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SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues.
Ziegler CGK, Allon SJ, Nyquist SK, Mbano IM, Miao VN, Tzouanas CN, Cao Y, Yousif AS, Bals J, Hauser BM, Feldman J, Muus C, Wadsworth MH 2nd, Kazer SW, Hughes TK, Doran B, Gatter GJ, Vukovic M, Taliaferro F, Mead BE, Guo Z, Wang JP, Gras D, Plaisant M, Ansari M, Angelidis I, Adler H, Sucre JMS, Taylor CJ, Lin B, Waghray A, Mitsialis V, Dwyer DF, Buchheit KM, Boyce JA, Barrett NA, Laidlaw TM, Carroll SL, Colonna L, Tkachev V, Peterson CW, Yu A, Zheng HB, Gideon HP, Winchell CG, Lin PL, Bingle CD, Snapper SB, Kropski JA, Theis FJ, Schiller HB, Zaragosi LE, Barbry P, Leslie A, Kiem HP, Flynn JL, Fortune SM, Berger B, Finberg RW, Kean LS, Garber M, Schmidt AG, Lingwood D, Shalek AK, Ordovas-Montanes J; HCA Lung Biological Network. Electronic address: lung-network@humancellatlas.org; HCA Lung Biological Network. Ziegler CGK, et al. Among authors: Theis FJ. Cell. 2020 Apr 27:S0092-8674(20)30500-6. doi: 10.1016/j.cell.2020.04.035. Online ahead of print. Cell. 2020. PMID: 32413319 Free article.
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes.
Sungnak W, Huang N, Bécavin C, Berg M, Queen R, Litvinukova M, Talavera-López C, Maatz H, Reichart D, Sampaziotis F, Worlock KB, Yoshida M, Barnes JL; HCA Lung Biological Network. Sungnak W, et al. Nat Med. 2020 May;26(5):681-687. doi: 10.1038/s41591-020-0868-6. Epub 2020 Apr 23. Nat Med. 2020. PMID: 32327758
The single-cell eQTLGen consortium.
van der Wijst M, de Vries DH, Groot HE, Trynka G, Hon CC, Bonder MJ, Stegle O, Nawijn MC, Idaghdour Y, van der Harst P, Ye CJ, Powell J, Theis FJ, Mahfouz A, Heinig M, Franke L. van der Wijst M, et al. Among authors: Theis FJ. Elife. 2020 Mar 9;9:e52155. doi: 10.7554/eLife.52155. Elife. 2020. PMID: 32149610 Free PMC article.
Model-based analysis of response and resistance factors of cetuximab treatment in gastric cancer cell lines.
Raimúndez E, Keller S, Zwingenberger G, Ebert K, Hug S, Theis FJ, Maier D, Luber B, Hasenauer J. Raimúndez E, et al. Among authors: Theis FJ. PLoS Comput Biol. 2020 Mar 2;16(3):e1007147. doi: 10.1371/journal.pcbi.1007147. eCollection 2020 Mar. PLoS Comput Biol. 2020. PMID: 32119655 Free PMC article.
Epithelial Planar Bipolarity Emerges from Notch-Mediated Asymmetric Inhibition of Emx2.
Kozak EL, Palit S, Miranda-Rodríguez JR, Janjic A, Böttcher A, Lickert H, Enard W, Theis FJ, López-Schier H. Kozak EL, et al. Among authors: Theis FJ. Curr Biol. 2020 Mar 23;30(6):1142-1151.e6. doi: 10.1016/j.cub.2020.01.027. Epub 2020 Feb 27. Curr Biol. 2020. PMID: 32109392
Eleven grand challenges in single-cell data science.
Lähnemann D, Köster J, Szczurek E, McCarthy DJ, Hicks SC, Robinson MD, Vallejos CA, Campbell KR, Beerenwinkel N, Mahfouz A, Pinello L, Skums P, Stamatakis A, Attolini CS, Aparicio S, Baaijens J, Balvert M, Barbanson B, Cappuccio A, Corleone G, Dutilh BE, Florescu M, Guryev V, Holmer R, Jahn K, Lobo TJ, Keizer EM, Khatri I, Kielbasa SM, Korbel JO, Kozlov AM, Kuo TH, Lelieveldt BPF, Mandoiu II, Marioni JC, Marschall T, Mölder F, Niknejad A, Raczkowski L, Reinders M, Ridder J, Saliba AE, Somarakis A, Stegle O, Theis FJ, Yang H, Zelikovsky A, McHardy AC, Raphael BJ, Shah SP, Schönhuth A. Lähnemann D, et al. Among authors: Theis FJ. Genome Biol. 2020 Feb 7;21(1):31. doi: 10.1186/s13059-020-1926-6. Genome Biol. 2020. PMID: 32033589 Free PMC article. Review.
DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning.
Arloth J, Eraslan G, Andlauer TFM, Martins J, Iurato S, Kühnel B, Waldenberger M, Frank J, Gold R, Hemmer B, Luessi F, Nischwitz S, Paul F, Wiendl H, Gieger C, Heilmann-Heimbach S, Kacprowski T, Laudes M, Meitinger T, Peters A, Rawal R, Strauch K, Lucae S, Müller-Myhsok B, Rietschel M, Theis FJ, Binder EB, Mueller NS. Arloth J, et al. Among authors: Theis FJ. PLoS Comput Biol. 2020 Feb 3;16(2):e1007616. doi: 10.1371/journal.pcbi.1007616. eCollection 2020 Feb. PLoS Comput Biol. 2020. PMID: 32012148 Free PMC article.
IL-17C amplifies epithelial inflammation in human psoriasis and atopic eczema.
Lauffer F, Jargosch M, Baghin V, Krause L, Kempf W, Absmaier-Kijak M, Morelli M, Madonna S, Marsais F, Lepescheux L, Albanesi C, Müller NS, Theis FJ, Schmidt-Weber C, Eyerich S, Biedermann T, Vandeghinste N, Steidl S, Eyerich K. Lauffer F, et al. Among authors: Theis FJ. J Eur Acad Dermatol Venereol. 2020 Apr;34(4):800-809. doi: 10.1111/jdv.16126. Epub 2020 Jan 19. J Eur Acad Dermatol Venereol. 2020. PMID: 31793105
Corrigendum: Is the humoral immunity dispensable for the pathogenesis of psoriasis?
Thomas J, Küpper M, Batra R, Jargosch M, Atenhan A, Baghin V, Krause L, Lauffer F, Biedermann T, Theis FJ, Eyerich K, Schmidt-Weber CB, Eyerich S, Garzorz-Stark N. Thomas J, et al. Among authors: Theis FJ. J Eur Acad Dermatol Venereol. 2019 Dec;33(12):2380. doi: 10.1111/jdv.16019. J Eur Acad Dermatol Venereol. 2019. PMID: 31779039 No abstract available.
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