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Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer.
Halbrook CJ, Pontious C, Kovalenko I, Lapienyte L, Dreyer S, Lee HJ, Thurston G, Zhang Y, Lazarus J, Sajjakulnukit P, Hong HS, Kremer DM, Nelson BS, Kemp S, Zhang L, Chang D, Biankin A, Shi J, Frankel TL, Crawford HC, Morton JP, Pasca di Magliano M, Lyssiotis CA. Halbrook CJ, et al. Among authors: thurston g. Cell Metab. 2019 Jun 4;29(6):1390-1399.e6. doi: 10.1016/j.cmet.2019.02.001. Epub 2019 Feb 28. Cell Metab. 2019. PMID: 30827862 Free PMC article.
GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis.
Kremer DM, Nelson BS, Lin L, Yarosz EL, Halbrook CJ, Kerk SA, Sajjakulnukit P, Myers A, Thurston G, Hou SW, Carpenter ES, Andren AC, Nwosu ZC, Cusmano N, Wisner S, Mbah NE, Shan M, Das NK, Magnuson B, Little AC, Savani MR, Ramos J, Gao T, Sastra SA, Palermo CF, Badgley MA, Zhang L, Asara JM, McBrayer SK, di Magliano MP, Crawford HC, Shah YM, Olive KP, Lyssiotis CA. Kremer DM, et al. Among authors: thurston g. Nat Commun. 2021 Aug 11;12(1):4860. doi: 10.1038/s41467-021-24859-2. Nat Commun. 2021. PMID: 34381026 Free PMC article.
Hyaluronic acid fuels pancreatic cancer cell growth.
Kim PK, Halbrook CJ, Kerk SA, Radyk M, Wisner S, Kremer DM, Sajjakulnukit P, Andren A, Hou SW, Trivedi A, Thurston G, Anand A, Yan L, Salamanca-Cardona L, Welling SD, Zhang L, Pratt MR, Keshari KR, Ying H, Lyssiotis CA. Kim PK, et al. Among authors: thurston g. Elife. 2021 Dec 24;10:e62645. doi: 10.7554/eLife.62645. Elife. 2021. PMID: 34951587 Free PMC article.
Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context.
Kerk SA, Lin L, Myers AL, Sutton DJ, Andren A, Sajjakulnukit P, Zhang L, Zhang Y, Jiménez JA, Nelson BS, Chen B, Robinson A, Thurston G, Kemp SB, Steele NG, Hoffman MT, Wen HJ, Long D, Ackenhusen SE, Ramos J, Gao X, Nwosu ZC, Galban S, Halbrook CJ, Lombard DB, Piwnica-Worms DR, Ying H, Pasca di Magliano M, Crawford HC, Shah YM, Lyssiotis CA. Kerk SA, et al. Among authors: thurston g. Elife. 2022 Jul 11;11:e73245. doi: 10.7554/eLife.73245. Elife. 2022. PMID: 35815941 Free PMC article.
Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells.
Halbrook CJ, Thurston G, Boyer S, Anaraki C, Jiménez JA, McCarthy A, Steele NG, Kerk SA, Hong HS, Lin L, Law FV, Felton C, Scipioni L, Sajjakulnukit P, Andren A, Beutel AK, Singh R, Nelson BS, Van Den Bergh F, Krall AS, Mullen PJ, Zhang L, Batra S, Morton JP, Stanger BZ, Christofk HR, Digman MA, Beard DA, Viale A, Zhang J, Crawford HC, Pasca di Magliano M, Jorgensen C, Lyssiotis CA. Halbrook CJ, et al. Among authors: thurston g. Nat Cancer. 2022 Nov;3(11):1386-1403. doi: 10.1038/s43018-022-00463-1. Epub 2022 Nov 21. Nat Cancer. 2022. PMID: 36411320 Free PMC article.
Molecular assessment of intratumoral immune cell subsets and potential mechanisms of resistance to odronextamab, a CD20×CD3 bispecific antibody, in patients with relapsed/refractory B-cell non-Hodgkin lymphoma.
Brouwer-Visser J, Fiaschi N, Deering RP, Cygan KJ, Scott D, Jeong S, Boucher L, Gupta NT, Gupta S, Adler C, Topp MS, Bannerji R, Duell J, Advani RH, Flink DM, Chaudhry A, Thurston G, Ambati SR, Jankovic V. Brouwer-Visser J, et al. Among authors: thurston g. J Immunother Cancer. 2024 Mar 21;12(3):e008338. doi: 10.1136/jitc-2023-008338. J Immunother Cancer. 2024. PMID: 38519055 Free PMC article.
Indoor Air Sources of Outdoor Air Pollution: Health Consequences, Policy, and Recommendations: An Official American Thoracic Society Workshop Report.
Nassikas NJ, McCormack MC, Ewart G, Balmes JR, Bond TC, Brigham E, Cromar K, Goldstein AH, Hicks A, Hopke PK, Meyer B, Nazaroff WW, Paulin LM, Rice MB, Thurston GD, Turpin BJ, Vance ME, Weschler CJ, Zhang J, Kipen HM. Nassikas NJ, et al. Among authors: thurston gd. Ann Am Thorac Soc. 2024 Mar;21(3):365-376. doi: 10.1513/AnnalsATS.202312-1067ST. Ann Am Thorac Soc. 2024. PMID: 38426826 Free PMC article.
Climate action has valuable health benefits.
Roca-Barceló A, Rice MB, Nunez Y, Thurston G, Weinmayr G, Straif K, Roscoe C, Ebi KL, Andersen ZJ, de Nazelle A, Negev M. Roca-Barceló A, et al. Among authors: thurston g. Environ Epidemiol. 2024 Jan 12;8(1):e288. doi: 10.1097/EE9.0000000000000288. eCollection 2024 Feb. Environ Epidemiol. 2024. PMID: 38343737 Free PMC article. No abstract available.
Long-term exposure to several constituents and sources of PM2.5 is associated with incidence of upper aerodigestive tract cancers but not gastric cancer: Results from the large pooled European cohort of the ELAPSE project.
Weinmayr G, Chen J, Jaensch A, Skodda L, Rodopoulou S, Strak M, de Hoogh K, Andersen ZJ, Bellander T, Brandt J, Fecht D, Forastiere F, Gulliver J, Hertel O, Hoffmann B, Hvidtfeldt UA, Katsouyanni K, Ketzel M, Leander K, Magnusson PKE, Pershagen G, Rizzuto D, Samoli E, Severi G, Stafoggia M, Tjønneland A, Vermeulen R, Wolf K, Zitt E, Brunekreef B, Thurston G, Hoek G, Raaschou-Nielsen O, Nagel G. Weinmayr G, et al. Among authors: thurston g. Sci Total Environ. 2024 Feb 20;912:168789. doi: 10.1016/j.scitotenv.2023.168789. Epub 2023 Nov 22. Sci Total Environ. 2024. PMID: 37996018
PM2.5 and cardiovascular diseases: State-of-the-Art review.
Krittanawong C, Qadeer YK, Hayes RB, Wang Z, Thurston GD, Virani S, Lavie CJ. Krittanawong C, et al. Among authors: thurston gd. Int J Cardiol Cardiovasc Risk Prev. 2023 Oct 12;19:200217. doi: 10.1016/j.ijcrp.2023.200217. eCollection 2023 Dec. Int J Cardiol Cardiovasc Risk Prev. 2023. PMID: 37869561 Free PMC article. Review.
416 results