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The teratogenic metabolites of vitamin A in women following supplements and liver.
Buss NE, Tembe EA, Prendergast BD, Renwick AG, George CF. Buss NE, et al. Hum Exp Toxicol. 1994 Jan;13(1):33-43. doi: 10.1177/096032719401300106. Hum Exp Toxicol. 1994. PMID: 8198828
The peak plasma concentrations (Cmax) of all-transretinoic acid, the principal teratogenic metabolite of retinol, and the area under the concentration-time curve (AUC) were up to 20-times higher after supplements compared to the same dose as liver. ... …
The peak plasma concentrations (Cmax) of all-transretinoic acid, the principal teratogenic metabolite of retinol, and the area …
Exposure to retinoic acids in non-pregnant women following high vitamin A intake with a liver meal.
Hartmann S, Brørs O, Bock J, Blomhoff R, Bausch J, Wiegand UW, Hartmann D, Hornig DH. Hartmann S, et al. Int J Vitam Nutr Res. 2005 May;75(3):187-94. doi: 10.1024/0300-9831.75.3.187. Int J Vitam Nutr Res. 2005. PMID: 16028634 Clinical Trial.
Animal liver is a rich source of vitamin A. Due to retinoic acid (RA) metabolites, vitamin A has a teratogenic potential and women are generally advised to avoid or to limit the consumption of liver during pregnancy. In a recent st …
Animal liver is a rich source of vitamin A. Due to retinoic acid (RA) metabolites, vitamin A has a teratogeni
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