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AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer.
Giffin MJ, Cooke K, Lobenhofer EK, Estrada J, Zhan J, Deegen P, Thomas M, Murawsky CM, Werner J, Liu S, Lee F, Homann O, Friedrich M, Pearson JT, Raum T, Yang Y, Caenepeel S, Stevens J, Beltran PJ, Canon J, Coxon A, Bailis JM, Hughes PE. Giffin MJ, et al. Among authors: thomas m. Clin Cancer Res. 2021 Mar 1;27(5):1526-1537. doi: 10.1158/1078-0432.CCR-20-2845. Epub 2020 Nov 17. Clin Cancer Res. 2021. PMID: 33203642
Immunotherapy combinations overcome resistance to bispecific T cell engager treatment in T cell-cold solid tumors.
Belmontes B, Sawant DV, Zhong W, Tan H, Kaul A, Aeffner F, O'Brien SA, Chun M, Noubade R, Eng J, Ma H, Muenz M, Li P, Alba BM, Thomas M, Cook K, Wang X, DeVoss J, Egen JG, Nolan-Stevaux O. Belmontes B, et al. Among authors: thomas m. Sci Transl Med. 2021 Aug 25;13(608):eabd1524. doi: 10.1126/scitranslmed.abd1524. Sci Transl Med. 2021. PMID: 34433637
FGF21 can be mimicked in vitro and in vivo by a novel anti-FGFR1c/β-Klotho bispecific protein.
Smith R, Duguay A, Bakker A, Li P, Weiszmann J, Thomas MR, Alba BM, Wu X, Gupte J, Yang L, Stevens J, Hamburger A, Smith S, Chen J, Komorowski R, Moore KW, Véniant MM, Li Y. Smith R, et al. Among authors: thomas mr. PLoS One. 2013 Apr 22;8(4):e61432. doi: 10.1371/journal.pone.0061432. Print 2013. PLoS One. 2013. PMID: 23630589 Free PMC article.
Novel protein therapeutic joint retention strategy based on collagen-binding Avimers.
Hulme JT, D'Souza WN, McBride HJ, Yoon BP, Willee AM, Duguay A, Thomas M, Fan B, Dayao MR, Rottman JB, Merriam K, Xie J, Smith R, Alba BM, Case RB, Dang K, Montalvan A, Grinberg N, Sun H, Black RA, Gabel CA, Sims JE, Moore K, Bakker A, Li P. Hulme JT, et al. Among authors: thomas m. J Orthop Res. 2018 Apr;36(4):1238-1247. doi: 10.1002/jor.23756. Epub 2017 Nov 22. J Orthop Res. 2018. PMID: 28971529 Free article.
School racial composition, effect modification by caring teacher/staff presence, and mid/late-life depressive symptoms: findings from the Study of Healthy Aging among African Americans.
Mobley TM, Hayes-Larson E, Wu Y, Peterson RL, George KM, Gilsanz P, Glymour MM, Thomas MD, Barnes LL, Whitmer RA, Mayeda ER. Mobley TM, et al. Among authors: thomas md. Am J Epidemiol. 2024 Apr 17:kwae050. doi: 10.1093/aje/kwae050. Online ahead of print. Am J Epidemiol. 2024. PMID: 38634611
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