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8,892 results
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The role of the E6-p53 interaction in the molecular pathogenesis of HPV.
Thomas M, Pim D, Banks L. Thomas M, et al. Oncogene. 1999 Dec 13;18(53):7690-700. doi: 10.1038/sj.onc.1202953. Oncogene. 1999. PMID: 10618709 Review.
Mutation of the p53 gene in human soft tissue sarcomas: association with abnormalities of the RB1 gene.
Stratton MR, Moss S, Warren W, Patterson H, Clark J, Fisher C, Fletcher CD, Ball A, Thomas M, Gusterson BA, et al. Stratton MR, et al. Among authors: thomas m. Oncogene. 1990 Sep;5(9):1297-301. Oncogene. 1990. PMID: 2216456
HPV-18 E6 mediated inhibition of p53 DNA binding activity is independent of E6 induced degradation.
Thomas M, Massimi P, Jenkins J, Banks L. Thomas M, et al. Oncogene. 1995 Jan 19;10(2):261-8. Oncogene. 1995. PMID: 7838526
Mutational analysis of HPV-18 E6 identifies domains required for p53 degradation in vitro, abolition of p53 transactivation in vivo and immortalisation of primary BMK cells.
Pim D, Storey A, Thomas M, Massimi P, Banks L. Pim D, et al. Among authors: thomas m. Oncogene. 1994 Jul;9(7):1869-76. Oncogene. 1994. PMID: 8208532
Induction of apoptosis by p53 is independent of its oligomeric state and can be abolished by HPV-18 E6 through ubiquitin mediated degradation.
Thomas M, Matlashewski G, Pim D, Banks L. Thomas M, et al. Oncogene. 1996 Jul 18;13(2):265-73. Oncogene. 1996. PMID: 8710365
HPV-18 E6 inhibits p53 DNA binding activity regardless of the oligomeric state of p53 or the exact p53 recognition sequence.
Thomas M, Massimi P, Banks L. Thomas M, et al. Oncogene. 1996 Aug 1;13(3):471-80. Oncogene. 1996. PMID: 8760288
Role of a p53 polymorphism in the development of human papillomavirus-associated cancer.
Storey A, Thomas M, Kalita A, Harwood C, Gardiol D, Mantovani F, Breuer J, Leigh IM, Matlashewski G, Banks L. Storey A, et al. Among authors: thomas m. Nature. 1998 May 21;393(6682):229-34. doi: 10.1038/30400. Nature. 1998. PMID: 9607760
Inhibition of Bak-induced apoptosis by HPV-18 E6.
Thomas M, Banks L. Thomas M, et al. Oncogene. 1998 Dec 10;17(23):2943-54. doi: 10.1038/sj.onc.1202223. Oncogene. 1998. PMID: 9881696
Two polymorphic variants of wild-type p53 differ biochemically and biologically.
Thomas M, Kalita A, Labrecque S, Pim D, Banks L, Matlashewski G. Thomas M, et al. Mol Cell Biol. 1999 Feb;19(2):1092-100. doi: 10.1128/mcb.19.2.1092. Mol Cell Biol. 1999. PMID: 9891044 Free PMC article.
Human papillomavirus (HPV) E6 interactions with Bak are conserved amongst E6 proteins from high and low risk HPV types.
Thomas M, Banks L. Thomas M, et al. J Gen Virol. 1999 Jun;80 ( Pt 6):1513-1517. doi: 10.1099/0022-1317-80-6-1513. J Gen Virol. 1999. PMID: 10374970
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