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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 2
1979 1
1983 1
1985 2
1986 1
1987 3
1988 4
1989 5
1990 6
1991 11
1992 6
1993 7
1994 10
1995 4
1996 7
1997 7
1998 7
1999 13
2000 8
2001 11
2002 4
2003 18
2004 13
2005 15
2006 15
2007 18
2008 27
2009 21
2010 15
2011 14
2012 18
2013 20
2014 21
2015 29
2016 24
2017 23
2018 28
2019 22
2020 27
2021 19
2022 18
2023 19
2024 3

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494 results

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Page 1
Acromegaly.
Chanson P, Salenave S. Chanson P, et al. Orphanet J Rare Dis. 2008 Jun 25;3:17. doi: 10.1186/1750-1172-3-17. Orphanet J Rare Dis. 2008. PMID: 18578866 Free PMC article. Review.
The main clinical features are broadened extremities (hands and feet), widened thickened and stubby fingers, and thickened soft tissue. The facial aspect is characteristic and includes a widened and thickened nose, prominent cheekbones, forehead bulges, thick …
The main clinical features are broadened extremities (hands and feet), widened thickened and stubby fingers, and thickened sof …
Onychomycosis: a review.
Gupta AK, Stec N, Summerbell RC, Shear NH, Piguet V, Tosti A, Piraccini BM. Gupta AK, et al. J Eur Acad Dermatol Venereol. 2020 Sep;34(9):1972-1990. doi: 10.1111/jdv.16394. Epub 2020 Jun 5. J Eur Acad Dermatol Venereol. 2020. PMID: 32239567 Review.
Onychomycosis is a fungal infection of the nail, causing discoloration and thickening of the affected nail plate, and is the most common nail infection worldwide. ...Microscopy and fungal culture are the gold standard techniques for onychomycosis diagnosis, but high false- …
Onychomycosis is a fungal infection of the nail, causing discoloration and thickening of the affected nail plate, and is the most com …
2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative.
van den Hoogen F, Khanna D, Fransen J, Johnson SR, Baron M, Tyndall A, Matucci-Cerinic M, Naden RP, Medsger TA Jr, Carreira PE, Riemekasten G, Clements PJ, Denton CP, Distler O, Allanore Y, Furst DE, Gabrielli A, Mayes MD, van Laar JM, Seibold JR, Czirjak L, Steen VD, Inanc M, Kowal-Bielecka O, Müller-Ladner U, Valentini G, Veale DJ, Vonk MC, Walker UA, Chung L, Collier DH, Ellen Csuka M, Fessler BJ, Guiducci S, Herrick A, Hsu VM, Jimenez S, Kahaleh B, Merkel PA, Sierakowski S, Silver RM, Simms RW, Varga J, Pope JE. van den Hoogen F, et al. Ann Rheum Dis. 2013 Nov;72(11):1747-55. doi: 10.1136/annrheumdis-2013-204424. Ann Rheum Dis. 2013. PMID: 24092682 Free article.
The system was tested by (1) determining specificity and sensitivity in SSc cases and controls with scleroderma-like disorders, and (2) validating against the combined view of a group of experts on a set of cases with or without SSc. RESULTS: It was determined that skin
The system was tested by (1) determining specificity and sensitivity in SSc cases and controls with scleroderma-like disorders, and (2) vali …
Ichthyosis.
Gutiérrez-Cerrajero C, Sprecher E, Paller AS, Akiyama M, Mazereeuw-Hautier J, Hernández-Martín A, González-Sarmiento R. Gutiérrez-Cerrajero C, et al. Nat Rev Dis Primers. 2023 Jan 19;9(1):2. doi: 10.1038/s41572-022-00412-3. Nat Rev Dis Primers. 2023. PMID: 36658199 Review.
The resultant skin barrier dysfunction leads to increased transepidermal water loss and inflammation. Disordered cornification is clinically characterized by skin scaling with various degrees of thickening, desquamation (peeling) and erythema (redness). ...
The resultant skin barrier dysfunction leads to increased transepidermal water loss and inflammation. Disordered cornification is cli …
Scleroderma with an update about clinico-pathological correlation.
Rongioletti F, Ferreli C, Atzori L, Bottoni U, Soda G. Rongioletti F, et al. G Ital Dermatol Venereol. 2018 Apr;153(2):208-215. doi: 10.23736/S0392-0488.18.05922-9. Epub 2018 Jan 24. G Ital Dermatol Venereol. 2018. PMID: 29368844 Free article. Review.
According to 2013 ACR/EULAR Classification Criteria for Systemic Sclerosis, developed by the American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR), skin thickening of the fingers extending proximal to the metacarpophalangeal joint …
According to 2013 ACR/EULAR Classification Criteria for Systemic Sclerosis, developed by the American College of Rheumatology (ACR) and the …
Acquired palmoplantar keratoderma.
Patel S, Zirwas M, English JC 3rd. Patel S, et al. Am J Clin Dermatol. 2007;8(1):1-11. doi: 10.2165/00128071-200708010-00001. Am J Clin Dermatol. 2007. PMID: 17298101 Review.
Palmoplantar keratodermas (PPKs) are a diverse entity of disorders that are characterized by abnormal thickening of the skin on the palms and soles. Traditionally they have been classified as either hereditary or acquired and are distinguished from each other on the …
Palmoplantar keratodermas (PPKs) are a diverse entity of disorders that are characterized by abnormal thickening of the skin o …
Systemic sclerosis sine scleroderma.
Kucharz EJ, Kopeć-Mędrek M. Kucharz EJ, et al. Adv Clin Exp Med. 2017 Aug;26(5):875-880. doi: 10.17219/acem/64334. Adv Clin Exp Med. 2017. PMID: 29068586 Free article. Review.
Systemic sclerosis is a rare generalized disease with scleroderma, i.e. skin thickening as one of the most common symptoms. The disease has 2 main subsets, diffuse and limited forms. ...Type III (delayed) is characterized by clinical internal organ involvement typic …
Systemic sclerosis is a rare generalized disease with scleroderma, i.e. skin thickening as one of the most common symptoms. Th …
Eosinophilic fasciitis: From pathophysiology to treatment.
Ihn H. Ihn H. Allergol Int. 2019 Oct;68(4):437-439. doi: 10.1016/j.alit.2019.03.001. Epub 2019 Mar 22. Allergol Int. 2019. PMID: 30910631 Free article. Review.
The lesions have been observed extending to the proximal limbs, though never on the face or fingers. En bloc biopsies from the skin to the fascia show marked fascial thickening and inflammatory cell infiltration by the lymphocytes and plasma cells. ...
The lesions have been observed extending to the proximal limbs, though never on the face or fingers. En bloc biopsies from the skin t …
Leprosy. An update: definition, pathogenesis, classification, diagnosis, and treatment.
Eichelmann K, González González SE, Salas-Alanis JC, Ocampo-Candiani J. Eichelmann K, et al. Actas Dermosifiliogr. 2013 Sep;104(7):554-63. doi: 10.1016/j.adengl.2012.03.028. Epub 2013 Jul 17. Actas Dermosifiliogr. 2013. PMID: 23870850 Free article. Review.
Leprosy is a chronic granulomatous disease caused by the bacillus Mycobacterium leprae. It primarily affects the skin and peripheral nerves and is still endemic in various regions of the world. ...Diagnosis is clinical and is made when the patient has at least 1 of the fol …
Leprosy is a chronic granulomatous disease caused by the bacillus Mycobacterium leprae. It primarily affects the skin and peripheral …
Discovery of the IL-23/IL-17 Signaling Pathway and the Treatment of Psoriasis.
Hawkes JE, Yan BY, Chan TC, Krueger JG. Hawkes JE, et al. J Immunol. 2018 Sep 15;201(6):1605-1613. doi: 10.4049/jimmunol.1800013. J Immunol. 2018. PMID: 30181299 Free PMC article. Review.
Psoriasis vulgaris is a common, heterogeneous, chronic inflammatory skin disease characterized by thickened, red, scaly plaques and systemic inflammation. ...Under the regulation of IL-23, T cells that produce high levels of IL-17 create a self-amplifying, feed-forw …
Psoriasis vulgaris is a common, heterogeneous, chronic inflammatory skin disease characterized by thickened, red, scaly plaque …
494 results