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The multiple pathways to autoimmunity.
Theofilopoulos AN, Kono DH, Baccala R. Theofilopoulos AN, et al. Nat Immunol. 2017 Jun 20;18(7):716-724. doi: 10.1038/ni.3731. Nat Immunol. 2017. PMID: 28632714 Free PMC article. Review.
Induction of Systemic Autoimmunity by a Xenobiotic Requires Endosomal TLR Trafficking and Signaling from the Late Endosome and Endolysosome but Not Type I IFN.
Pollard KM, Escalante GM, Huang H, Haraldsson KM, Hultman P, Christy JM, Pawar RD, Mayeux JM, Gonzalez-Quintial R, Baccala R, Beutler B, Theofilopoulos AN, Kono DH. Pollard KM, et al. Among authors: theofilopoulos an. J Immunol. 2017 Dec 1;199(11):3739-3747. doi: 10.4049/jimmunol.1700332. Epub 2017 Oct 20. J Immunol. 2017. PMID: 29055005 Free PMC article.
Interleukin-7 is required for CD4(+) T cell activation and autoimmune neuroinflammation.
Lawson BR, Gonzalez-Quintial R, Eleftheriadis T, Farrar MA, Miller SD, Sauer K, McGavern DB, Kono DH, Baccala R, Theofilopoulos AN. Lawson BR, et al. Among authors: theofilopoulos an. Clin Immunol. 2015 Dec;161(2):260-9. doi: 10.1016/j.clim.2015.08.007. Epub 2015 Aug 25. Clin Immunol. 2015. PMID: 26319414 Free PMC article.
Type I interferon is a therapeutic target for virus-induced lethal vascular damage.
Baccala R, Welch MJ, Gonzalez-Quintial R, Walsh KB, Teijaro JR, Nguyen A, Ng CT, Sullivan BM, Zarpellon A, Ruggeri ZM, de la Torre JC, Theofilopoulos AN, Oldstone MB. Baccala R, et al. Among authors: theofilopoulos an. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8925-30. doi: 10.1073/pnas.1408148111. Epub 2014 Jun 2. Proc Natl Acad Sci U S A. 2014. PMID: 24889626 Free PMC article.
An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence.
Berger M, Krebs P, Crozat K, Li X, Croker BA, Siggs OM, Popkin D, Du X, Lawson BR, Theofilopoulos AN, Xia Y, Khovananth K, Moresco EM, Satoh T, Takeuchi O, Akira S, Beutler B. Berger M, et al. Among authors: theofilopoulos an. Nat Immunol. 2010 Apr;11(4):335-43. doi: 10.1038/ni.1847. Epub 2010 Feb 28. Nat Immunol. 2010. PMID: 20190759 Free PMC article.
258 results