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Barriers to treatment for visceral leishmaniasis in hyperendemic areas: India, Bangladesh, Nepal, Brazil and Sudan.
Thornton SJ, Wasan KM, Piecuch A, Lynd LL, Wasan EK. Thornton SJ, et al. Drug Dev Ind Pharm. 2010 Nov;36(11):1312-9. doi: 10.3109/03639041003796648. Drug Dev Ind Pharm. 2010. PMID: 20545513 Review.
Treatment with a cholesterol absorption inhibitor (FM-VP4) reduces body mass and adipose accumulation in developing and pre-obese mice.
Thornton SJ, Warburton C, Wasan KM, Kozlowski P. Thornton SJ, et al. Drug Dev Ind Pharm. 2007 Oct;33(10):1058-69. doi: 10.1080/03639040601133746. Drug Dev Ind Pharm. 2007. PMID: 17963113
Visceral leishmaniasis affects liver and spleen concentrations of amphotericin B following administration to mice.
Gershkovich P, Wasan EK, Sivak O, Li R, Zhu X, Werbovetz KA, Tidwell RR, Clement JG, Thornton SJ, Wasan KM. Gershkovich P, et al. Among authors: thornton sj. J Antimicrob Chemother. 2010 Mar;65(3):535-7. doi: 10.1093/jac/dkp465. Epub 2009 Dec 21. J Antimicrob Chemother. 2010. PMID: 20026611
A novel tropically stable oral amphotericin B formulation (iCo-010) exhibits efficacy against visceral Leishmaniasis in a murine model.
Wasan EK, Gershkovich P, Zhao J, Zhu X, Werbovetz K, Tidwell RR, Clement JG, Thornton SJ, Wasan KM. Wasan EK, et al. Among authors: thornton sj. PLoS Negl Trop Dis. 2010 Dec 7;4(12):e913. doi: 10.1371/journal.pntd.0000913. PLoS Negl Trop Dis. 2010. PMID: 21151883 Free PMC article.
The reformulation of amphotericin B for oral administration to treat systemic fungal infections and visceral leishmaniasis.
Thornton SJ, Wasan KM. Thornton SJ, et al. Expert Opin Drug Deliv. 2009 Mar;6(3):271-84. doi: 10.1517/17425240902802861. Expert Opin Drug Deliv. 2009. PMID: 19327044 Review.
Highly effective oral amphotericin B formulation against murine visceral leishmaniasis.
Wasan KM, Wasan EK, Gershkovich P, Zhu X, Tidwell RR, Werbovetz KA, Clement JG, Thornton SJ. Wasan KM, et al. Among authors: thornton sj. J Infect Dis. 2009 Aug 1;200(3):357-60. doi: 10.1086/600105. J Infect Dis. 2009. PMID: 19545212
Enhancing drug absorption using lipids: a case study presenting the development and pharmacological evaluation of a novel lipid-based oral amphotericin B formulation for the treatment of systemic fungal infections.
Sachs-Barrable K, Lee SD, Wasan EK, Thornton SJ, Wasan KM. Sachs-Barrable K, et al. Among authors: thornton sj. Adv Drug Deliv Rev. 2008 Mar 17;60(6):692-701. doi: 10.1016/j.addr.2007.08.042. Epub 2007 Nov 5. Adv Drug Deliv Rev. 2008. PMID: 18053611 Review.
Impact of lipoproteins on the biological activity and disposition of hydrophobic drugs: implications for drug discovery.
Wasan KM, Brocks DR, Lee SD, Sachs-Barrable K, Thornton SJ. Wasan KM, et al. Among authors: thornton sj. Nat Rev Drug Discov. 2008 Jan;7(1):84-99. doi: 10.1038/nrd2353. Nat Rev Drug Discov. 2008. PMID: 18079757 Review.
Dietary supplementation with phytosterol and ascorbic acid reduces body mass accumulation and alters food transit time in a diet-induced obesity mouse model.
Thornton SJ, Wong IT, Neumann R, Kozlowski P, Wasan KM. Thornton SJ, et al. Lipids Health Dis. 2011 Jun 28;10:107. doi: 10.1186/1476-511X-10-107. Lipids Health Dis. 2011. PMID: 21711516 Free PMC article.
The effects of experimentally induced hyperthyroidism on the diving physiology of harbor seals (Phoca vitulina).
Weingartner GM, Thornton SJ, Andrews RD, Enstipp MR, Barts AD, Hochachka PW. Weingartner GM, et al. Among authors: thornton sj. Front Physiol. 2012 Sep 28;3:380. doi: 10.3389/fphys.2012.00380. eCollection 2012. Front Physiol. 2012. PMID: 23060807 Free PMC article.
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