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A comprehensive review of glycosylated bacterial natural products.
Elshahawi SI, Shaaban KA, Kharel MK, Thorson JS. Elshahawi SI, et al. Among authors: Thorson JS. Chem Soc Rev. 2015 Nov 7;44(21):7591-697. doi: 10.1039/c4cs00426d. Chem Soc Rev. 2015. PMID: 25735878 Free PMC article. Review.
Structural and functional characterization of CalS11, a TDP-rhamnose 3'-O-methyltransferase involved in calicheamicin biosynthesis.
Singh S, Chang A, Helmich KE, Bingman CA, Wrobel RL, Beebe ET, Makino S, Aceti DJ, Dyer K, Hura GL, Sunkara M, Morris AJ, Phillips GN Jr, Thorson JS. Singh S, et al. Among authors: Thorson JS. ACS Chem Biol. 2013 Jul 19;8(7):1632-9. doi: 10.1021/cb400068k. Epub 2013 May 23. ACS Chem Biol. 2013. PMID: 23662776 Free PMC article.
Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.
Chang A, Singh S, Helmich KE, Goff RD, Bingman CA, Thorson JS, Phillips GN Jr. Chang A, et al. Among authors: Thorson JS. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17649-54. doi: 10.1073/pnas.1108484108. Epub 2011 Oct 10. Proc Natl Acad Sci U S A. 2011. PMID: 21987796 Free PMC article.
Structural characterization of CalO1: a putative orsellinic acid methyltransferase in the calicheamicin-biosynthetic pathway.
Chang A, Singh S, Bingman CA, Thorson JS, Phillips GN Jr. Chang A, et al. Among authors: Thorson JS. Acta Crystallogr D Biol Crystallogr. 2011 Mar;67(Pt 3):197-203. doi: 10.1107/S090744491100360X. Epub 2011 Feb 15. Acta Crystallogr D Biol Crystallogr. 2011. PMID: 21358050 Free PMC article.
The impact of enzyme engineering upon natural product glycodiversification.
Williams GJ, Gantt RW, Thorson JS. Williams GJ, et al. Among authors: Thorson JS. Curr Opin Chem Biol. 2008 Oct;12(5):556-64. doi: 10.1016/j.cbpa.2008.07.013. Curr Opin Chem Biol. 2008. PMID: 18678278 Free PMC article. Review.
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