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Can oral midazolam predict oral cyclosporine disposition?
Paine MF, Davis CL, Shen DD, Marsh CL, Raisys VA, Thummel KE. Paine MF, et al. Among authors: Thummel KE. Eur J Pharm Sci. 2000 Nov;12(1):51-62. doi: 10.1016/s0928-0987(00)00139-1. Eur J Pharm Sci. 2000. PMID: 11121733
Reduced duodenal cytochrome P450 3A protein expression and catalytic activity in patients with cirrhosis.
McConn DJ 2nd, Lin YS, Mathisen TL, Blough DK, Xu Y, Hashizume T, Taylor SL, Thummel KE, Shuhart MC. McConn DJ 2nd, et al. Among authors: Thummel KE. Clin Pharmacol Ther. 2009 Apr;85(4):387-93. doi: 10.1038/clpt.2008.292. Epub 2009 Feb 11. Clin Pharmacol Ther. 2009. PMID: 19212316 Free PMC article.
Contribution of itraconazole metabolites to inhibition of CYP3A4 in vivo.
Templeton IE, Thummel KE, Kharasch ED, Kunze KL, Hoffer C, Nelson WL, Isoherranen N. Templeton IE, et al. Among authors: Thummel KE. Clin Pharmacol Ther. 2008 Jan;83(1):77-85. doi: 10.1038/sj.clpt.6100230. Epub 2007 May 9. Clin Pharmacol Ther. 2008. PMID: 17495874 Free PMC article. Clinical Trial.
Single-dose disulfiram does not inhibit CYP2A6 activity.
Kharasch ED, Hankins DC, Baxter PJ, Thummel KE. Kharasch ED, et al. Among authors: Thummel KE. Clin Pharmacol Ther. 1998 Jul;64(1):39-45. doi: 10.1016/S0009-9236(98)90020-0. Clin Pharmacol Ther. 1998. PMID: 9695717 Clinical Trial.
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