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Kinesin I-dependent cortical exclusion restricts pole plasm to the oocyte posterior.
Cha BJ, Serbus LR, Koppetsch BS, Theurkauf WE. Cha BJ, et al. Among authors: theurkauf we. Nat Cell Biol. 2002 Aug;4(8):592-8. doi: 10.1038/ncb832. Nat Cell Biol. 2002. PMID: 12134163
We present evidence that microtubule minus ends associate with the entire cortex, and that Kinesin and microtubules are not required for oskar mRNA association with the posterior pole, but prevent ectopic localization of this transcript and the pole plasm proteins Oskar an
We present evidence that microtubule minus ends associate with the entire cortex, and that Kinesin and microtubules are not required
TACCing down the spindle poles.
Theurkauf WE. Theurkauf WE. Nat Cell Biol. 2001 Jul;3(7):E159-61. doi: 10.1038/35083110. Nat Cell Biol. 2001. PMID: 11433309 No abstract available.
DNA-replication/DNA-damage-dependent centrosome inactivation in Drosophila embryos.
Sibon OC, Kelkar A, Lemstra W, Theurkauf WE. Sibon OC, et al. Among authors: theurkauf we. Nat Cell Biol. 2000 Feb;2(2):90-5. doi: 10.1038/35000041. Nat Cell Biol. 2000. PMID: 10655588
Here we show that these segregation failures are associated with the assembly of an anastral microtubule spindle, a mitosis-specific loss of centrosome function, and dissociation of several components of the gamma-tubulin ring complex from a core centrosomal structure. ... …
Here we show that these segregation failures are associated with the assembly of an anastral microtubule spindle, a mitosis-specific …
Centrosomes and the Scrambled protein coordinate microtubule-independent actin reorganization.
Stevenson VA, Kramer J, Kuhn J, Theurkauf WE. Stevenson VA, et al. Among authors: theurkauf we. Nat Cell Biol. 2001 Jan;3(1):68-75. doi: 10.1038/35050579. Nat Cell Biol. 2001. PMID: 11146628
Perinuclear localization and insulin responsiveness of GLUT4 requires cytoskeletal integrity in 3T3-L1 adipocytes.
Guilherme A, Emoto M, Buxton JM, Bose S, Sabini R, Theurkauf WE, Leszyk J, Czech MP. Guilherme A, et al. Among authors: theurkauf we. J Biol Chem. 2000 Dec 8;275(49):38151-9. doi: 10.1074/jbc.M003432200. J Biol Chem. 2000. PMID: 10950952
Using a novel method to purify intracellular GLUT4-enriched membranes, we identified by mass spectrometry the intermediate filament protein vimentin and the microtubule protein alpha-tubulin as components of these membranes. ...
Using a novel method to purify intracellular GLUT4-enriched membranes, we identified by mass spectrometry the intermediate filament p …
Actin cytoskeleton: putting a CAP on actin polymerization.
Stevenson VA, Theurkauf WE. Stevenson VA, et al. Among authors: theurkauf we. Curr Biol. 2000 Oct 5;10(19):R695-7. doi: 10.1016/s0960-9822(00)00712-0. Curr Biol. 2000. PMID: 11050402 Review.
rasiRNAs, DNA damage, and embryonic axis specification.
Theurkauf WE, Klattenhoff C, Bratu DP, McGinnis-Schultz N, Koppetsch BS, Cook HA. Theurkauf WE, et al. Cold Spring Harb Symp Quant Biol. 2006;71:171-80. doi: 10.1101/sqb.2006.71.066. Cold Spring Harb Symp Quant Biol. 2006. PMID: 17381294
We show that mutations in mei-41 and mnk, which encode ATR and Chk2 kinases that function in DNA damage signal transduction, dramatically suppress the cytoskeletal and RNA localization defects associated with rasiRNA mutations. ...We also find that armitage, aubergi
We show that mutations in mei-41 and mnk, which encode ATR and Chk2 kinases that function in DNA damage signal transduction, dramatic
Development. The message is in the translation.
Richter JD, Theurkauf WE. Richter JD, et al. Among authors: theurkauf we. Science. 2001 Jul 6;293(5527):60-2. doi: 10.1126/science.1062237. Science. 2001. PMID: 11441171 No abstract available.
In vivo analysis of Drosophila bicoid mRNA localization reveals a novel microtubule-dependent axis specification pathway.
Cha BJ, Koppetsch BS, Theurkauf WE. Cha BJ, et al. Among authors: theurkauf we. Cell. 2001 Jul 13;106(1):35-46. doi: 10.1016/s0092-8674(01)00419-6. Cell. 2001. PMID: 11461700
We propose that microtubule-dependent Exuperantia-bicoid mRNA complex formation in the nurse cell cytoplasm allows anterior-specific transport on a grossly nonpolar oocyte microtubule network....
We propose that microtubule-dependent Exuperantia-bicoid mRNA complex formation in the nurse cell cytoplasm allows anterior-specific
Anastral meiotic spindle morphogenesis: role of the non-claret disjunctional kinesin-like protein.
Matthies HJ, McDonald HB, Goldstein LS, Theurkauf WE. Matthies HJ, et al. Among authors: theurkauf we. J Cell Biol. 1996 Jul;134(2):455-64. doi: 10.1083/jcb.134.2.455. J Cell Biol. 1996. PMID: 8707829 Free PMC article.
We have used time-lapse laser scanning confocal microscopy to directly examine microtubule reorganization during meiotic spindle assembly in living Drosophila oocytes. ...Based on these observations, we propose that microtubule bundling by the NCD kinesin-like prote
We have used time-lapse laser scanning confocal microscopy to directly examine microtubule reorganization during meiotic spindle asse
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