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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 1
1970 1
1972 1
1973 1
1975 1
1976 3
1977 2
1978 2
1979 1
1981 5
1982 2
1983 3
1984 3
1985 4
1986 4
1987 2
1988 3
1989 3
1990 2
1992 4
1993 2
1994 1
1995 3
1996 2
1997 2
1998 3
1999 1
2000 5
2001 1
2002 7
2003 3
2004 1
2005 7
2006 4
2007 2
2008 2
2009 2
2010 6
2011 2
2012 12
2013 7
2014 4
2015 3
2016 6
2017 9
2018 6
2019 5
2020 10
2021 6
2022 18
2023 17
2024 13
2025 6

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204 results

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Page 1
Mechanisms of action of vitamin B1 (thiamine), B6 (pyridoxine), and B12 (cobalamin) in pain: a narrative review.
Paez-Hurtado AM, Calderon-Ospina CA, Nava-Mesa MO. Paez-Hurtado AM, et al. Nutr Neurosci. 2023 Mar;26(3):235-253. doi: 10.1080/1028415X.2022.2034242. Epub 2022 Feb 14. Nutr Neurosci. 2023. PMID: 35156556 Review.
New evidence suggests their therapeutic potential in different pain conditions. In this review, we discuss the main role of neurotropic B vitamins on different nociceptive pathways in the nervous system and to describe their analgesic action mechanisms. ...Some of t …
New evidence suggests their therapeutic potential in different pain conditions. In this review, we discuss the main role of ne …
Treatment of Refractory Convulsive Status Epilepticus: A Comprehensive Review by the American Epilepsy Society Treatments Committee.
Vossler DG, Bainbridge JL, Boggs JG, Novotny EJ, Loddenkemper T, Faught E, Amengual-Gual M, Fischer SN, Gloss DS, Olson DM, Towne AR, Naritoku D, Welty TE. Vossler DG, et al. Epilepsy Curr. 2020 Sep;20(5):245-264. doi: 10.1177/1535759720928269. Epub 2020 Aug 21. Epilepsy Curr. 2020. PMID: 32822230 Free PMC article.
For adults with CRSE, insufficient evidence exists to support the effectiveness of LEV (level U; 2 class IV studies). Magnesium sulfate may be effective in the treatment of eclampsia, but there are only case reports of its use for CRSE. ...Triple-masked, randomiz
For adults with CRSE, insufficient evidence exists to support the effectiveness of LEV (level U; 2 class IV studies). Magnesium sulfa …
The effects of pyridoxine (vitamin B6) supplementation in nausea and vomiting during pregnancy: a systematic review and meta-analysis.
Jayawardena R, Majeed S, Sooriyaarachchi P, Abeywarne U, Ranaweera P. Jayawardena R, et al. Arch Gynecol Obstet. 2023 Oct;308(4):1075-1084. doi: 10.1007/s00404-023-06925-w. Epub 2023 Jan 31. Arch Gynecol Obstet. 2023. PMID: 36719452 Review.
Eight studies showed beneficial effects with pyridoxine alone as the supplementation, while six others found that the supplementation of pyridoxine in combination with another active substance had favourable effects. ...CONCLUSION: Supplementation of …
Eight studies showed beneficial effects with pyridoxine alone as the supplementation, while six others found that the suppleme …
Acupuncture and Doxylamine-Pyridoxine for Nausea and Vomiting in Pregnancy : A Randomized, Controlled, 2 2 Factorial Trial.
Wu XK, Gao JS, Ma HL, Wang Y, Zhang B, Liu ZL, Li J, Cong J, Qin HC, Yang XM, Wu Q, Chen XY, Lu ZL, Feng YH, Qi X, Wang YX, Yu L, Cui YM, An CM, Zhou LL, Hu YH, Li L, Cao YJ, Yan Y, Liu L, Liu YX, Liu ZS, Painter RC, Ng EHY, Liu JP, Mol BWJ, Wang CC. Wu XK, et al. Ann Intern Med. 2023 Jul;176(7):922-933. doi: 10.7326/M22-2974. Epub 2023 Jun 20. Ann Intern Med. 2023. PMID: 37335994 Clinical Trial.
DESIGN: Multicenter, randomized, double-blind, placebo-controlled, 2 2 factorial trial. (ClinicalTrials.gov: NCT04401384). ...CONCLUSION: Both acupuncture and doxylamine-pyridoxine alone are efficacious for moderate and severe NVP. However, the clinical impor …
DESIGN: Multicenter, randomized, double-blind, placebo-controlled, 2 2 factorial trial. (ClinicalTrials.gov: NCT04401384). ... …
Vitamin neurotoxicity.
Snodgrass SR. Snodgrass SR. Mol Neurobiol. 1992 Spring;6(1):41-73. doi: 10.1007/BF02935566. Mol Neurobiol. 1992. PMID: 1463588 Review.
The only well-established human vitamin neurotoxic effects are those due to hypervitaminosis A (pseudotumor cerebri) and pyridoxine (sensory neuropathy). ...Folates and thiamine cause seizures and excitation when administered in high dosage directly into the brain o …
The only well-established human vitamin neurotoxic effects are those due to hypervitaminosis A (pseudotumor cerebri) and pyridoxin
Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial.
Pouteau E, Kabir-Ahmadi M, Noah L, Mazur A, Dye L, Hellhammer J, Pickering G, Dubray C. Pouteau E, et al. PLoS One. 2018 Dec 18;13(12):e0208454. doi: 10.1371/journal.pone.0208454. eCollection 2018. PLoS One. 2018. PMID: 30562392 Free PMC article. Clinical Trial.
INTRODUCTION: Animal and clinical studies suggest complementary effects of magnesium and high-dose pyridoxine (vitamin B6) on stress reduction. This is the first randomized trial evaluating the effects of combined magnesium and vitamin B6 supplementati …
INTRODUCTION: Animal and clinical studies suggest complementary effects of magnesium and high-dose pyridoxine (vitamin B6) on …
Toxic neuropathy.
Umapathi T, Chaudhry V. Umapathi T, et al. Curr Opin Neurol. 2005 Oct;18(5):574-80. doi: 10.1097/01.wco.0000180158.34713.aa. Curr Opin Neurol. 2005. PMID: 16155443 Review.
PURPOSE OF REVIEW: This paper examines recent research on toxic neuropathy and potential therapeutic developments. It also summarizes reports of new agents reported to cause peripheral neuropathy. ...Cisplatin and high-dose pyridoxine are used more frequently …
PURPOSE OF REVIEW: This paper examines recent research on toxic neuropathy and potential therapeutic developments. It also sum …
Preserving mitochondrial homeostasis protects against drug-induced liver injury via inducing OPTN (optineurin)-dependent Mitophagy.
Wang J, Qiu Y, Yang L, Wang J, He J, Tang C, Yang Z, Hong W, Yang B, He Q, Weng Q. Wang J, et al. Autophagy. 2024 Dec;20(12):2677-2696. doi: 10.1080/15548627.2024.2384348. Epub 2024 Aug 4. Autophagy. 2024. PMID: 39099169
Then, the accumulation of OPTN in different DILIs is further validated with a protective effect, and pyridoxine is screened and established to alleviate DILIs by inducing OPTN-mediated mitophagy. Collectively, our findings uncover a dual role of OPTN in mitophagy in …
Then, the accumulation of OPTN in different DILIs is further validated with a protective effect, and pyridoxine is screened an …
Natural product P57 induces hypothermia through targeting pyridoxal kinase.
Wang R, Xiao L, Pan J, Bao G, Zhu Y, Zhu D, Wang J, Pei C, Ma Q, Fu X, Wang Z, Zhu M, Wang G, Gong L, Tong Q, Jiang M, Hu J, He M, Wang Y, Li T, Liang C, Li W, Xia C, Li Z, Ma DK, Tan M, Liu JY, Jiang W, Luo C, Yu B, Dang Y. Wang R, et al. Nat Commun. 2023 Sep 26;14(1):5984. doi: 10.1038/s41467-023-41435-y. Nat Commun. 2023. PMID: 37752106 Free PMC article.
We further found that P57 and PL have consistent effects on gene expression regulation in hypothalamus, and they may activate medial preoptic area (MPA) neurons in POA to induce hypothermia. Taken together, our findings demonstrate that P57 has a potential applicati …
We further found that P57 and PL have consistent effects on gene expression regulation in hypothalamus, and they may activate medial …
204 results