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Year Number of Results
1999 3
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5,318 results

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Page 1
Tigecycline antibacterial activity, clinical effectiveness, and mechanisms and epidemiology of resistance: narrative review.
Yaghoubi S, Zekiy AO, Krutova M, Gholami M, Kouhsari E, Sholeh M, Ghafouri Z, Maleki F. Yaghoubi S, et al. Eur J Clin Microbiol Infect Dis. 2022 Jul;41(7):1003-1022. doi: 10.1007/s10096-020-04121-1. Epub 2021 Jan 5. Eur J Clin Microbiol Infect Dis. 2022. PMID: 33403565 Free PMC article. Review.
New evidence also suggests the effectiveness of tigecycline for the treatment of severe Clostridioides difficile infections. Tigecycline showed in vitro susceptibility to Coxiella spp., Rickettsia spp., and multidrug-resistant Neisseria gonnorrhoeae strains which in …
New evidence also suggests the effectiveness of tigecycline for the treatment of severe Clostridioides difficile infections. Tigec …
Tigecycline-induced coagulopathy: a literature review.
Cui N, Cai H, Li Z, Lu Y, Wang G, Lu A. Cui N, et al. Int J Clin Pharm. 2019 Dec;41(6):1408-1413. doi: 10.1007/s11096-019-00912-5. Epub 2019 Nov 11. Int J Clin Pharm. 2019. PMID: 31713108 Review.
Coagulopathy is a lesser known side effect of tigecycline. Aim of the review We summarize the characteristics, possible mechanisms, and treatment of tigecycline-induced coagulopathy. ...There is no specific treatment for tigecycline-induced coagulopathy, but …
Coagulopathy is a lesser known side effect of tigecycline. Aim of the review We summarize the characteristics, possible mechanisms, a …
Emergence of plasmid-mediated high-level tigecycline resistance genes in animals and humans.
He T, Wang R, Liu D, Walsh TR, Zhang R, Lv Y, Ke Y, Ji Q, Wei R, Liu Z, Shen Y, Wang G, Sun L, Lei L, Lv Z, Li Y, Pang M, Wang L, Sun Q, Fu Y, Song H, Hao Y, Shen Z, Wang S, Chen G, Wu C, Shen J, Wang Y. He T, et al. Nat Microbiol. 2019 Sep;4(9):1450-1456. doi: 10.1038/s41564-019-0445-2. Epub 2019 May 27. Nat Microbiol. 2019. PMID: 31133751
Tigecycline is a last-resort antibiotic that is used to treat severe infections caused by extensively drug-resistant bacteria. tet(X) has been shown to encode a flavin-dependent monooxygenase that modifies tigecycline(1,2). ...Tet(X3) and Tet(X4) inactivate all tetr …
Tigecycline is a last-resort antibiotic that is used to treat severe infections caused by extensively drug-resistant bacteria. tet(X) …
Resistance evolution of hypervirulent carbapenem-resistant Klebsiella pneumoniae ST11 during treatment with tigecycline and polymyxin.
Jin X, Chen Q, Shen F, Jiang Y, Wu X, Hua X, Fu Y, Yu Y. Jin X, et al. Emerg Microbes Infect. 2021 Dec;10(1):1129-1136. doi: 10.1080/22221751.2021.1937327. Emerg Microbes Infect. 2021. PMID: 34074225 Free PMC article.
String and antimicrobial susceptibility tests identified seven hypermucoviscous strains and three tigecycline-resistant and four colistin-resistant strains. Galleria mellonella larvae infection model confirmed the hypervirulence. ...A novel frameshift mutation of lon was i …
String and antimicrobial susceptibility tests identified seven hypermucoviscous strains and three tigecycline-resistant and four coli …
Resistance mechanisms of tigecycline in Acinetobacter baumannii.
Sun C, Yu Y, Hua X. Sun C, et al. Front Cell Infect Microbiol. 2023 May 9;13:1141490. doi: 10.3389/fcimb.2023.1141490. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37228666 Free PMC article. Review.
Accordingly, there is a need to systematically investigate the mechanisms of tigecycline resistance in A. baumannii. Currently, the resistance mechanism of A. baumannii to tigecycline is complex and not completely clear. This article reviews the proposed resistance …
Accordingly, there is a need to systematically investigate the mechanisms of tigecycline resistance in A. baumannii. Currently, the r …
Plasmid-encoded tet(X) genes that confer high-level tigecycline resistance in Escherichia coli.
Sun J, Chen C, Cui CY, Zhang Y, Liu X, Cui ZH, Ma XY, Feng Y, Fang LX, Lian XL, Zhang RM, Tang YZ, Zhang KX, Liu HM, Zhuang ZH, Zhou SD, Lv JN, Du H, Huang B, Yu FY, Mathema B, Kreiswirth BN, Liao XP, Chen L, Liu YH. Sun J, et al. Nat Microbiol. 2019 Sep;4(9):1457-1464. doi: 10.1038/s41564-019-0496-4. Epub 2019 Jun 24. Nat Microbiol. 2019. PMID: 31235960 Free PMC article.
Tigecycline is one of the last-resort antibiotics to treat complicated infections caused by both multidrug-resistant Gram-negative and Gram-positive bacteria(1). ...Here, we report the emergence of the plasmid-mediated mobile tigecycline resistance mechanism Tet(X4) …
Tigecycline is one of the last-resort antibiotics to treat complicated infections caused by both multidrug-resistant Gram-negative an …
Update on prevalence and mechanisms of resistance to linezolid, tigecycline and daptomycin in enterococci in Europe: Towards a common nomenclature.
Bender JK, Cattoir V, Hegstad K, Sadowy E, Coque TM, Westh H, Hammerum AM, Schaffer K, Burns K, Murchan S, Novais C, Freitas AR, Peixe L, Del Grosso M, Pantosti A, Werner G. Bender JK, et al. Drug Resist Updat. 2018 Sep;40:25-39. doi: 10.1016/j.drup.2018.10.002. Epub 2018 Nov 2. Drug Resist Updat. 2018. PMID: 30447411 Free article. Review.
In vitro, most VRE remain susceptible to last-resort antibiotics such as linezolid, tigecycline and daptomycin. However, neither tigecycline nor linezolid act in a bactericidal manner, and daptomycin has proven activity only at high dosages licensed for treating ent …
In vitro, most VRE remain susceptible to last-resort antibiotics such as linezolid, tigecycline and daptomycin. However, neither t …
Population Pharmacokinetics of Tigecycline: A Systematic Review.
Zhou CC, Huang F, Zhang JM, Zhuang YG. Zhou CC, et al. Drug Des Devel Ther. 2022 Jun 17;16:1885-1896. doi: 10.2147/DDDT.S365512. eCollection 2022. Drug Des Devel Ther. 2022. PMID: 35747442 Free PMC article. Review.
Although tigecycline is widely used in clinical practice, its efficiency and optimal dosage regimens remain controversial. The purpose of this article was to help guide tigecycline dosing in different patient subpopulations through comparing the published population …
Although tigecycline is widely used in clinical practice, its efficiency and optimal dosage regimens remain controversial. The purpos …
Effectiveness and Safety of High Dose Tigecycline for the Treatment of Severe Infections: A Systematic Review and Meta-Analysis.
Zha L, Pan L, Guo J, French N, Villanueva EV, Tefsen B. Zha L, et al. Adv Ther. 2020 Mar;37(3):1049-1064. doi: 10.1007/s12325-020-01235-y. Epub 2020 Jan 31. Adv Ther. 2020. PMID: 32006240 Free PMC article.
BACKGROUND: Studies assessing the effect of high dose tigecycline on severe infections are limited and remain controversial. OBJECTIVES: To assess systematically the effectiveness and safety of high dose tigecycline in the treatment of severe infections. METHODS: Pu …
BACKGROUND: Studies assessing the effect of high dose tigecycline on severe infections are limited and remain controversial. OBJECTIV …
Acinetobacter baumannii: Pathogenesis, virulence factors, novel therapeutic options and mechanisms of resistance to antimicrobial agents with emphasis on tigecycline.
Dehbanipour R, Ghalavand Z. Dehbanipour R, et al. J Clin Pharm Ther. 2022 Nov;47(11):1875-1884. doi: 10.1111/jcpt.13787. Epub 2022 Oct 6. J Clin Pharm Ther. 2022. PMID: 36200470 Review.
Among therapeutic antibiotics, resistance to tigecycline as a last resort antibiotic has become a global concern. Several mechanisms are involved in tigecycline resistance, the most important of which is RND (Resistance-Nodulation-Division) family efflux pumps overe …
Among therapeutic antibiotics, resistance to tigecycline as a last resort antibiotic has become a global concern. Several mechanisms …
5,318 results