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7,266 results
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The cancer therapeutic potential of Chk1 inhibitors: how mechanistic studies impact on clinical trial design.
Thompson R, Eastman A. Thompson R, et al. Br J Clin Pharmacol. 2013 Sep;76(3):358-69. doi: 10.1111/bcp.12139. Br J Clin Pharmacol. 2013. PMID: 23593991 Free PMC article. Review.
A subset of cancer cell lines is acutely sensitive to the Chk1 inhibitor MK-8776 as monotherapy due to CDK2 activation in S phase.
Sakurikar N, Thompson R, Montano R, Eastman A. Sakurikar N, et al. Among authors: thompson r. Oncotarget. 2016 Jan 12;7(2):1380-94. doi: 10.18632/oncotarget.6364. Oncotarget. 2016. PMID: 26595527 Free PMC article.
Sensitization of human cancer cells to gemcitabine by the Chk1 inhibitor MK-8776: cell cycle perturbation and impact of administration schedule in vitro and in vivo.
Montano R, Thompson R, Chung I, Hou H, Khan N, Eastman A. Montano R, et al. Among authors: thompson r. BMC Cancer. 2013 Dec 21;13:604. doi: 10.1186/1471-2407-13-604. BMC Cancer. 2013. PMID: 24359526 Free PMC article.
The Mre11 nuclease is critical for the sensitivity of cells to Chk1 inhibition.
Thompson R, Montano R, Eastman A. Thompson R, et al. PLoS One. 2012;7(8):e44021. doi: 10.1371/journal.pone.0044021. Epub 2012 Aug 24. PLoS One. 2012. PMID: 22937147 Free PMC article.
Suppression of apoptosis by PIF1 helicase in human tumor cells.
Gagou ME, Ganesh A, Thompson R, Phear G, Sanders C, Meuth M. Gagou ME, et al. Among authors: thompson r. Cancer Res. 2011 Jul 15;71(14):4998-5008. doi: 10.1158/0008-5472.CAN-10-4404. Epub 2011 May 26. Cancer Res. 2011. PMID: 21616935
Treatment with the Chk1 inhibitor Gö6976 enhances cisplatin cytotoxicity in SCLC cells.
Thompson R, Meuth M, Woll P, Zhu Y, Danson S. Thompson R, et al. Int J Oncol. 2012 Jan;40(1):194-202. doi: 10.3892/ijo.2011.1187. Epub 2011 Sep 5. Int J Oncol. 2012. PMID: 21894433
High plasma salivary α-amylase, but not high AMY1 copy number, associated with low obesity rate in Qatari adults: cross-sectional study.
Al-Akl N, Thompson RI, Arredouani A. Al-Akl N, et al. Among authors: thompson ri. Sci Rep. 2020 Oct 21;10(1):17918. doi: 10.1038/s41598-020-74864-6. Sci Rep. 2020. PMID: 33087771
Free-breathing simultaneous myocardial T1 and T2 mapping with whole left ventricle coverage.
Guo R, Cai X, Kucukseymen S, Rodriguez J, Paskavitz A, Pierce P, Goddu B, Thompson RB, Nezafat R. Guo R, et al. Among authors: thompson rb. Magn Reson Med. 2020 Oct 20. doi: 10.1002/mrm.28506. Online ahead of print. Magn Reson Med. 2020. PMID: 33078443
Temporal proteomic profiling reveals insight into critical developmental processes and temperature-influenced physiological response differences in a bivalve mollusc.
Trigg SA, Mitchell KR, Thompson RE, Eudeline B, Vadopalas B, Timmins-Schiffman EB, Roberts SB. Trigg SA, et al. Among authors: thompson re. BMC Genomics. 2020 Oct 19;21(1):723. doi: 10.1186/s12864-020-07127-3. BMC Genomics. 2020. PMID: 33076839 Free PMC article.
Cholestasis Due to USP53 Deficiency.
Bull LN, Ellmers R, Foskett P, Strautnieks S, Sambrotta M, Czubkowski P, Jankowska I, Wagner B, Deheragoda M, Thompson RJ. Bull LN, et al. Among authors: thompson rj. J Pediatr Gastroenterol Nutr. 2020 Oct 16. doi: 10.1097/MPG.0000000000002926. Online ahead of print. J Pediatr Gastroenterol Nutr. 2020. PMID: 33075013
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