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Mild behavioral impairment is associated with β-amyloid but not tau or neurodegeneration in cognitively intact elderly individuals.
Lussier FZ, Pascoal TA, Chamoun M, Therriault J, Tissot C, Savard M, Kang MS, Mathotaarachchi S, Benedet AL, Parsons M, Qureshi MNI, Thomas ÉM, Shin M, Dion LA, Massarweh G, Soucy JP, Tsai IH, Vitali P, Ismail Z, Rosa-Neto P, Gauthier S. Lussier FZ, et al. Among authors: thomas em. Alzheimers Dement. 2020 Jan;16(1):192-199. doi: 10.1002/alz.12007. Alzheimers Dement. 2020. PMID: 31914223 Free PMC article.
Association of Apolipoprotein E ε4 With Medial Temporal Tau Independent of Amyloid-β.
Therriault J, Benedet AL, Pascoal TA, Mathotaarachchi S, Chamoun M, Savard M, Thomas E, Kang MS, Lussier F, Tissot C, Parsons M, Qureshi MNI, Vitali P, Massarweh G, Soucy JP, Rej S, Saha-Chaudhuri P, Gauthier S, Rosa-Neto P. Therriault J, et al. JAMA Neurol. 2020 Apr 1;77(4):470-479. doi: 10.1001/jamaneurol.2019.4421. JAMA Neurol. 2020. PMID: 31860000 Free PMC article.
APOEε4 potentiates the relationship between amyloid-β and tau pathologies.
Therriault J, Benedet AL, Pascoal TA, Mathotaarachchi S, Savard M, Chamoun M, Thomas E, Kang MS, Lussier F, Tissot C, Soucy JP, Massarweh G, Rej S, Saha-Chaudhuri P, Poirier J, Gauthier S, Rosa-Neto P; Alzheimer’s Disease Neuroimaging Initiative. Therriault J, et al. Mol Psychiatry. 2021 Oct;26(10):5977-5988. doi: 10.1038/s41380-020-0688-6. Epub 2020 Mar 11. Mol Psychiatry. 2021. PMID: 32161362 Free PMC article.
Topographic Distribution of Amyloid-β, Tau, and Atrophy in Patients With Behavioral/Dysexecutive Alzheimer Disease.
Therriault J, Pascoal TA, Savard M, Benedet AL, Chamoun M, Tissot C, Lussier F, Kang MS, Thomas E, Terada T, Rej S, Massarweh G, Nasreddine Z, Vitali P, Soucy JP, Saha-Chaudhuri P, Gauthier S, Rosa-Neto P. Therriault J, et al. Neurology. 2021 Jan 5;96(1):e81-e92. doi: 10.1212/WNL.0000000000011081. Epub 2020 Oct 22. Neurology. 2021. PMID: 33093220 Free PMC article.
Association between regional tau pathology and neuropsychiatric symptoms in aging and dementia due to Alzheimer's disease.
Tissot C, Therriault J, Pascoal TA, Chamoun M, Lussier FZ, Savard M, Mathotaarachchi SS, L Benedet A, Thomas EM, Parsons M, Nasreddine Z, Rosa-Neto P, Gauthier S. Tissot C, et al. Among authors: thomas em. Alzheimers Dement (N Y). 2021 Mar 31;7(1):e12154. doi: 10.1002/trc2.12154. eCollection 2021. Alzheimers Dement (N Y). 2021. PMID: 33816761 Free PMC article.
[11C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer's disease.
Pascoal TA, Chamoun M, Lax E, Wey HY, Shin M, Ng KP, Kang MS, Mathotaarachchi S, Benedet AL, Therriault J, Lussier FZ, Schroeder FA, DuBois JM, Hightower BG, Gilbert TM, Zürcher NR, Wang C, Hopewell R, Chakravarty M, Savard M, Thomas E, Mohaddes S, Farzin S, Salaciak A, Tullo S, Cuello AC, Soucy JP, Massarweh G, Hwang H, Kobayashi E, Hyman BT, Dickerson BC, Guiot MC, Szyf M, Gauthier S, Hooker JM, Rosa-Neto P. Pascoal TA, et al. Nat Commun. 2022 Jul 19;13(1):4171. doi: 10.1038/s41467-022-30653-5. Nat Commun. 2022. PMID: 35853847 Free PMC article.
Intrinsic connectivity of the human brain provides scaffold for tau aggregation in clinical variants of Alzheimer's disease.
Therriault J, Pascoal TA, Savard M, Mathotaarachchi S, Benedet AL, Chamoun M, Tissot C, Lussier FZ, Rahmouni N, Stevenson J, Qureshi MNI, Kang MS, Thomas É, Vitali P, Soucy JP, Massarweh G, Saha-Chaudhuri P, Gauthier S, Rosa-Neto P. Therriault J, et al. Sci Transl Med. 2022 Aug 24;14(659):eabc8693. doi: 10.1126/scitranslmed.abc8693. Epub 2022 Aug 24. Sci Transl Med. 2022. PMID: 36001678
Author Correction: [11C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer's disease.
Pascoal TA, Chamoun M, Lax E, Wey HY, Shin M, Ng KP, Kang MS, Mathotaarachchi S, Benedet AL, Therriault J, Lussier FZ, Schroeder FA, DuBois JM, Hightower BG, Gilbert TM, Zürcher NR, Wang C, Hopewell R, Chakravarty M, Savard M, Thomas E, Mohaddes S, Farzin S, Salaciak A, Tullo S, Cuello AC, Soucy JP, Massarweh G, Hwang H, Kobayashi E, Hyman BT, Dickerson BC, Guiot MC, Szyf M, Gauthier S, Hooker JM, Rosa-Neto P. Pascoal TA, et al. Nat Commun. 2022 Oct 3;13(1):5833. doi: 10.1038/s41467-022-33668-0. Nat Commun. 2022. PMID: 36192402 Free PMC article. No abstract available.
Verbal memory formation across PET-based Braak stages of tau accumulation in Alzheimer's disease.
Fernández Arias J, Therriault J, Thomas E, Lussier FZ, Bezgin G, Tissot C, Servaes S, Mathotaarachchi SS, Schoemaker D, Stevenson J, Rahmouni N, Kang MS, Pallen V, Poltronetti NM, Wang YT, Kunach P, Chamoun M, Quispialaya S KM, Vitali P, Massarweh G, Gauthier S, Rajah MN, Pascoal T, Rosa-Neto P. Fernández Arias J, et al. Brain Commun. 2023 May 18;5(3):fcad146. doi: 10.1093/braincomms/fcad146. eCollection 2023. Brain Commun. 2023. PMID: 37252014 Free PMC article.
Hippocampal subfield associations with memory depend on stimulus modality and retrieval mode.
Aumont E, Bussy A, Bedard MA, Bezgin G, Therriault J, Savard M, Fernandez Arias J, Sziklas V, Vitali P, Poltronetti NM, Pallen V, Thomas E, Gauthier S, Kobayashi E, Rahmouni N, Stevenson J, Tissot C, Chakravarty MM, Rosa-Neto P. Aumont E, et al. Brain Commun. 2023 Nov 9;5(6):fcad309. doi: 10.1093/braincomms/fcad309. eCollection 2023. Brain Commun. 2023. PMID: 38035364 Free PMC article.
154 results