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Caspases: killer proteases.
Nicholson DW, Thornberry NA. Nicholson DW, et al. Among authors: thornberry na. Trends Biochem Sci. 1997 Aug;22(8):299-306. doi: 10.1016/s0968-0004(97)01085-2. Trends Biochem Sci. 1997. PMID: 9270303 Review.
Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract.
Wellington CL, Ellerby LM, Hackam AS, Margolis RL, Trifiro MA, Singaraja R, McCutcheon K, Salvesen GS, Propp SS, Bromm M, Rowland KJ, Zhang T, Rasper D, Roy S, Thornberry N, Pinsky L, Kakizuka A, Ross CA, Nicholson DW, Bredesen DE, Hayden MR. Wellington CL, et al. J Biol Chem. 1998 Apr 10;273(15):9158-67. doi: 10.1074/jbc.273.15.9158. J Biol Chem. 1998. PMID: 9535906
Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex.
Rasper DM, Vaillancourt JP, Hadano S, Houtzager VM, Seiden I, Keen SL, Tawa P, Xanthoudakis S, Nasir J, Martindale D, Koop BF, Peterson EP, Thornberry NA, Huang J, MacPherson DP, Black SC, Hornung F, Lenardo MJ, Hayden MR, Roy S, Nicholson DW. Rasper DM, et al. Among authors: thornberry na. Cell Death Differ. 1998 Apr;5(4):271-88. doi: 10.1038/sj.cdd.4400370. Cell Death Differ. 1998. PMID: 10200473
Caspases: key mediators of apoptosis.
Thornberry NA. Thornberry NA. Chem Biol. 1998 May;5(5):R97-103. doi: 10.1016/s1074-5521(98)90615-9. Chem Biol. 1998. PMID: 9578633 Review.
The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis.
Rotonda J, Nicholson DW, Fazil KM, Gallant M, Gareau Y, Labelle M, Peterson EP, Rasper DM, Ruel R, Vaillancourt JP, Thornberry NA, Becker JW. Rotonda J, et al. Among authors: thornberry na. Nat Struct Biol. 1996 Jul;3(7):619-25. doi: 10.1038/nsb0796-619. Nat Struct Biol. 1996. PMID: 8673606
Interleukin-1 beta converting enzyme.
Thornberry NA. Thornberry NA. Methods Enzymol. 1994;244:615-31. doi: 10.1016/0076-6879(94)44045-x. Methods Enzymol. 1994. PMID: 7845238 No abstract available.
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