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Dietary flaxseed alters tumor biological markers in postmenopausal breast cancer.
Thompson LU, Chen JM, Li T, Strasser-Weippl K, Goss PE. Thompson LU, et al. Clin Cancer Res. 2005 May 15;11(10):3828-35. doi: 10.1158/1078-0432.CCR-04-2326. Clin Cancer Res. 2005. PMID: 15897583 Clinical Trial.
Flaxseed inhibits metastasis and decreases extracellular vascular endothelial growth factor in human breast cancer xenografts.
Dabrosin C, Chen J, Wang L, Thompson LU. Dabrosin C, et al. Among authors: thompson lu. Cancer Lett. 2002 Nov 8;185(1):31-7. doi: 10.1016/s0304-3835(02)00239-2. Cancer Lett. 2002. PMID: 12142076
Dietary flaxseed inhibits human breast cancer growth and metastasis and downregulates expression of insulin-like growth factor and epidermal growth factor receptor.
Chen J, Stavro PM, Thompson LU. Chen J, et al. Among authors: thompson lu. Nutr Cancer. 2002;43(2):187-92. doi: 10.1207/S15327914NC432_9. Nutr Cancer. 2002. PMID: 12588699
Lignans and tamoxifen, alone or in combination, reduce human breast cancer cell adhesion, invasion and migration in vitro.
Chen J, Thompson LU. Chen J, et al. Among authors: thompson lu. Breast Cancer Res Treat. 2003 Jul;80(2):163-70. doi: 10.1023/A:1024513815374. Breast Cancer Res Treat. 2003. PMID: 12908819
Exposure to flaxseed or its purified lignan during suckling inhibits chemically induced rat mammary tumorigenesis.
Chen J, Tan KP, Ward WE, Thompson LU. Chen J, et al. Among authors: thompson lu. Exp Biol Med (Maywood). 2003 Sep;228(8):951-8. doi: 10.1177/153537020322800811. Exp Biol Med (Maywood). 2003. PMID: 12968067
Ligand-induced regulation of ERalpha and ERbeta is indicative of human breast cancer cell proliferation.
Power KA, Thompson LU. Power KA, et al. Among authors: thompson lu. Breast Cancer Res Treat. 2003 Oct;81(3):209-21. doi: 10.1023/A:1026114501364. Breast Cancer Res Treat. 2003. PMID: 14620916
Mammary gland morphogenesis is enhanced by exposure to flaxseed or its major lignan during suckling in rats.
Tan KP, Chen J, Ward WE, Thompson LU. Tan KP, et al. Among authors: thompson lu. Exp Biol Med (Maywood). 2004 Feb;229(2):147-57. doi: 10.1177/153537020422900203. Exp Biol Med (Maywood). 2004. PMID: 14734793
Supplementation with flaxseed alters estrogen metabolism in postmenopausal women to a greater extent than does supplementation with an equal amount of soy.
Brooks JD, Ward WE, Lewis JE, Hilditch J, Nickell L, Wong E, Thompson LU. Brooks JD, et al. Among authors: thompson lu. Am J Clin Nutr. 2004 Feb;79(2):318-25. doi: 10.1093/ajcn/79.2.318. Am J Clin Nutr. 2004. PMID: 14749240 Clinical Trial.
Dietary flaxseed enhances the inhibitory effect of tamoxifen on the growth of estrogen-dependent human breast cancer (mcf-7) in nude mice.
Chen J, Hui E, Ip T, Thompson LU. Chen J, et al. Among authors: thompson lu. Clin Cancer Res. 2004 Nov 15;10(22):7703-11. doi: 10.1158/1078-0432.CCR-04-1130. Clin Cancer Res. 2004. PMID: 15570004
The inhibitory effect of flaxseed on the growth and metastasis of estrogen receptor negative human breast cancer xenograftsis attributed to both its lignan and oil components.
Wang L, Chen J, Thompson LU. Wang L, et al. Among authors: thompson lu. Int J Cancer. 2005 Sep 20;116(5):793-8. doi: 10.1002/ijc.21067. Int J Cancer. 2005. PMID: 15849746
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