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Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation.
Cuello F, Knaust AE, Saleem U, Loos M, Raabe J, Mosqueira D, Laufer S, Schweizer M, van der Kraak P, Flenner F, Ulmer BM, Braren I, Yin X, Theofilatos K, Ruiz-Orera J, Patone G, Klampe B, Schulze T, Piasecki A, Pinto Y, Vink A, Hübner N, Harding S, Mayr M, Denning C, Eschenhagen T, Hansen A. Cuello F, et al. Among authors: theofilatos k. EMBO Mol Med. 2021 Jun 7;13(6):e13074. doi: 10.15252/emmm.202013074. Epub 2021 May 16. EMBO Mol Med. 2021. PMID: 33998164 Free PMC article.
Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia.
Moreira LM, Takawale A, Hulsurkar M, Menassa DA, Antanaviciute A, Lahiri SK, Mehta N, Evans N, Psarros C, Robinson P, Sparrow AJ, Gillis MA, Ashley N, Naud P, Barallobre-Barreiro J, Theofilatos K, Lee A, Norris M, Clarke MV, Russell PK, Casadei B, Bhattacharya S, Zajac JD, Davey RA, Sirois M, Mead A, Simmons A, Mayr M, Sayeed R, Krasopoulos G, Redwood C, Channon KM, Tardif JC, Wehrens XHT, Nattel S, Reilly S. Moreira LM, et al. Among authors: theofilatos k. Nature. 2020 Nov;587(7834):460-465. doi: 10.1038/s41586-020-2890-8. Epub 2020 Nov 4. Nature. 2020. PMID: 33149301
Systems biology in cardiovascular disease: a multiomics approach.
Joshi A, Rienks M, Theofilatos K, Mayr M. Joshi A, et al. Among authors: theofilatos k. Nat Rev Cardiol. 2021 May;18(5):313-330. doi: 10.1038/s41569-020-00477-1. Epub 2020 Dec 18. Nat Rev Cardiol. 2021. PMID: 33340009 Review.
SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care.
Gutmann C, Takov K, Burnap SA, Singh B, Ali H, Theofilatos K, Reed E, Hasman M, Nabeebaccus A, Fish M, McPhail MJ, O'Gallagher K, Schmidt LE, Cassel C, Rienks M, Yin X, Auzinger G, Napoli S, Mujib SF, Trovato F, Sanderson B, Merrick B, Niazi U, Saqi M, Dimitrakopoulou K, Fernández-Leiro R, Braun S, Kronstein-Wiedemann R, Doores KJ, Edgeworth JD, Shah AM, Bornstein SR, Tonn T, Hayday AC, Giacca M, Shankar-Hari M, Mayr M. Gutmann C, et al. Among authors: theofilatos k. Nat Commun. 2021 Jun 7;12(1):3406. doi: 10.1038/s41467-021-23494-1. Nat Commun. 2021. PMID: 34099652 Free PMC article.
Protein Aggregation Is an Early Manifestation of Phospholamban p.(Arg14del)-Related Cardiomyopathy: Development of PLN-R14del-Related Cardiomyopathy.
Eijgenraam TR, Boogerd CJ, Stege NM, Oliveira Nunes Teixeira V, Dokter MM, Schmidt LE, Yin X, Theofilatos K, Mayr M, van der Meer P, van Rooij E, van der Velden J, Silljé HHW, de Boer RA. Eijgenraam TR, et al. Among authors: theofilatos k. Circ Heart Fail. 2021 Nov;14(11):e008532. doi: 10.1161/CIRCHEARTFAILURE.121.008532. Epub 2021 Sep 30. Circ Heart Fail. 2021. PMID: 34587756 Free PMC article.
Extracellular Matrix in Heart Failure: Role of ADAMTS5 in Proteoglycan Remodeling.
Barallobre-Barreiro J, Radovits T, Fava M, Mayr U, Lin WY, Ermolaeva E, Martínez-López D, Lindberg EL, Duregotti E, Daróczi L, Hasman M, Schmidt LE, Singh B, Lu R, Baig F, Siedlar AM, Cuello F, Catibog N, Theofilatos K, Shah AM, Crespo-Leiro MG, Doménech N, Hübner N, Merkely B, Mayr M. Barallobre-Barreiro J, et al. Among authors: theofilatos k. Circulation. 2021 Dec 21;144(25):2021-2034. doi: 10.1161/CIRCULATIONAHA.121.055732. Epub 2021 Nov 22. Circulation. 2021. PMID: 34806902 Free PMC article.
Gene editing reverses arrhythmia susceptibility in humanized PLN-R14del mice: modelling a European cardiomyopathy with global impact.
Dave J, Raad N, Mittal N, Zhang L, Fargnoli A, Oh JG, Savoia ME, Hansen J, Fava M, Yin X, Theofilatos K, Ceholski D, Kohlbrenner E, Jeong D, Wills L, Nonnenmacher M, Haghighi K, Costa KD, Turnbull IC, Mayr M, Cai CL, Kranias EG, Akar FG, Hajjar RJ, Stillitano F. Dave J, et al. Among authors: theofilatos k. Cardiovasc Res. 2022 Dec 9;118(15):3140-3150. doi: 10.1093/cvr/cvac021. Cardiovasc Res. 2022. PMID: 35191471 Free PMC article.
Uncovering Protein Networks in Cardiovascular Proteomics.
Hasman M, Mayr M, Theofilatos K. Hasman M, et al. Among authors: theofilatos k. Mol Cell Proteomics. 2023 Aug;22(8):100607. doi: 10.1016/j.mcpro.2023.100607. Epub 2023 Jun 24. Mol Cell Proteomics. 2023. PMID: 37356494 Free PMC article. Review.
SERCA2a Protein Levels Are Unaltered in Human Heart Failure.
Ragone I, Barallobre-Barreiro J, Takov K, Theofilatos K, Yin X, Schmidt LE, Domenech N, Crespo-Leiro MG, van der Voorn SM, Vink A, van Veen TAB, Bödör C, Merkely B, Radovits T, Mayr M. Ragone I, et al. Among authors: theofilatos k. Circulation. 2023 Aug 15;148(7):613-616. doi: 10.1161/CIRCULATIONAHA.123.064513. Epub 2023 Aug 14. Circulation. 2023. PMID: 37579008 Free PMC article. No abstract available.
339 results