Thummel KE - Search Results

1

First-pass metabolism of midazolam by the human intestine.

Paine MF, Shen DD, Kunze KL, Perkins JD, Marsh CL, McVicar JP, Barr DM, Gillies BS, Thummel KE. Paine MF, et al. Among authors: thummel ke. Clin Pharmacol Ther. 1996 Jul;60(1):14-24. doi: 10.1016/S0009-9236(96)90162-9. Clin Pharmacol Ther. 1996. PMID: 8689807

2

Metabolism of dapsone to its hydroxylamine by CYP2E1 in vitro and in vivo.

Mitra AK, Thummel KE, Kalhorn TF, Kharasch ED, Unadkat JD, Slattery JT. Mitra AK, et al. Among authors: thummel ke. Clin Pharmacol Ther. 1995 Nov;58(5):556-66. doi: 10.1016/0009-9236(95)90176-0. Clin Pharmacol Ther. 1995. PMID: 7586950 Clinical Trial.

3

Catalytic role of cytochrome P4503A4 in multiple pathways of alfentanil metabolism.

Labroo RB, Thummel KE, Kunze KL, Podoll T, Trager WF, Kharasch ED. Labroo RB, et al. Among authors: thummel ke. Drug Metab Dispos. 1995 Apr;23(4):490-6. Drug Metab Dispos. 1995. PMID: 7600917

4

The erythromycin breath test predicts the clearance of midazolam.

Lown KS, Thummel KE, Benedict PE, Shen DD, Turgeon DK, Berent S, Watkins PB. Lown KS, et al. Among authors: thummel ke. Clin Pharmacol Ther. 1995 Jan;57(1):16-24. doi: 10.1016/0009-9236(95)90261-9. Clin Pharmacol Ther. 1995. PMID: 7828377 Free article.

5

Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test.

Lown KS, Kolars JC, Thummel KE, Barnett JL, Kunze KL, Wrighton SA, Watkins PB. Lown KS, et al. Among authors: thummel ke. Drug Metab Dispos. 1994 Nov-Dec;22(6):947-55. Drug Metab Dispos. 1994. PMID: 7895614

6

Use of midazolam as a human cytochrome P450 3A probe: I. In vitro-in vivo correlations in liver transplant patients.

Thummel KE, Shen DD, Podoll TD, Kunze KL, Trager WF, Hartwell PS, Raisys VA, Marsh CL, McVicar JP, Barr DM, et al. Thummel KE, et al. J Pharmacol Exp Ther. 1994 Oct;271(1):549-56. J Pharmacol Exp Ther. 1994. PMID: 7965755

7

Use of midazolam as a human cytochrome P450 3A probe: II. Characterization of inter- and intraindividual hepatic CYP3A variability after liver transplantation.

Thummel KE, Shen DD, Podoll TD, Kunze KL, Trager WF, Bacchi CE, Marsh CL, McVicar JP, Barr DM, Perkins JD, et al. Thummel KE, et al. J Pharmacol Exp Ther. 1994 Oct;271(1):557-66. J Pharmacol Exp Ther. 1994. PMID: 7965756

8

Human liver microsomal enflurane defluorination catalyzed by cytochrome P-450 2E1.

Thummel KE, Kharasch ED, Podoll T, Kunze K. Thummel KE, et al. Drug Metab Dispos. 1993 Mar-Apr;21(2):350-7. Drug Metab Dispos. 1993. PMID: 8097708

9

Clinical enflurane metabolism by cytochrome P450 2E1.

Kharasch ED, Thummel KE, Mautz D, Bosse S. Kharasch ED, et al. Among authors: thummel ke. Clin Pharmacol Ther. 1994 Apr;55(4):434-40. doi: 10.1038/clpt.1994.53. Clin Pharmacol Ther. 1994. PMID: 8162670 Clinical Trial.

10

Oxidation of acetaminophen to N-acetyl-p-aminobenzoquinone imine by human CYP3A4.

Thummel KE, Lee CA, Kunze KL, Nelson SD, Slattery JT. Thummel KE, et al. Biochem Pharmacol. 1993 Apr 22;45(8):1563-9. doi: 10.1016/0006-2952(93)90295-8. Biochem Pharmacol. 1993. PMID: 8387297

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