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Phosphatidylinositol 3-kinase signaling determines kidney size.
Chen JK, Nagai K, Chen J, Plieth D, Hino M, Xu J, Sha F, Ikizler TA, Quarles CC, Threadgill DW, Neilson EG, Harris RC. Chen JK, et al. Among authors: threadgill dw. J Clin Invest. 2015 Jun;125(6):2429-44. doi: 10.1172/JCI78945. Epub 2015 May 18. J Clin Invest. 2015. PMID: 25985273 Free PMC article.
EGFR signaling promotes TGFβ-dependent renal fibrosis.
Chen J, Chen JK, Nagai K, Plieth D, Tan M, Lee TC, Threadgill DW, Neilson EG, Harris RC. Chen J, et al. Among authors: threadgill dw. J Am Soc Nephrol. 2012 Feb;23(2):215-24. doi: 10.1681/ASN.2011070645. Epub 2011 Nov 17. J Am Soc Nephrol. 2012. PMID: 22095949 Free PMC article.
Tumor fibroblast-derived epiregulin promotes growth of colitis-associated neoplasms through ERK.
Neufert C, Becker C, Türeci Ö, Waldner MJ, Backert I, Floh K, Atreya I, Leppkes M, Jefremow A, Vieth M, Schneider-Stock R, Klinger P, Greten FR, Threadgill DW, Sahin U, Neurath MF. Neufert C, et al. Among authors: threadgill dw. J Clin Invest. 2013 Apr;123(4):1428-43. doi: 10.1172/JCI63748. Epub 2013 Mar 15. J Clin Invest. 2013. PMID: 23549083 Free PMC article.
Hepatocyte ERBB3 and EGFR are required for maximal CCl4-induced liver fibrosis.
Scheving LA, Zhang X, Threadgill DW, Russell WE. Scheving LA, et al. Among authors: threadgill dw. Am J Physiol Gastrointest Liver Physiol. 2016 Nov 1;311(5):G807-G816. doi: 10.1152/ajpgi.00423.2015. Epub 2016 Sep 1. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 27586651 Free PMC article.
The EGFR is required for proper innervation to the skin.
Maklad A, Nicolai JR, Bichsel KJ, Evenson JE, Lee TC, Threadgill DW, Hansen LA. Maklad A, et al. Among authors: threadgill dw. J Invest Dermatol. 2009 Mar;129(3):690-8. doi: 10.1038/jid.2008.281. Epub 2008 Oct 2. J Invest Dermatol. 2009. PMID: 18830272 Free PMC article.
232 results