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A functional cancer genomics screen identifies a druggable synthetic lethal interaction between MSH3 and PRKDC.
Dietlein F, Thelen L, Jokic M, Jachimowicz RD, Ivan L, Knittel G, Leeser U, van Oers J, Edelmann W, Heukamp LC, Reinhardt HC. Dietlein F, et al. Among authors: thelen l. Cancer Discov. 2014 May;4(5):592-605. doi: 10.1158/2159-8290.CD-13-0907. Epub 2014 Feb 20. Cancer Discov. 2014. PMID: 24556366 Free article.
Label-Free Protein-RNA Interactome Analysis Identifies Khsrp Signaling Downstream of the p38/Mk2 Kinase Complex as a Critical Modulator of Cell Cycle Progression.
Boucas J, Fritz C, Schmitt A, Riabinska A, Thelen L, Peifer M, Leeser U, Nuernberg P, Altmueller J, Gaestel M, Dieterich C, Reinhardt HC. Boucas J, et al. Among authors: thelen l. PLoS One. 2015 May 20;10(5):e0125745. doi: 10.1371/journal.pone.0125745. eCollection 2015. PLoS One. 2015. PMID: 25993413 Free PMC article.
Meta-Analysis Reveals Significant Sex Differences in Chronic Lymphocytic Leukemia Progression in the Eµ-TCL1 Transgenic Mouse Model.
Koch M, Reinartz S, Saggau J, Knittel G, Rosen N, Fedorchenko O, Thelen L, Barthel R, Reinart N, Seeger-Nukpezah T, Reinhardt HC, Hallek M, Nguyen PH. Koch M, et al. Among authors: thelen l. Cancers (Basel). 2020 Jul 20;12(7):E1980. doi: 10.3390/cancers12071980. Cancers (Basel). 2020. PMID: 32698538 Free article.
Teleocidin A2 inhibits human proteinase-activated receptor 2 signaling in tumor cells.
Stahn S, Thelen L, Albrecht IM, Bitzer J, Henkel T, Teusch NE. Stahn S, et al. Among authors: thelen l. Pharmacol Res Perspect. 2016 Jun 10;4(4):e00230. doi: 10.1002/prp2.230. eCollection 2016 Aug. Pharmacol Res Perspect. 2016. PMID: 28116092 Free PMC article.
Endobronchial ultrasonography versus mediastinoscopy: a single-institution cost analysis and waste comparison.
Andrade RS, Podgaetz E, Rueth NM, Majumder K, Hall E, Saric C, Thelen L. Andrade RS, et al. Among authors: thelen l. Ann Thorac Surg. 2014 Sep;98(3):1003-7. doi: 10.1016/j.athoracsur.2014.04.104. Epub 2014 Jul 16. Ann Thorac Surg. 2014. PMID: 25038020
The Escherichia coli ribosomal RNA leader: a structural and functional investigation.
Pardon B, Thelen L, Wagner R. Pardon B, et al. Among authors: thelen l. Biol Chem Hoppe Seyler. 1994 Jan;375(1):11-20. doi: 10.1515/bchm3.1994.375.1.11. Biol Chem Hoppe Seyler. 1994. PMID: 7516168
Some base substitutions in the leader of an Escherichia coli ribosomal RNA operon affect the structure and function of ribosomes. Evidence for a transient scaffold function of the rRNA leader.
Theissen G, Thelen L, Wagner R. Theissen G, et al. Among authors: thelen l. J Mol Biol. 1993 Sep 20;233(2):203-18. doi: 10.1006/jmbi.1993.1500. J Mol Biol. 1993. PMID: 8377198