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689 results
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Autophagy in metazoans: cell survival in the land of plenty.
Lum JJ, DeBerardinis RJ, Thompson CB. Lum JJ, et al. Nat Rev Mol Cell Biol. 2005 Jun;6(6):439-48. doi: 10.1038/nrm1660. Nat Rev Mol Cell Biol. 2005. PMID: 15928708 Review.
Brick by brick: metabolism and tumor cell growth.
Deberardinis RJ, Sayed N, Ditsworth D, Thompson CB. Deberardinis RJ, et al. Curr Opin Genet Dev. 2008 Feb;18(1):54-61. doi: 10.1016/j.gde.2008.02.003. Epub 2008 Apr 2. Curr Opin Genet Dev. 2008. PMID: 18387799 Free PMC article. Review.
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction.
Wise DR, DeBerardinis RJ, Mancuso A, Sayed N, Zhang XY, Pfeiffer HK, Nissim I, Daikhin E, Yudkoff M, McMahon SB, Thompson CB. Wise DR, et al. Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18782-7. doi: 10.1073/pnas.0810199105. Epub 2008 Nov 24. Proc Natl Acad Sci U S A. 2008. PMID: 19033189 Free PMC article.
DNMT1 is regulated by ATP-citrate lyase and maintains methylation patterns during adipocyte differentiation.
Londoño Gentile T, Lu C, Lodato PM, Tse S, Olejniczak SH, Witze ES, Thompson CB, Wellen KE. Londoño Gentile T, et al. Mol Cell Biol. 2013 Oct;33(19):3864-78. doi: 10.1128/MCB.01495-12. Epub 2013 Jul 29. Mol Cell Biol. 2013. PMID: 23897429 Free PMC article.
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation.
Bungard D, Fuerth BJ, Zeng PY, Faubert B, Maas NL, Viollet B, Carling D, Thompson CB, Jones RG, Berger SL. Bungard D, et al. Science. 2010 Sep 3;329(5996):1201-5. doi: 10.1126/science.1191241. Epub 2010 Jul 15. Science. 2010. PMID: 20647423 Free PMC article.
The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis.
Lum JJ, Bui T, Gruber M, Gordan JD, DeBerardinis RJ, Covello KL, Simon MC, Thompson CB. Lum JJ, et al. Genes Dev. 2007 May 1;21(9):1037-49. doi: 10.1101/gad.1529107. Epub 2007 Apr 16. Genes Dev. 2007. PMID: 17437992 Free PMC article.
Cancer's sweet tooth.
Bui T, Thompson CB. Bui T, et al. Cancer Cell. 2006 Jun;9(6):419-20. doi: 10.1016/j.ccr.2006.05.012. Cancer Cell. 2006. PMID: 16766260
The HIV-1 Vpr and glucocorticoid receptor complex is a gain-of-function interaction that prevents the nuclear localization of PARP-1.
Muthumani K, Choo AY, Zong WX, Madesh M, Hwang DS, Premkumar A, Thieu KP, Emmanuel J, Kumar S, Thompson CB, Weiner DB. Muthumani K, et al. Nat Cell Biol. 2006 Feb;8(2):170-9. doi: 10.1038/ncb1352. Epub 2006 Jan 22. Nat Cell Biol. 2006. PMID: 16429131 Free PMC article.
Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival.
Rathmell JC, Fox CJ, Plas DR, Hammerman PS, Cinalli RM, Thompson CB. Rathmell JC, et al. Mol Cell Biol. 2003 Oct;23(20):7315-28. doi: 10.1128/mcb.23.20.7315-7328.2003. Mol Cell Biol. 2003. PMID: 14517300 Free PMC article.
The molecular determinants of de novo nucleotide biosynthesis in cancer cells.
Tong X, Zhao F, Thompson CB. Tong X, et al. Curr Opin Genet Dev. 2009 Feb;19(1):32-7. doi: 10.1016/j.gde.2009.01.002. Epub 2009 Feb 5. Curr Opin Genet Dev. 2009. PMID: 19201187 Free PMC article. Review.
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