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Nutrient scavenging-fueled growth in pancreatic cancer depends on caveolae-mediated endocytosis under nutrient-deprived conditions.
Wolfe AR, Cui T, Baie S, Corrales-Guerrero S, Webb A, Castro-Aceituno V, Shyu DL, Karasinska JM, Topham JT, Renouf DJ, Schaeffer DF, Halloran M, Packard R, Robb R, Chen W, Denko N, Lisanti M, Thompson TC, Frank P, Williams TM. Wolfe AR, et al. Among authors: thompson tc. Sci Adv. 2024 Mar;10(9):eadj3551. doi: 10.1126/sciadv.adj3551. Epub 2024 Mar 1. Sci Adv. 2024. PMID: 38427741 Free PMC article.
SPOP Mutations Target STING1 Signaling in Prostate Cancer and Create Therapeutic Vulnerabilities to PARP Inhibitor-Induced Growth Suppression.
Geng C, Zhang MC, Manyam GC, Vykoukal JV, Fahrmann JF, Peng S, Wu C, Park S, Kondraganti S, Wang D, Robinson BD, Loda M, Barbieri CE, Yap TA, Corn PG, Hanash S, Broom BM, Pilié PG, Thompson TC. Geng C, et al. Among authors: thompson tc. Clin Cancer Res. 2023 Nov 1;29(21):4464-4478. doi: 10.1158/1078-0432.CCR-23-1439. Clin Cancer Res. 2023. PMID: 37581614
The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62.
Linares JF, Cid-Diaz T, Duran A, Osrodek M, Martinez-Ordoñez A, Reina-Campos M, Kuo HH, Elemento O, Martin ML, Cordes T, Thompson TC, Metallo CM, Moscat J, Diaz-Meco MT. Linares JF, et al. Among authors: thompson tc. Cell Rep. 2022 May 10;39(6):110792. doi: 10.1016/j.celrep.2022.110792. Cell Rep. 2022. PMID: 35545049 Free PMC article.
PARP and CDK4/6 Inhibitor Combination Therapy Induces Apoptosis and Suppresses Neuroendocrine Differentiation in Prostate Cancer.
Wu C, Peng S, Pilié PG, Geng C, Park S, Manyam GC, Lu Y, Yang G, Tang Z, Kondraganti S, Wang D, Hudgens CW, Ledesma DA, Marques-Piubelli ML, Torres-Cabala CA, Curry JL, Troncoso P, Corn PG, Broom BM, Thompson TC. Wu C, et al. Among authors: thompson tc. Mol Cancer Ther. 2021 Sep;20(9):1680-1691. doi: 10.1158/1535-7163.MCT-20-0848. Epub 2021 Jun 22. Mol Cancer Ther. 2021. PMID: 34158347 Free PMC article.
Optimizing the diagnosis and management of ductal prostate cancer.
Ranasinghe W, Shapiro DD, Zhang M, Bathala T, Navone N, Thompson TC, Broom B, Aparicio A, Tu SM, Tang C, Davis JW, Pisters L, Chapin BF. Ranasinghe W, et al. Among authors: thompson tc. Nat Rev Urol. 2021 Jun;18(6):337-358. doi: 10.1038/s41585-021-00447-3. Epub 2021 Apr 6. Nat Rev Urol. 2021. PMID: 33824525 Review.
260 results