (CBD) products in the treatment of a variety of physical and mental health problems. The endocannabinoid system (ECS) is a logical therapeutic target for combating PTS …
Recently, there's been considerable attention paid to the potential therapeutic use of cannabidiol (CBD) products in the treatment of a vari …
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