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420 results

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Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3.
Farrelly LA, Thompson RE, Zhao S, Lepack AE, Lyu Y, Bhanu NV, Zhang B, Loh YE, Ramakrishnan A, Vadodaria KC, Heard KJ, Erikson G, Nakadai T, Bastle RM, Lukasak BJ, Zebroski H 3rd, Alenina N, Bader M, Berton O, Roeder RG, Molina H, Gage FH, Shen L, Garcia BA, Li H, Muir TW, Maze I. Farrelly LA, et al. Among authors: thompson re. Nature. 2019 Mar;567(7749):535-539. doi: 10.1038/s41586-019-1024-7. Epub 2019 Mar 13. Nature. 2019. PMID: 30867594 Free PMC article.
Protein engineering through tandem transamidation.
Thompson RE, Stevens AJ, Muir TW. Thompson RE, et al. Nat Chem. 2019 Aug;11(8):737-743. doi: 10.1038/s41557-019-0281-2. Epub 2019 Jul 1. Nat Chem. 2019. PMID: 31263208 Free PMC article.
Histone H3Q5 serotonylation stabilizes H3K4 methylation and potentiates its readout.
Zhao S, Chuh KN, Zhang B, Dul BE, Thompson RE, Farrelly LA, Liu X, Xu N, Xue Y, Roeder RG, Maze I, Muir TW, Li H. Zhao S, et al. Among authors: thompson re. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2016742118. doi: 10.1073/pnas.2016742118. Proc Natl Acad Sci U S A. 2021. PMID: 33526675 Free PMC article.
Chemoenzymatic Semisynthesis of Proteins.
Thompson RE, Muir TW. Thompson RE, et al. Chem Rev. 2020 Mar 25;120(6):3051-3126. doi: 10.1021/acs.chemrev.9b00450. Epub 2019 Nov 27. Chem Rev. 2020. PMID: 31774265 Free PMC article. Review.
A Genetically Encoded Approach for Breaking Chromatin Symmetry.
Lukasak BJ, Thompson RE, Mitchener MM, Feng VJ, Bagert JD, Muir TW. Lukasak BJ, et al. Among authors: thompson re. ACS Cent Sci. 2022 Feb 23;8(2):176-183. doi: 10.1021/acscentsci.1c01332. Epub 2022 Feb 1. ACS Cent Sci. 2022. PMID: 35233450 Free PMC article.
Improved protein splicing using embedded split inteins.
Gramespacher JA, Stevens AJ, Thompson RE, Muir TW. Gramespacher JA, et al. Among authors: thompson re. Protein Sci. 2018 Mar;27(3):614-619. doi: 10.1002/pro.3357. Epub 2018 Jan 17. Protein Sci. 2018. PMID: 29226478 Free PMC article.
Trial Readiness of Cavernous Malformations With Symptomatic Hemorrhage, Part II: Biomarkers and Trial Modeling.
Hage S, Kinkade S, Girard R, Flemming KD, Kim H, Torbey MT, Huang J, Huston J 3rd, Shu Y, Selwyn RG, Hart BL, Mabray MC, Feghali J, Sair HI, Narvid J, Lupo JM, Lee J, Stadnik A, Alcazar-Felix RJ, Shenkar R, Hobson N, DeBiasse D, Lane K, McBee NA, Treine K, Ostapkovich N, Wang Y, Thompson RE, Koenig JI, Carroll T, Hanley DF Jr, Awad IA. Hage S, et al. Among authors: thompson re. Stroke. 2024 Jan;55(1):31-39. doi: 10.1161/STROKEAHA.123.044083. Epub 2023 Dec 22. Stroke. 2024. PMID: 38134265
Clinical Trial Protocol for BEACH: A Phase 2a Study of MW189 in Patients with Acute Nontraumatic Intracerebral Hemorrhage.
Avadhani R, Ziai WC, Thompson RE, Mould WA, Lane K, Nanni A, Iacobelli M, Sharrock MF, Sansing LH, Van Eldik LJ, Hanley DF; BEACH trial consortium. Avadhani R, et al. Among authors: thompson re. Neurocrit Care. 2024 Apr;40(2):807-815. doi: 10.1007/s12028-023-01867-2. Epub 2023 Nov 2. Neurocrit Care. 2024. PMID: 37919545 Free PMC article.
420 results