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Obesity and osteoarthritis, more than just wear and tear: pivotal roles for inflamed adipose tissue and dyslipidaemia in obesity-induced osteoarthritis.

Thijssen E, van Caam A, van der Kraan PM. Thijssen E, et al. Rheumatology (Oxford). 2015 Apr;54(4):588-600. doi: 10.1093/rheumatology/keu464. Epub 2014 Dec 11. Rheumatology (Oxford). 2015. PMID: 25504962 Review.

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TGF-β is a potent inducer of Nerve Growth Factor in articular cartilage via the ALK5-Smad2/3 pathway. Potential role in OA related pain?

Blaney Davidson EN, van Caam AP, Vitters EL, Bennink MB, Thijssen E, van den Berg WB, Koenders MI, van Lent PL, van de Loo FA, van der Kraan PM. Blaney Davidson EN, et al. Among authors: thijssen e. Osteoarthritis Cartilage. 2015 Mar;23(3):478-86. doi: 10.1016/j.joca.2014.12.005. Epub 2014 Dec 18. Osteoarthritis Cartilage. 2015. PMID: 25529198 Free article.

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Expression of TGFβ-family signalling components in ageing cartilage: age-related loss of TGFβ and BMP receptors.

van Caam A, Madej W, Thijssen E, Garcia de Vinuesa A, van den Berg W, Goumans MJ, Ten Dijke P, Blaney Davidson E, van der Kraan PM. van Caam A, et al. Among authors: thijssen e. Osteoarthritis Cartilage. 2016 Jul;24(7):1235-45. doi: 10.1016/j.joca.2016.02.008. Epub 2016 Mar 12. Osteoarthritis Cartilage. 2016. PMID: 26975812 Free article.

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Prehospital triage of patients with suspected non-ST-segment elevation acute coronary syndrome: Rationale and design of the TRIAGE-ACS study.

Demandt JPA, Koks A, Haest R, Heijmen E, Thijssen E, Otterspoor LC, van Veghel D, El Farissi M, Eerdekens R, Vervaat F, Pijls NHJ, Veer MVT, Tonino PAL, Dekker LRC, Vlaar PJ. Demandt JPA, et al. Among authors: thijssen e. Contemp Clin Trials. 2022 Jul 18;119:106854. doi: 10.1016/j.cct.2022.106854. Online ahead of print. Contemp Clin Trials. 2022. PMID: 35863696

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Differential diagnostic performance of a panel of plasma biomarkers for different types of dementia.

Thijssen EH, Verberk IMW, Kindermans J, Abramian A, Vanbrabant J, Ball AJ, Pijnenburg Y, Lemstra AW, van der Flier WM, Stoops E, Hirtz C, Teunissen CE. Thijssen EH, et al. Alzheimers Dement (Amst). 2022 May 15;14(1):e12285. doi: 10.1002/dad2.12285. eCollection 2022. Alzheimers Dement (Amst). 2022. PMID: 35603139 Free PMC article.

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A Randomized First-in-Human Study With UB-312, a UBITh® α-Synuclein Peptide Vaccine.

Yu HJ, Thijssen E, van Brummelen E, van der Plas JL, Radanovic I, Moerland M, Hsieh E, Groeneveld GJ, Dodart JC. Yu HJ, et al. Among authors: thijssen e. Mov Disord. 2022 Jul;37(7):1416-1424. doi: 10.1002/mds.29016. Epub 2022 Apr 15. Mov Disord. 2022. PMID: 35426173 Clinical Trial.

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Safety and pharmacokinetics of multiple dosing with inhalable apomorphine (AZ-009), and its efficacy in a randomized crossover study in Parkinson's disease patients.

Thijssen E, den Heijer JM, Puibert D, van Brummelen EMJ, Naranda T, Groeneveld GJ. Thijssen E, et al. Parkinsonism Relat Disord. 2022 Apr;97:84-90. doi: 10.1016/j.parkreldis.2022.02.014. Epub 2022 Mar 8. Parkinsonism Relat Disord. 2022. PMID: 35366574 Clinical Trial.

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A Randomized Trial Assessing the Safety, Pharmacokinetics, and Efficacy During Morning Off of AZ-009.

Thijssen E, den Heijer J, Puibert D, Moss L, Lei M, Hasegawa D, Keum K, Mochel K, Ezzeldin Sharaf M, Alfredson T, Zeng W, van Brummelen E, Naranda T, Groeneveld GJ. Thijssen E, et al. Mov Disord. 2022 Apr;37(4):790-798. doi: 10.1002/mds.28926. Epub 2022 Jan 20. Mov Disord. 2022. PMID: 35048423 Free PMC article. Clinical Trial.

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Touchscreen-based finger tapping: Repeatability and configuration effects on tapping performance.

Makai-Bölöni S, Thijssen E, van Brummelen EMJ, Groeneveld GJ, Doll RJ. Makai-Bölöni S, et al. Among authors: thijssen e. PLoS One. 2021 Dec 7;16(12):e0260783. doi: 10.1371/journal.pone.0260783. eCollection 2021. PLoS One. 2021. PMID: 34874977 Free PMC article.

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Blood-based biomarkers for Alzheimer's disease: towards clinical implementation.

Teunissen CE, Verberk IMW, Thijssen EH, Vermunt L, Hansson O, Zetterberg H, van der Flier WM, Mielke MM, Del Campo M. Teunissen CE, et al. Among authors: thijssen eh. Lancet Neurol. 2022 Jan;21(1):66-77. doi: 10.1016/S1474-4422(21)00361-6. Epub 2021 Nov 24. Lancet Neurol. 2022. PMID: 34838239 Review.

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