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Gut Microbiome Directs Hepatocytes to Recruit MDSCs and Promote Cholangiocarcinoma.
Zhang Q, Ma C, Duan Y, Heinrich B, Rosato U, Diggs LP, Ma L, Roy S, Fu Q, Brown ZJ, Wabitsch S, Thovarai V, Fu J, Feng D, Ruf B, Cui LL, Subramanyam V, Frank KM, Wang S, Kleiner DE, Ritz T, Rupp C, Gao B, Longerich T, Kroemer A, Wang XW, Ruchirawat M, Korangy F, Schnabl B, Trinchieri G, Greten TF. Zhang Q, et al. Among authors: thovarai v. Cancer Discov. 2021 May;11(5):1248-1267. doi: 10.1158/2159-8290.CD-20-0304. Epub 2020 Dec 15. Cancer Discov. 2021. PMID: 33323397 Free PMC article.
Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells.
Ma C, Han M, Heinrich B, Fu Q, Zhang Q, Sandhu M, Agdashian D, Terabe M, Berzofsky JA, Fako V, Ritz T, Longerich T, Theriot CM, McCulloch JA, Roy S, Yuan W, Thovarai V, Sen SK, Ruchirawat M, Korangy F, Wang XW, Trinchieri G, Greten TF. Ma C, et al. Among authors: thovarai v. Science. 2018 May 25;360(6391):eaan5931. doi: 10.1126/science.aan5931. Science. 2018. PMID: 29798856 Free PMC article.
FAM3D is essential for colon homeostasis and host defense against inflammation associated carcinogenesis.
Liang W, Peng X, Li Q, Wang P, Lv P, Song Q, She S, Huang S, Chen K, Gong W, Yuan W, Thovarai V, Yoshimura T, O'huigin C, Trinchieri G, Huang J, Lin S, Yao X, Bian X, Kong W, Xi J, Wang JM, Wang Y. Liang W, et al. Among authors: thovarai v. Nat Commun. 2020 Nov 20;11(1):5912. doi: 10.1038/s41467-020-19691-z. Nat Commun. 2020. PMID: 33219235 Free PMC article.
An Interleukin-23-Interleukin-22 Axis Regulates Intestinal Microbial Homeostasis to Protect from Diet-Induced Atherosclerosis.
Fatkhullina AR, Peshkova IO, Dzutsev A, Aghayev T, McCulloch JA, Thovarai V, Badger JH, Vats R, Sundd P, Tang HY, Kossenkov AV, Hazen SL, Trinchieri G, Grivennikov SI, Koltsova EK. Fatkhullina AR, et al. Among authors: thovarai v. Immunity. 2018 Nov 20;49(5):943-957.e9. doi: 10.1016/j.immuni.2018.09.011. Epub 2018 Oct 30. Immunity. 2018. PMID: 30389414 Free PMC article.
The Antimicrobial Peptide CRAMP Is Essential for Colon Homeostasis by Maintaining Microbiota Balance.
Yoshimura T, McLean MH, Dzutsev AK, Yao X, Chen K, Huang J, Gong W, Zhou J, Xiang Y, H Badger J, O'hUigin C, Thovarai V, Tessarollo L, Durum SK, Trinchieri G, Bian XW, Wang JM. Yoshimura T, et al. Among authors: thovarai v. J Immunol. 2018 Mar 15;200(6):2174-2185. doi: 10.4049/jimmunol.1602073. Epub 2018 Feb 12. J Immunol. 2018. PMID: 29440355 Free PMC article.
20 results