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Mechanism of the degradation of non-enzymatically glycated proteins under physiological conditions. Studies with the model fructosamine, N epsilon-(1-deoxy-D-fructos-1-yl)hippuryl-lysine.
Smith PR, Thornalley PJ. Smith PR, et al. Among authors: thornalley pj. Eur J Biochem. 1992 Dec 15;210(3):729-39. doi: 10.1111/j.1432-1033.1992.tb17474.x. Eur J Biochem. 1992. PMID: 1483456
Inhibitory effect of superoxide dismutase on fructosamine assay.
Jones AF, Winkles JW, Thornalley PJ, Lunec J, Jennings PE, Barnett AH. Jones AF, et al. Among authors: thornalley pj. Clin Chem. 1987 Jan;33(1):147-9. Clin Chem. 1987. PMID: 3802464
Evidence against the formation of 2-amino-6-(2-formyl-5-hydroxymethyl-pyrrol-1-yl)-hexanoic acid ('pyrraline') as an early-stage product or advanced glycation end product in non-enzymic protein glycation.
Smith PR, Somani HH, Thornalley PJ, Benn J, Sonksen PH. Smith PR, et al. Among authors: thornalley pj. Clin Sci (Lond). 1993 Jan;84(1):87-93. doi: 10.1042/cs0840087. Clin Sci (Lond). 1993. PMID: 8382140
Accumulation of fructosyl-lysine and advanced glycation end products in the kidney, retina and peripheral nerve of streptozotocin-induced diabetic rats.
Karachalias N, Babaei-Jadidi R, Ahmed N, Thornalley PJ. Karachalias N, et al. Among authors: thornalley pj. Biochem Soc Trans. 2003 Dec;31(Pt 6):1423-5. doi: 10.1042/bst0311423. Biochem Soc Trans. 2003. PMID: 14641079 Review.
Nepsilon-(Carboxymethyl)lysine and 3-DG-imidazolone are major AGE structures in protein modification by 3-deoxyglucosone.
Jono T, Nagai R, Lin X, Ahmed N, Thornalley PJ, Takeya M, Horiuchi S. Jono T, et al. Among authors: thornalley pj. J Biochem. 2004 Sep;136(3):351-8. doi: 10.1093/jb/mvh124. J Biochem. 2004. PMID: 15598892
High-dose thiamine therapy counters dyslipidemia and advanced glycation of plasma protein in streptozotocin-induced diabetic rats.
Karachalias N, Babaei-Jadidi R, Kupich C, Ahmed N, Thornalley PJ. Karachalias N, et al. Among authors: thornalley pj. Ann N Y Acad Sci. 2005 Jun;1043:777-83. doi: 10.1196/annals.1333.090. Ann N Y Acad Sci. 2005. PMID: 16037305
Processing of protein glycation, oxidation and nitrosation adducts in the liver and the effect of cirrhosis.
Ahmed N, Thornalley PJ, Lüthen R, Häussinger D, Sebekova K, Schinzel R, Voelker W, Heidland A. Ahmed N, et al. Among authors: thornalley pj. J Hepatol. 2004 Dec;41(6):913-9. doi: 10.1016/j.jhep.2004.08.007. J Hepatol. 2004. PMID: 15582123
Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry.
Thornalley PJ, Battah S, Ahmed N, Karachalias N, Agalou S, Babaei-Jadidi R, Dawnay A. Thornalley PJ, et al. Biochem J. 2003 Nov 1;375(Pt 3):581-92. doi: 10.1042/BJ20030763. Biochem J. 2003. PMID: 12885296 Free PMC article.
Glycation in diabetic neuropathy: characteristics, consequences, causes, and therapeutic options.
Thornalley PJ. Thornalley PJ. Int Rev Neurobiol. 2002;50:37-57. doi: 10.1016/s0074-7742(02)50072-6. Int Rev Neurobiol. 2002. PMID: 12198817 Review.
Chromatographic assay of glycation adducts in human serum albumin glycated in vitro by derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl-carbamate and intrinsic fluorescence.
Ahmed N, Thornalley PJ. Ahmed N, et al. Among authors: thornalley pj. Biochem J. 2002 May 15;364(Pt 1):15-24. doi: 10.1042/bj3640015. Biochem J. 2002. PMID: 11988071 Free PMC article.
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