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The human fetal thymus generates invariant effector γδ T cells.
Tieppo P, Papadopoulou M, Gatti D, McGovern N, Chan JKY, Gosselin F, Goetgeluk G, Weening K, Ma L, Dauby N, Cogan A, Donner C, Ginhoux F, Vandekerckhove B, Vermijlen D. Tieppo P, et al. J Exp Med. 2020 Mar 2;217(3):jem.20190580. doi: 10.1084/jem.20190580. J Exp Med. 2020. PMID: 31816633 Free PMC article.
Broad Cytotoxic Targeting of Acute Myeloid Leukemia by Polyclonal Delta One T Cells.
Di Lorenzo B, Simões AE, Caiado F, Tieppo P, Correia DV, Carvalho T, da Silva MG, Déchanet-Merville J, Schumacher TN, Prinz I, Norell H, Ravens S, Vermijlen D, Silva-Santos B. Di Lorenzo B, et al. Among authors: tieppo p. Cancer Immunol Res. 2019 Apr;7(4):552-558. doi: 10.1158/2326-6066.CIR-18-0647. Epub 2019 Mar 20. Cancer Immunol Res. 2019. PMID: 30894378
Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities.
Van Caeneghem Y, De Munter S, Tieppo P, Goetgeluk G, Weening K, Verstichel G, Bonte S, Taghon T, Leclercq G, Kerre T, Debets R, Vermijlen D, Abken H, Vandekerckhove B. Van Caeneghem Y, et al. Among authors: tieppo p. Oncoimmunology. 2017 Jan 19;6(3):e1283460. doi: 10.1080/2162402X.2017.1283460. eCollection 2017. Oncoimmunology. 2017. PMID: 28405508 Free PMC article.