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Spongian diterpenoids inhibit androgen receptor activity.
Yang YC, Meimetis LG, Tien AH, Mawji NR, Carr G, Wang J, Andersen RJ, Sadar MD. Yang YC, et al. Among authors: tien ah. Mol Cancer Ther. 2013 May;12(5):621-31. doi: 10.1158/1535-7163.MCT-12-0978. Epub 2013 Feb 26. Mol Cancer Ther. 2013. PMID: 23443807 Free PMC article.
Niphatenones, glycerol ethers from the sponge Niphates digitalis block androgen receptor transcriptional activity in prostate cancer cells: structure elucidation, synthesis, and biological activity.
Meimetis LG, Williams DE, Mawji NR, Banuelos CA, Lal AA, Park JJ, Tien AH, Fernandez JG, de Voogd NJ, Sadar MD, Andersen RJ. Meimetis LG, et al. Among authors: tien ah. J Med Chem. 2012 Jan 12;55(1):503-14. doi: 10.1021/jm2014056. Epub 2011 Dec 28. J Med Chem. 2012. PMID: 22148427
An androgen receptor N-terminal domain antagonist for treating prostate cancer.
Myung JK, Banuelos CA, Fernandez JG, Mawji NR, Wang J, Tien AH, Yang YC, Tavakoli I, Haile S, Watt K, McEwan IJ, Plymate S, Andersen RJ, Sadar MD. Myung JK, et al. Among authors: tien ah. J Clin Invest. 2013 Jul;123(7):2948-60. doi: 10.1172/JCI66398. Epub 2013 Jun 3. J Clin Invest. 2013. PMID: 23722902 Free PMC article.
18 results