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160 results
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Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells.
Thomas KR, Capecchi MR. Thomas KR, et al. Cell. 1987 Nov 6;51(3):503-12. doi: 10.1016/0092-8674(87)90646-5. Cell. 1987. PMID: 2822260
High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors.
Thomas KR, Deng C, Capecchi MR. Thomas KR, et al. Mol Cell Biol. 1992 Jul;12(7):2919-23. doi: 10.1128/mcb.12.7.2919. Mol Cell Biol. 1992. PMID: 1620105 Free PMC article.
Swaying is a mutant allele of the proto-oncogene Wnt-1.
Thomas KR, Musci TS, Neumann PE, Capecchi MR. Thomas KR, et al. Cell. 1991 Nov 29;67(5):969-76. doi: 10.1016/0092-8674(91)90369-a. Cell. 1991. PMID: 1835670
Introduction of a lacZ reporter gene into the mouse int-2 locus by homologous recombination.
Mansour SL, Thomas KR, Deng CX, Capecchi MR. Mansour SL, et al. Among authors: thomas kr. Proc Natl Acad Sci U S A. 1990 Oct;87(19):7688-92. doi: 10.1073/pnas.87.19.7688. Proc Natl Acad Sci U S A. 1990. PMID: 2120706 Free PMC article.
Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development.
Thomas KR, Capecchi MR. Thomas KR, et al. Nature. 1990 Aug 30;346(6287):847-50. doi: 10.1038/346847a0. Nature. 1990. PMID: 2202907
Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes.
Mansour SL, Thomas KR, Capecchi MR. Mansour SL, et al. Among authors: thomas kr. Nature. 1988 Nov 24;336(6197):348-52. doi: 10.1038/336348a0. Nature. 1988. PMID: 3194019
The knockout mouse: six years old and growing stronger.
Thomas KR. Thomas KR. Am J Respir Cell Mol Biol. 1995 May;12(5):461-3. doi: 10.1165/ajrcmb.12.5.7742010. Am J Respir Cell Mol Biol. 1995. PMID: 7742010 Review. No abstract available.
Impact of gene targeting on medicine.
Thomas KR. Thomas KR. Mol Genet Med. 1994;4:153-78. doi: 10.1016/b978-0-12-462004-9.50009-8. Mol Genet Med. 1994. PMID: 7981629 Review. No abstract available.
Location of crossovers during gene targeting with insertion and replacement vectors.
Deng C, Thomas KR, Capecchi MR. Deng C, et al. Among authors: thomas kr. Mol Cell Biol. 1993 Apr;13(4):2134-40. doi: 10.1128/mcb.13.4.2134. Mol Cell Biol. 1993. PMID: 8455602 Free PMC article.
Targeting genes for self-excision in the germ line.
Bunting M, Bernstein KE, Greer JM, Capecchi MR, Thomas KR. Bunting M, et al. Among authors: thomas kr. Genes Dev. 1999 Jun 15;13(12):1524-8. doi: 10.1101/gad.13.12.1524. Genes Dev. 1999. PMID: 10385621 Free PMC article.
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