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Link between macrophage migration inhibitory factor and cellular redox regulation.
Thiele M, Bernhagen J. Thiele M, et al. Antioxid Redox Signal. 2005 Sep-Oct;7(9-10):1234-48. doi: 10.1089/ars.2005.7.1234. Antioxid Redox Signal. 2005. PMID: 16115028 Review.
Binding of JAB1/CSN5 to MIF is mediated by the MPN domain but is independent of the JAMM motif.
Burger-Kentischer A, Finkelmeier D, Thiele M, Schmucker J, Geiger G, Tovar GE, Bernhagen J. Burger-Kentischer A, et al. Among authors: thiele m. FEBS Lett. 2005 Mar 14;579(7):1693-701. doi: 10.1016/j.febslet.2005.01.080. FEBS Lett. 2005. PMID: 15757663
Rapid and transient activation of the ERK MAPK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on JAB1/CSN5 and Src kinase activity.
Lue H, Kapurniotu A, Fingerle-Rowson G, Roger T, Leng L, Thiele M, Calandra T, Bucala R, Bernhagen J. Lue H, et al. Among authors: thiele m. Cell Signal. 2006 May;18(5):688-703. doi: 10.1016/j.cellsig.2005.06.013. Epub 2005 Aug 24. Cell Signal. 2006. PMID: 16122907
The cytokine macrophage migration inhibitory factor reduces pro-oxidative stress-induced apoptosis.
Nguyen MT, Lue H, Kleemann R, Thiele M, Tolle G, Finkelmeier D, Wagner E, Braun A, Bernhagen J. Nguyen MT, et al. Among authors: thiele m. J Immunol. 2003 Mar 15;170(6):3337-47. doi: 10.4049/jimmunol.170.6.3337. J Immunol. 2003. PMID: 12626594
Stabilization of atherosclerotic plaques by blockade of macrophage migration inhibitory factor after vascular injury in apolipoprotein E-deficient mice.
Schober A, Bernhagen J, Thiele M, Zeiffer U, Knarren S, Roller M, Bucala R, Weber C. Schober A, et al. Among authors: thiele m. Circulation. 2004 Jan 27;109(3):380-5. doi: 10.1161/01.CIR.0000109201.72441.09. Epub 2003 Dec 22. Circulation. 2004. PMID: 14691040
Role of the Cysteine 81 Residue of Macrophage Migration Inhibitory Factor as a Molecular Redox Switch.
Schinagl A, Kerschbaumer RJ, Sabarth N, Douillard P, Scholz P, Voelkel D, Hollerweger JC, Goettig P, Brandstetter H, Scheiflinger F, Thiele M. Schinagl A, et al. Among authors: thiele m. Biochemistry. 2018 Mar 6;57(9):1523-1532. doi: 10.1021/acs.biochem.7b01156. Epub 2018 Feb 15. Biochemistry. 2018. PMID: 29412660
Oxidized macrophage migration inhibitory factor is a potential new tissue marker and drug target in cancer.
Schinagl A, Thiele M, Douillard P, Völkel D, Kenner L, Kazemi Z, Freissmuth M, Scheiflinger F, Kerschbaumer RJ. Schinagl A, et al. Among authors: thiele m. Oncotarget. 2016 Nov 8;7(45):73486-73496. doi: 10.18632/oncotarget.11970. Oncotarget. 2016. PMID: 27636991 Free PMC article.
Selective Targeting of a Disease-Related Conformational Isoform of Macrophage Migration Inhibitory Factor Ameliorates Inflammatory Conditions.
Thiele M, Kerschbaumer RJ, Tam FW, Völkel D, Douillard P, Schinagl A, Kühnel H, Smith J, McDaid JP, Bhangal G, Yu MC, Pusey CD, Cook HT, Kovarik J, Magelky E, Bhan A, Rieger M, Mudde GC, Ehrlich H, Jilma B, Tilg H, Moschen A, Terhorst C, Scheiflinger F. Thiele M, et al. J Immunol. 2015 Sep 1;195(5):2343-52. doi: 10.4049/jimmunol.1500572. Epub 2015 Jul 24. J Immunol. 2015. PMID: 26209628 Free PMC article.
Neutralization of macrophage migration inhibitory factor (MIF) by fully human antibodies correlates with their specificity for the β-sheet structure of MIF.
Kerschbaumer RJ, Rieger M, Völkel D, Le Roy D, Roger T, Garbaraviciene J, Boehncke WH, Müllberg J, Hoet RM, Wood CR, Antoine G, Thiele M, Savidis-Dacho H, Dockal M, Ehrlich H, Calandra T, Scheiflinger F. Kerschbaumer RJ, et al. Among authors: thiele m. J Biol Chem. 2012 Mar 2;287(10):7446-55. doi: 10.1074/jbc.M111.329664. Epub 2012 Jan 11. J Biol Chem. 2012. PMID: 22238348 Free PMC article.
Pharmacokinetics, disease-modifying activity, and safety of an experimental therapeutic targeting an immunological isoform of macrophage migration inhibitory factor, in rat glomerulonephritis.
Höllriegl W, Bauer A, Baumgartner B, Dietrich B, Douillard P, Kerschbaumer RJ, Höbarth G, McKee JS, Schinagl A, Tam FWK, Thiele M, Weber A, Wolfsegger M, Turecek M, Muchitsch EM, Scheiflinger F, Glantschnig H. Höllriegl W, et al. Among authors: thiele m. Eur J Pharmacol. 2018 Feb 5;820:206-216. doi: 10.1016/j.ejphar.2017.12.040. Epub 2017 Dec 20. Eur J Pharmacol. 2018. PMID: 29274331
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