Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

163 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
Synthesis and characterization of the colistin peptide polymyxin E1 and related antimicrobial peptides.
Kline T, Holub D, Therrien J, Leung T, Ryckman D. Kline T, et al. Among authors: therrien j. J Pept Res. 2001 Mar;57(3):175-87. doi: 10.1111/j.1399-3011.2001.00835.x. J Pept Res. 2001. PMID: 11298918
A prodrug approach toward the development of water soluble fluoroquinolones and structure--activity relationships of quinoline-3-carboxylic acids.
Baker WR, Cai S, Dimitroff M, Fang L, Huh KK, Ryckman DR, Shang X, Shawar RM, Therrien JH. Baker WR, et al. J Med Chem. 2004 Sep 9;47(19):4693-709. doi: 10.1021/jm0497895. J Med Chem. 2004. PMID: 15341485
Atropisomerism by Design: Discovery of a Selective and Stable Phosphoinositide 3-Kinase (PI3K) β Inhibitor.
Chandrasekhar J, Dick R, Van Veldhuizen J, Koditek D, Lepist EI, McGrath ME, Patel L, Phillips G, Sedillo K, Somoza JR, Therrien J, Till NA, Treiberg J, Villaseñor AG, Zherebina Y, Perreault S. Chandrasekhar J, et al. Among authors: therrien j. J Med Chem. 2018 Aug 9;61(15):6858-6868. doi: 10.1021/acs.jmedchem.8b00797. Epub 2018 Jul 30. J Med Chem. 2018. PMID: 30015489
Discovery of a Phosphoinositide 3-Kinase (PI3K) β/δ Inhibitor for the Treatment of Phosphatase and Tensin Homolog (PTEN) Deficient Tumors: Building PI3Kβ Potency in a PI3Kδ-Selective Template by Targeting Nonconserved Asp856.
Perreault S, Chandrasekhar J, Cui ZH, Evarts J, Hao J, Kaplan JA, Kashishian A, Keegan KS, Kenney T, Koditek D, Lad L, Lepist EI, McGrath ME, Patel L, Phillips B, Therrien J, Treiberg J, Yahiaoui A, Phillips G. Perreault S, et al. Among authors: therrien j. J Med Chem. 2017 Feb 23;60(4):1555-1567. doi: 10.1021/acs.jmedchem.6b01821. Epub 2017 Feb 7. J Med Chem. 2017. PMID: 28106991
2,4,6-Triaminopyrimidine as a Novel Hinge Binder in a Series of PI3Kδ Selective Inhibitors.
Patel L, Chandrasekhar J, Evarts J, Haran AC, Ip C, Kaplan JA, Kim M, Koditek D, Lad L, Lepist EI, McGrath ME, Novikov N, Perreault S, Puri KD, Somoza JR, Steiner BH, Stevens KL, Therrien J, Treiberg J, Villaseñor AG, Yeung A, Phillips G. Patel L, et al. Among authors: therrien j. J Med Chem. 2016 Apr 14;59(7):3532-48. doi: 10.1021/acs.jmedchem.6b00213. Epub 2016 Mar 29. J Med Chem. 2016. PMID: 26980109
Fosfomycin enhances the active transport of tobramycin in Pseudomonas aeruginosa.
MacLeod DL, Velayudhan J, Kenney TF, Therrien JH, Sutherland JL, Barker LM, Baker WR. MacLeod DL, et al. Among authors: therrien jh. Antimicrob Agents Chemother. 2012 Mar;56(3):1529-38. doi: 10.1128/AAC.05958-11. Epub 2012 Jan 9. Antimicrob Agents Chemother. 2012. PMID: 22232284 Free PMC article.
Discovery of Orally Efficacious Phosphoinositide 3-Kinase δ Inhibitors with Improved Metabolic Stability.
Patel L, Chandrasekhar J, Evarts J, Forseth K, Haran AC, Ip C, Kashishian A, Kim M, Koditek D, Koppenol S, Lad L, Lepist EI, McGrath ME, Perreault S, Puri KD, Villaseñor AG, Somoza JR, Steiner BH, Therrien J, Treiberg J, Phillips G. Patel L, et al. Among authors: therrien j. J Med Chem. 2016 Oct 13;59(19):9228-9242. doi: 10.1021/acs.jmedchem.6b01169. Epub 2016 Oct 3. J Med Chem. 2016. PMID: 27660855
Leukaemia hijacks a neural mechanism to invade the central nervous system.
Yao H, Price TT, Cantelli G, Ngo B, Warner MJ, Olivere L, Ridge SM, Jablonski EM, Therrien J, Tannheimer S, McCall CM, Chenn A, Sipkins DA. Yao H, et al. Among authors: therrien j. Nature. 2018 Aug;560(7716):55-60. doi: 10.1038/s41586-018-0342-5. Epub 2018 Jul 18. Nature. 2018. PMID: 30022166
MAGE-A3 is a prognostic biomarker for poor clinical outcome in cutaneous squamous cell carcinoma with perineural invasion via modulation of cell proliferation.
Chen A, Santana AL, Doudican N, Roudiani N, Laursen K, Therrien JP, Lee J, Felsen D, Carucci JA. Chen A, et al. Among authors: therrien jp. PLoS One. 2020 Nov 23;15(11):e0241551. doi: 10.1371/journal.pone.0241551. eCollection 2020. PLoS One. 2020. PMID: 33227008 Free article.
Ecological insights from three decades of animal movement tracking across a changing Arctic.
Davidson SC, Bohrer G, Gurarie E, LaPoint S, Mahoney PJ, Boelman NT, Eitel JUH, Prugh LR, Vierling LA, Jennewein J, Grier E, Couriot O, Kelly AP, Meddens AJH, Oliver RY, Kays R, Wikelski M, Aarvak T, Ackerman JT, Alves JA, Bayne E, Bedrosian B, Belant JL, Berdahl AM, Berlin AM, Berteaux D, Bêty J, Boiko D, Booms TL, Borg BL, Boutin S, Boyd WS, Brides K, Brown S, Bulyuk VN, Burnham KK, Cabot D, Casazza M, Christie K, Craig EH, Davis SE, Davison T, Demma D, DeSorbo CR, Dixon A, Domenech R, Eichhorn G, Elliott K, Evenson JR, Exo KM, Ferguson SH, Fiedler W, Fisk A, Fort J, Franke A, Fuller MR, Garthe S, Gauthier G, Gilchrist G, Glazov P, Gray CE, Grémillet D, Griffin L, Hallworth MT, Harrison AL, Hennin HL, Hipfner JM, Hodson J, Johnson JA, Joly K, Jones K, Katzner TE, Kidd JW, Knight EC, Kochert MN, Kölzsch A, Kruckenberg H, Lagassé BJ, Lai S, Lamarre JF, Lanctot RB, Larter NC, Latham ADM, Latty CJ, Lawler JP, Léandri-Breton DJ, Lee H, Lewis SB, Love OP, Madsen J, Maftei M, Mallory ML, Mangipane B, Markovets MY, Marra PP, McGuire R, McIntyre CL, McKinnon EA, Miller TA, Moonen S, Mu T, Müskens GJDM, Ng J, Nicholson KL, Øien IJ, Overton C, Owen PA, Patterson A, Petersen A, Pokrovsky I, Powell LL, Prieto R, Quillfeldt P, Rausch J, Russell K, Saalfeld ST, Schekkerman H, Schmutz JA, Schwemmer P, Seip DR, Shreading A, Silva MA, Smith BW, Smith F, Smith JP, Snell KRS, Sokolov A, Sokolov V, Solovyeva DV, Sorum MS, Tertitski G, Therrien JF, Thorup K, Tibbitts TL, Tulp I, Uher-Koch BD, van Bemmelen RSA, Van Wilgenburg S, Von Duyke AL, Watson JL, Watts BD, Williams JA, Wilson MT, Wright JR, Yates MA, Yurkowski DJ, Žydelis R, Hebblewhite M. Davidson SC, et al. Among authors: therrien jf. Science. 2020 Nov 6;370(6517):712-715. doi: 10.1126/science.abb7080. Science. 2020. PMID: 33154141
163 results
You have reached the last page of results. A maximum of 10,000 results are available.
Jump to page
Feedback