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A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells.
Lee JS, Heo J, Libbrecht L, Chu IS, Kaposi-Novak P, Calvisi DF, Mikaelyan A, Roberts LR, Demetris AJ, Sun Z, Nevens F, Roskams T, Thorgeirsson SS. Lee JS, et al. Nat Med. 2006 Apr;12(4):410-6. doi: 10.1038/nm1377. Epub 2006 Mar 12. Nat Med. 2006. PMID: 16532004
Transgenic mouse model for synergistic effects of nuclear oncogenes and growth factors in tumorigenesis: interaction of c-myc and transforming growth factor alpha in hepatic oncogenesis.
Murakami H, Sanderson ND, Nagy P, Marino PA, Merlino G, Thorgeirsson SS. Murakami H, et al. Cancer Res. 1993 Apr 15;53(8):1719-23. Cancer Res. 1993. PMID: 8467484
Regulation and function of the multidrug resistance genes in liver.
Silverman JA, Thorgeirsson SS. Silverman JA, et al. Prog Liver Dis. 1995;13:101-23. Prog Liver Dis. 1995. PMID: 9224499 Review.
Specific fate decisions in adult hepatic progenitor cells driven by MET and EGFR signaling.
Kitade M, Factor VM, Andersen JB, Tomokuni A, Kaji K, Akita H, Holczbauer A, Seo D, Marquardt JU, Conner EA, Lee SB, Lee YH, Thorgeirsson SS. Kitade M, et al. Genes Dev. 2013 Aug 1;27(15):1706-17. doi: 10.1101/gad.214601.113. Genes Dev. 2013. PMID: 23913923 Free PMC article.
Hepatocyte-specific c-Met deletion disrupts redox homeostasis and sensitizes to Fas-mediated apoptosis.
Gómez-Quiroz LE, Factor VM, Kaposi-Novak P, Coulouarn C, Conner EA, Thorgeirsson SS. Gómez-Quiroz LE, et al. J Biol Chem. 2008 May 23;283(21):14581-9. doi: 10.1074/jbc.M707733200. Epub 2008 Mar 18. J Biol Chem. 2008. PMID: 18348981 Free PMC article.
Loss of hepatocyte growth factor/c-Met signaling pathway accelerates early stages of N-nitrosodiethylamine induced hepatocarcinogenesis.
Takami T, Kaposi-Novak P, Uchida K, Gomez-Quiroz LE, Conner EA, Factor VM, Thorgeirsson SS. Takami T, et al. Cancer Res. 2007 Oct 15;67(20):9844-51. doi: 10.1158/0008-5472.CAN-07-1905. Cancer Res. 2007. PMID: 17942915
Triiodothyronine accelerates differentiation of rat liver progenitor cells into hepatocytes.
László V, Dezso K, Baghy K, Papp V, Kovalszky I, Sáfrány G, Thorgeirsson SS, Nagy P, Paku S. László V, et al. Histochem Cell Biol. 2008 Nov;130(5):1005-14. doi: 10.1007/s00418-008-0482-z. Epub 2008 Jul 29. Histochem Cell Biol. 2008. PMID: 18663461
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