Changes in blood pressure, heart rate, and sympathetic activity on abrupt withdrawal of tiamenidine (HOE 440) in essential hypertension.
Campbell BC, Elliott HL, Hamilton CA, Reid JL.
Campbell BC, et al.
Eur J Clin Pharmacol. 1980 Nov;18(6):449-54. doi: 10.1007/BF00874654.
Eur J Clin Pharmacol. 1980.
PMID: 7461012
Clinical Trial.
Ten patients, four male, six female, aged 28--64 years, with essential hypertension, were treated for one year with an imidazoline derivative, tiamenidine. Blood pressure fell from an average of 178/108 mm Hg pretreatment to 152/86 mm Hg after 1 year. Tiamenidine wa …
Ten patients, four male, six female, aged 28--64 years, with essential hypertension, were treated for one year with an imidazoline derivativ …