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PDCD2, a protein whose expression is repressed by BCL6, induces apoptosis in human cells by activation of the caspase cascade.
Baron BW, Hyjek E, Gladstone B, Thirman MJ, Baron JM. Baron BW, et al. Among authors: thirman mj. Blood Cells Mol Dis. 2010 Aug 15;45(2):169-75. doi: 10.1016/j.bcmd.2010.04.007. Epub 2010 Jun 3. Blood Cells Mol Dis. 2010. PMID: 20605493
Cloning of cDNAs of the MLL gene that detect DNA rearrangements and altered RNA transcripts in human leukemic cells with 11q23 translocations.
McCabe NR, Burnett RC, Gill HJ, Thirman MJ, Mbangkollo D, Kipiniak M, van Melle E, Ziemin-van der Poel S, Rowley JD, Diaz MO. McCabe NR, et al. Among authors: thirman mj. Proc Natl Acad Sci U S A. 1992 Dec 15;89(24):11794-8. doi: 10.1073/pnas.89.24.11794. Proc Natl Acad Sci U S A. 1992. PMID: 1465401 Free PMC article.
DNA rearrangements and altered transcripts of the MLL gene in a human T-ALL cell line Karpas 45 with a t(X;11) (q13;q23) translocation.
McCabe NR, Kipiniak M, Kobayashi H, Thirman M, Gill H, Rowley JD, Diaz MO. McCabe NR, et al. Genes Chromosomes Cancer. 1994 Mar;9(3):221-4. doi: 10.1002/gcc.2870090311. Genes Chromosomes Cancer. 1994. PMID: 7515665
The human MLL gene: nucleotide sequence, homology to the Drosophila trx zinc-finger domain, and alternative splicing.
Mbangkollo D, Burnett R, McCabe N, Thirman M, Gill H, Yu H, Rowley JD, Diaz MO. Mbangkollo D, et al. DNA Cell Biol. 1995 Jun;14(6):475-83. doi: 10.1089/dna.1995.14.475. DNA Cell Biol. 1995. PMID: 7598802
Detection of MLL gene rearrangements in adult acute lymphoblastic leukemia. A Cancer and Leukemia Group B study.
Stock W, Thirman MJ, Dodge RK, Rowley JD, Diaz MO, Wurster-Hill D, Sobol RE, Davey FR, Larson RA, Westbrook CA, et al. Stock W, et al. Among authors: thirman mj. Leukemia. 1994 Nov;8(11):1918-22. Leukemia. 1994. PMID: 7967737 Clinical Trial.
Molecular analysis of the T-cell acute lymphoblastic leukemia-associated t(1;7)(p34;q34) that fuses LCK and TCRB.
Burnett RC, Thirman MJ, Rowley JD, Diaz MO. Burnett RC, et al. Among authors: thirman mj. Blood. 1994 Aug 15;84(4):1232-6. Blood. 1994. PMID: 8049439
Rearrangements of the MLL gene in therapy-related acute myeloid leukemia in patients previously treated with agents targeting DNA-topoisomerase II.
Super HJ, McCabe NR, Thirman MJ, Larson RA, Le Beau MM, Pedersen-Bjergaard J, Philip P, Diaz MO, Rowley JD. Super HJ, et al. Among authors: thirman mj. Blood. 1993 Dec 15;82(12):3705-11. Blood. 1993. PMID: 8260707
Heterogeneity of breakpoints of 11q23 rearrangements in hematologic malignancies identified with fluorescence in situ hybridization.
Kobayashi H, Espinosa R 3rd, Thirman MJ, Gill HJ, Fernald AA, Diaz MO, Le Beau MM, Rowley JD. Kobayashi H, et al. Among authors: thirman mj. Blood. 1993 Jul 15;82(2):547-51. Blood. 1993. PMID: 8329710
Variability of 11q23 rearrangements in hematopoietic cell lines identified with fluorescence in situ hybridization.
Kobayashi H, Espinosa R 3rd, Thirman MJ, Davis EM, Diaz MO, Le Beau MM, Rowley JD. Kobayashi H, et al. Among authors: thirman mj. Blood. 1993 Jun 1;81(11):3027-33. Blood. 1993. PMID: 8499638
Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia: correlation with scaffold attachment regions and topoisomerase II consensus binding sites.
Broeker PL, Super HG, Thirman MJ, Pomykala H, Yonebayashi Y, Tanabe S, Zeleznik-Le N, Rowley JD. Broeker PL, et al. Among authors: thirman mj. Blood. 1996 Mar 1;87(5):1912-22. Blood. 1996. PMID: 8634439
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