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Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.
Oppmann B, Lesley R, Blom B, Timans JC, Xu Y, Hunte B, Vega F, Yu N, Wang J, Singh K, Zonin F, Vaisberg E, Churakova T, Liu M, Gorman D, Wagner J, Zurawski S, Liu Y, Abrams JS, Moore KW, Rennick D, de Waal-Malefyt R, Hannum C, Bazan JF, Kastelein RA. Oppmann B, et al. Among authors: timans jc. Immunity. 2000 Nov;13(5):715-25. doi: 10.1016/s1074-7613(00)00070-4. Immunity. 2000. PMID: 11114383 Free article.
IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells.
Pflanz S, Timans JC, Cheung J, Rosales R, Kanzler H, Gilbert J, Hibbert L, Churakova T, Travis M, Vaisberg E, Blumenschein WM, Mattson JD, Wagner JL, To W, Zurawski S, McClanahan TK, Gorman DM, Bazan JF, de Waal Malefyt R, Rennick D, Kastelein RA. Pflanz S, et al. Among authors: timans jc. Immunity. 2002 Jun;16(6):779-90. doi: 10.1016/s1074-7613(02)00324-2. Immunity. 2002. PMID: 12121660 Free article.
A family of human receptors structurally related to Drosophila Toll.
Rock FL, Hardiman G, Timans JC, Kastelein RA, Bazan JF. Rock FL, et al. Among authors: timans jc. Proc Natl Acad Sci U S A. 1998 Jan 20;95(2):588-93. doi: 10.1073/pnas.95.2.588. Proc Natl Acad Sci U S A. 1998. PMID: 9435236 Free PMC article.
A newly defined interleukin-1?
Bazan JF, Timans JC, Kastelein RA. Bazan JF, et al. Among authors: timans jc. Nature. 1996 Feb 15;379(6566):591. doi: 10.1038/379591a0. Nature. 1996. PMID: 8628393 No abstract available.
12 results