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1963 2
1964 3
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1970 7
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1975 38
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1984 47
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1986 48
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1989 47
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2009 354
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2011 387
2012 416
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11,412 results

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Page 1
Did you mean hemodynamic principles (6,328 results)?
Science of, and insights into, thermodynamic principles for dermal formulations.
Tapfumaneyi P, Imran M, Alavi SE, Mohammed Y. Tapfumaneyi P, et al. Drug Discov Today. 2023 Apr;28(4):103521. doi: 10.1016/j.drudis.2023.103521. Epub 2023 Feb 6. Drug Discov Today. 2023. PMID: 36754143 Review.
It can be changed according to the physicochemical parameters (e.g., solubility, partition coefficient, and water activity) of the drug in the vehicle. Thermodynamic principles have been used for the development of novel topical and transdermal delivery systems, dem …
It can be changed according to the physicochemical parameters (e.g., solubility, partition coefficient, and water activity) of the drug in t …
Energetic profiling reveals thermodynamic principles underlying amyloid fibril maturation.
Duran-Romaña R, Schymkowitz J, Rousseau F, Louros N. Duran-Romaña R, et al. Nat Commun. 2025 Nov 18;16(1):10081. doi: 10.1038/s41467-025-65035-0. Nat Commun. 2025. PMID: 41253764 Free PMC article.
Amyloid fibrils adopt diverse structural polymorphs linked to disease-specific phenotypes, but the thermodynamic principles guiding their formation and maturation remain unclear. Here, we apply energetic profiling to structural time series from cryo-EM datasets of I …
Amyloid fibrils adopt diverse structural polymorphs linked to disease-specific phenotypes, but the thermodynamic principles gu …
Engineering microbial communities using thermodynamic principles and electrical interfaces.
Zerfaß C, Chen J, Soyer OS. Zerfaß C, et al. Curr Opin Biotechnol. 2018 Apr;50:121-127. doi: 10.1016/j.copbio.2017.12.004. Epub 2017 Dec 18. Curr Opin Biotechnol. 2018. PMID: 29268107 Free article. Review.
These are expected to generate higher-level thermodynamic bounds onto the system, which the community structure and function can then adapt to. ...Toward designing the exact nature of the environmental enforcement, thermodynamics and redox biochemistry can act as co …
These are expected to generate higher-level thermodynamic bounds onto the system, which the community structure and function can then …
Thermodynamic principles for system biology and the patterns of flower pigmentation.
Zhao Q. Zhao Q. Theory Biosci. 2022 Sep;141(3):273-278. doi: 10.1007/s12064-022-00372-y. Epub 2022 Jul 20. Theory Biosci. 2022. PMID: 35857270
The thermodynamic principles for system biology are reviewed and formulated, and then basic patterns of flower pigmentation are interpreted. ...In this theory, the dominant inheritance means that a gene contributes great to the thermodynamic stability of a tr …
The thermodynamic principles for system biology are reviewed and formulated, and then basic patterns of flower pigmentation ar …
Exchange factors, effectors, GAPs and motor proteins: common thermodynamic and kinetic principles for different functions.
Goody RS, Hofmann-Goody W. Goody RS, et al. Eur Biophys J. 2002 Jul;31(4):268-74. doi: 10.1007/s00249-002-0225-3. Epub 2002 Jun 21. Eur Biophys J. 2002. PMID: 12122473 Review.
In this article, we review the properties of several classes of proteins that interact with ATPases and GTPases involved in energy and signal transduction. We show that certain common basic thermodynamic principles apply to the manner in which the nucleotide hydrola …
In this article, we review the properties of several classes of proteins that interact with ATPases and GTPases involved in energy and signa …
The application of thermodynamic principles to histochemical and morphometric tissue research: principles and practical outline with focus on the glycosciences.
Kayser K, Gabius HJ. Kayser K, et al. Cell Tissue Res. 1999 Jun;296(3):443-55. doi: 10.1007/s004410051305. Cell Tissue Res. 1999. PMID: 10370131 Review.
Since organisms or their compartments are thermodynamically open systems, they are insufficiently described by the (structural) entropy. ...Since biochemical factors will contribute to the generation and establishment of these structural and thermodynamic features a …
Since organisms or their compartments are thermodynamically open systems, they are insufficiently described by the (structural) entro …
Thermodynamic Principles for the Design of Polymers for Drug Formulations.
Fischlschweiger M, Enders S. Fischlschweiger M, et al. Annu Rev Chem Biomol Eng. 2019 Jun 7;10:311-335. doi: 10.1146/annurev-chembioeng-060718-030304. Epub 2019 Mar 22. Annu Rev Chem Biomol Eng. 2019. PMID: 30901257
Among the latter, formulation approaches that lead to prolonged drug supersaturation to maximize the driving force for sustained intestinal absorption of an oral product, or to allow sufficient time for injection after reconstitution of a parenteral lyophile formulation, have att …
Among the latter, formulation approaches that lead to prolonged drug supersaturation to maximize the driving force for sustained intestinal …
Protein thermodynamic structure.
Zhao Q. Zhao Q. IUBMB Life. 2009 Jun;61(6):600-6. doi: 10.1002/iub.214. IUBMB Life. 2009. PMID: 19472177 Free article. Review.
In this article, we show that much of our present knowledge of protein science is explainable by principles of protein thermodynamic structure theory. A deductive system for protein knowledge has been developed and several fundamental questions of protein science ca …
In this article, we show that much of our present knowledge of protein science is explainable by principles of protein thermodynam …
Modeling a propionate-oxidizing syntrophic coculture using thermodynamic principles.
Leurent A, Moscoviz R. Leurent A, et al. Biotechnol Bioeng. 2022 Sep;119(9):2423-2436. doi: 10.1002/bit.28156. Epub 2022 Jun 21. Biotechnol Bioeng. 2022. PMID: 35680641
When applied to the test data set it systematically resulted in positive Gibbs free energy changes values for propionate oxidation, in contradiction with the second law of thermodynamics. On the opposite, the parameters fitted with model including both a thermodynamic …
When applied to the test data set it systematically resulted in positive Gibbs free energy changes values for propionate oxidation, in contr …
Thermodynamics of Bioreactions.
Held C, Sadowski G. Held C, et al. Annu Rev Chem Biomol Eng. 2016 Jun 7;7:395-414. doi: 10.1146/annurev-chembioeng-080615-034704. Annu Rev Chem Biomol Eng. 2016. PMID: 27276551 Review.
Thermodynamic principles have been applied to enzyme-catalyzed reactions since the beginning of the 1930s in an attempt to understand metabolic pathways. Currently, thermodynamics is also applied to the design and analysis of biotechnological processes. The k …
Thermodynamic principles have been applied to enzyme-catalyzed reactions since the beginning of the 1930s in an attempt to und …
11,412 results
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