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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 2
1998 2
2000 3
2001 6
2002 3
2003 2
2005 2
2006 1
2008 2
2009 1
2011 5
2012 3
2013 2
2014 4
2015 5
2016 3
2017 2
2018 4
2019 4
2020 13
2021 6
2022 6
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80 results
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Page 1
The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K.
Słabicki M, Kozicka Z, Petzold G, Li YD, Manojkumar M, Bunker RD, Donovan KA, Sievers QL, Koeppel J, Suchyta D, Sperling AS, Fink EC, Gasser JA, Wang LR, Corsello SM, Sellar RS, Jan M, Gillingham D, Scholl C, Fröhling S, Golub TR, Fischer ES, Thomä NH, Ebert BL. Słabicki M, et al. Among authors: thoma nh. Nature. 2020 Sep;585(7824):293-297. doi: 10.1038/s41586-020-2374-x. Epub 2020 Jun 3. Nature. 2020. PMID: 32494016 Free PMC article.
Rational discovery of molecular glue degraders via scalable chemical profiling.
Mayor-Ruiz C, Bauer S, Brand M, Kozicka Z, Siklos M, Imrichova H, Kaltheuner IH, Hahn E, Seiler K, Koren A, Petzold G, Fellner M, Bock C, Müller AC, Zuber J, Geyer M, Thomä NH, Kubicek S, Winter GE. Mayor-Ruiz C, et al. Among authors: thoma nh. Nat Chem Biol. 2020 Nov;16(11):1199-1207. doi: 10.1038/s41589-020-0594-x. Epub 2020 Aug 3. Nat Chem Biol. 2020. PMID: 32747809 Free PMC article.
BANP opens chromatin and activates CpG-island-regulated genes.
Grand RS, Burger L, Gräwe C, Michael AK, Isbel L, Hess D, Hoerner L, Iesmantavicius V, Durdu S, Pregnolato M, Krebs AR, Smallwood SA, Thomä N, Vermeulen M, Schübeler D. Grand RS, et al. Among authors: thoma n. Nature. 2021 Aug;596(7870):133-137. doi: 10.1038/s41586-021-03689-8. Epub 2021 Jul 7. Nature. 2021. PMID: 34234345
Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide.
Fischer ES, Böhm K, Lydeard JR, Yang H, Stadler MB, Cavadini S, Nagel J, Serluca F, Acker V, Lingaraju GM, Tichkule RB, Schebesta M, Forrester WC, Schirle M, Hassiepen U, Ottl J, Hild M, Beckwith RE, Harper JW, Jenkins JL, Thomä NH. Fischer ES, et al. Among authors: thoma nh. Nature. 2014 Aug 7;512(7512):49-53. doi: 10.1038/nature13527. Epub 2014 Jul 16. Nature. 2014. PMID: 25043012 Free PMC article.
Mechanisms of OCT4-SOX2 motif readout on nucleosomes.
Michael AK, Grand RS, Isbel L, Cavadini S, Kozicka Z, Kempf G, Bunker RD, Schenk AD, Graff-Meyer A, Pathare GR, Weiss J, Matsumoto S, Burger L, Schübeler D, Thomä NH. Michael AK, et al. Among authors: thoma nh. Science. 2020 Jun 26;368(6498):1460-1465. doi: 10.1126/science.abb0074. Epub 2020 Apr 23. Science. 2020. PMID: 32327602
Reading the chromatinized genome.
Michael AK, Thomä NH. Michael AK, et al. Among authors: thoma nh. Cell. 2021 Jul 8;184(14):3599-3611. doi: 10.1016/j.cell.2021.05.029. Epub 2021 Jun 18. Cell. 2021. PMID: 34146479 Free article. Review.
80 results