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Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension.
Tu L, Desroches-Castan A, Mallet C, Guyon L, Cumont A, Phan C, Robert F, Thuillet R, Bordenave J, Sekine A, Huertas A, Ritvos O, Savale L, Feige JJ, Humbert M, Bailly S, Guignabert C. Tu L, et al. Among authors: thuillet r. Circ Res. 2019 Mar 15;124(6):846-855. doi: 10.1161/CIRCRESAHA.118.313356. Circ Res. 2019. PMID: 30636542 Free article.
Increased pericyte coverage mediated by endothelial-derived fibroblast growth factor-2 and interleukin-6 is a source of smooth muscle-like cells in pulmonary hypertension.
Ricard N, Tu L, Le Hiress M, Huertas A, Phan C, Thuillet R, Sattler C, Fadel E, Seferian A, Montani D, Dorfmüller P, Humbert M, Guignabert C. Ricard N, et al. Among authors: thuillet r. Circulation. 2014 Apr 15;129(15):1586-97. doi: 10.1161/CIRCULATIONAHA.113.007469. Epub 2014 Jan 30. Circulation. 2014. PMID: 24481949
Proinflammatory Signature of the Dysfunctional Endothelium in Pulmonary Hypertension. Role of the Macrophage Migration Inhibitory Factor/CD74 Complex.
Le Hiress M, Tu L, Ricard N, Phan C, Thuillet R, Fadel E, Dorfmüller P, Montani D, de Man F, Humbert M, Huertas A, Guignabert C. Le Hiress M, et al. Among authors: thuillet r. Am J Respir Crit Care Med. 2015 Oct 15;192(8):983-97. doi: 10.1164/rccm.201402-0322OC. Am J Respir Crit Care Med. 2015. PMID: 26203495 Free article.
Dasatinib induces lung vascular toxicity and predisposes to pulmonary hypertension.
Guignabert C, Phan C, Seferian A, Huertas A, Tu L, Thuillet R, Sattler C, Le Hiress M, Tamura Y, Jutant EM, Chaumais MC, Bouchet S, Manéglier B, Molimard M, Rousselot P, Sitbon O, Simonneau G, Montani D, Humbert M. Guignabert C, et al. Among authors: thuillet r. J Clin Invest. 2016 Sep 1;126(9):3207-18. doi: 10.1172/JCI86249. Epub 2016 Aug 2. J Clin Invest. 2016. PMID: 27482885 Free PMC article. Clinical Trial.
Renal Denervation Reduces Pulmonary Vascular Remodeling and Right Ventricular Diastolic Stiffness in Experimental Pulmonary Hypertension.
da Silva Gonçalves Bos D, Happé C, Schalij I, Pijacka W, Paton JFR, Guignabert C, Tu L, Thuillet R, Bogaard HJ, van Rossum AC, Vonk-Noordegraaf A, de Man FS, Handoko ML. da Silva Gonçalves Bos D, et al. Among authors: thuillet r. JACC Basic Transl Sci. 2017 Feb 1;2(1):22-35. doi: 10.1016/j.jacbts.2016.09.007. eCollection 2017 Feb. JACC Basic Transl Sci. 2017. PMID: 29034356 Free PMC article.
A genome-wide association analysis identifies PDE1A|DNAJC10 locus on chromosome 2 associated with idiopathic pulmonary arterial hypertension in a Japanese population.
Kimura M, Tamura Y, Guignabert C, Takei M, Kosaki K, Tanabe N, Tatsumi K, Saji T, Satoh T, Kataoka M, Kamitsuji S, Kamatani N, Thuillet R, Tu L, Humbert M, Fukuda K, Sano M. Kimura M, et al. Among authors: thuillet r. Oncotarget. 2017 Aug 24;8(43):74917-74926. doi: 10.18632/oncotarget.20459. eCollection 2017 Sep 26. Oncotarget. 2017. PMID: 29088834 Free PMC article.
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