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Regulation of bi-directional movement of single kinesin-5 Cin8 molecules.
Thiede C, Fridman V, Gerson-Gurwitz A, Gheber L, Schmidt CF. Thiede C, et al. Bioarchitecture. 2012 Feb 1;2(2):70-74. doi: 10.4161/bioa.20395. Bioarchitecture. 2012. PMID: 22754632 Free PMC article.
Deletion of the Tail Domain of the Kinesin-5 Cin8 Affects Its Directionality.
Düselder A, Fridman V, Thiede C, Wiesbaum A, Goldstein A, Klopfenstein DR, Zaitseva O, Janson ME, Gheber L, Schmidt CF. Düselder A, et al. J Biol Chem. 2015 Jul 3;290(27):16841-50. doi: 10.1074/jbc.M114.620799. Epub 2015 May 19. J Biol Chem. 2015. PMID: 25991727 Free PMC article.
Here we have examined the role of the C-terminal tail domain of Cin8 in regulating directionality. We first constructed a stable dimeric Cin8/kinesin-1 chimera (Cin8Kin), consisting of head and neck linker of Cin8 fused to the stalk of kinesin-1. ...
Here we have examined the role of the C-terminal tail domain of Cin8 in regulating directionality. We first constructed a stable dime …
Directionality of individual kinesin-5 Cin8 motors is modulated by loop 8, ionic strength and microtubule geometry.
Gerson-Gurwitz A, Thiede C, Movshovich N, Fridman V, Podolskaya M, Danieli T, Lakämper S, Klopfenstein DR, Schmidt CF, Gheber L. Gerson-Gurwitz A, et al. EMBO J. 2011 Nov 18;30(24):4942-54. doi: 10.1038/emboj.2011.403. EMBO J. 2011. PMID: 22101328 Free PMC article.
The effect of monastrol on the processive motility of a dimeric kinesin-5 head/kinesin-1 stalk chimera.
Lakämper S, Thiede C, Düselder A, Reiter S, Korneev MJ, Kapitein LC, Peterman EJ, Schmidt CF. Lakämper S, et al. J Mol Biol. 2010 May 28;399(1):1-8. doi: 10.1016/j.jmb.2010.03.009. Epub 2010 Mar 19. J Mol Biol. 2010. PMID: 20227420
Neck-linker length dependence of processive Kinesin-5 motility.
Düselder A, Thiede C, Schmidt CF, Lakämper S. Düselder A, et al. J Mol Biol. 2012 Oct 19;423(2):159-68. doi: 10.1016/j.jmb.2012.06.043. Epub 2012 Jul 9. J Mol Biol. 2012. PMID: 22789568
Endoplasmic reticulum sorting and kinesin-1 command the targeting of axonal GABAB receptors.
Valdés V, Valenzuela JI, Salas DA, Jaureguiberry-Bravo M, Otero C, Thiede C, Schmidt CF, Couve A. Valdés V, et al. PLoS One. 2012;7(8):e44168. doi: 10.1371/journal.pone.0044168. Epub 2012 Aug 27. PLoS One. 2012. PMID: 22952914 Free PMC article.
Differential response to cytotoxic therapy explains treatment dynamics of acute myeloid leukaemia patients: insights from a mathematical modelling approach.
Hoffmann H, Thiede C, Glauche I, Bornhaeuser M, Roeder I. Hoffmann H, et al. Among authors: thiede c. J R Soc Interface. 2020 Sep;17(170):20200091. doi: 10.1098/rsif.2020.0091. Epub 2020 Sep 9. J R Soc Interface. 2020. PMID: 32900301
Sorafenib Maintenance After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia With FLT3-Internal Tandem Duplication Mutation (SORMAIN).
Burchert A, Bug G, Fritz LV, Finke J, Stelljes M, Röllig C, Wollmer E, Wäsch R, Bornhäuser M, Berg T, Lang F, Ehninger G, Serve H, Zeiser R, Wagner EM, Kröger N, Wolschke C, Schleuning M, Götze KS, Schmid C, Crysandt M, Eßeling E, Wolf D, Wang Y, Böhm A, Thiede C, Haferlach T, Michel C, Bethge W, Wündisch T, Brandts C, Harnisch S, Wittenberg M, Hoeffkes HG, Rospleszcz S, Burchardt A, Neubauer A, Brugger M, Strauch K, Schade-Brittinger C, Metzelder SK. Burchert A, et al. Among authors: thiede c. J Clin Oncol. 2020 Sep 10;38(26):2993-3002. doi: 10.1200/JCO.19.03345. Epub 2020 Jul 16. J Clin Oncol. 2020. PMID: 32673171
Quantitative proteomics reveals specific metabolic features of Acute Myeloid Leukemia stem cells.
Raffel S, Klimmeck D, Falcone M, Demir A, Pouya A, Zeisberger P, Lutz C, Tinelli M, Bischel O, Bullinger L, Thiede C, Flörcken A, Westermann J, Ehninger G, Ho AD, Müller-Tidow C, Gu Z, Herrmann C, Krijgsveld J, Trumpp A, Hansson J. Raffel S, et al. Among authors: thiede c. Blood. 2020 Jun 18:blood.2019003654. doi: 10.1182/blood.2019003654. Online ahead of print. Blood. 2020. PMID: 32556243
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