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Developmental gene regulation in Aspergillus nidulans.
Timberlake WE. Timberlake WE. Dev Biol. 1980 Aug;78(2):497-510. doi: 10.1016/0012-1606(80)90349-8. Dev Biol. 1980. PMID: 6997115 No abstract available.
Developmental regulation of laccase levels in Aspergillus nidulans.
Law DJ, Timberlake WE. Law DJ, et al. J Bacteriol. 1980 Nov;144(2):509-17. doi: 10.1128/JB.144.2.509-517.1980. J Bacteriol. 1980. PMID: 7000747 Free PMC article.
We have investigated the mechanisms regulating expression of the gamma A gene of A. nidulans. Vegetative hyphae grown in submerged culture lacked detectable laccase enzyme activity and neither contained nor synthesized immunoprecipitable laccase protein. ...
We have investigated the mechanisms regulating expression of the gamma A gene of A. nidulans. Vegetative hyphae grown in submerged cu
The Aspergillus nidulans abaA gene encodes a transcriptional activator that acts as a genetic switch to control development.
Andrianopoulos A, Timberlake WE. Andrianopoulos A, et al. Mol Cell Biol. 1994 Apr;14(4):2503-15. doi: 10.1128/mcb.14.4.2503. Mol Cell Biol. 1994. PMID: 8139553 Free PMC article.
From these observations, we propose that the AbaA transcription factor establishes a novel set of feedback regulatory loops responsible for determination of conidiophore development....
From these observations, we propose that the AbaA transcription factor establishes a novel set of feedback regulatory loops responsib …
brlA is necessary and sufficient to direct conidiophore development in Aspergillus nidulans.
Adams TH, Boylan MT, Timberlake WE. Adams TH, et al. Cell. 1988 Jul 29;54(3):353-62. doi: 10.1016/0092-8674(88)90198-5. Cell. 1988. PMID: 3293800
We propose that BRLA is a nucleic acid-binding protein whose expression in vegetative cells is sufficient to induce sporulation through its role in regulating expression of conidiation-specific genes....
We propose that BRLA is a nucleic acid-binding protein whose expression in vegetative cells is sufficient to induce sporulation throu
Organization of a gene cluster expressed specifically in the asexual spores of A. nidulans.
Timberlake WE, Barnard EC. Timberlake WE, et al. Cell. 1981 Oct;26(1 Pt 1):29-37. doi: 10.1016/0092-8674(81)90030-1. Cell. 1981. PMID: 7034956
We have investigated the organization and regulation of a 13.3 kb region of the Aspergillus nidulans genome that is preferentially expressed during conidiophore development. ...
We have investigated the organization and regulation of a 13.3 kb region of the Aspergillus nidulans genome that is preferentially ex
Clustering of spore-specific genes in Aspergillus nidulans.
Orr WC, Timberlake WE. Orr WC, et al. Proc Natl Acad Sci U S A. 1982 Oct;79(19):5976-80. doi: 10.1073/pnas.79.19.5976. Proc Natl Acad Sci U S A. 1982. PMID: 6764535 Free PMC article.
We have investigated the chromosomal organization of genes that are expressed specifically in the asexual spores (conidia) of the Ascomycete fungus Aspergillus nidulans, using two experimental approaches. ...
We have investigated the chromosomal organization of genes that are expressed specifically in the asexual spores (conidia) of the Asc
catA, a new Aspergillus nidulans gene encoding a developmentally regulated catalase.
Navarro RE, Stringer MA, Hansberg W, Timberlake WE, Aguirre J. Navarro RE, et al. Among authors: timberlake we. Curr Genet. 1996 Mar;29(4):352-9. Curr Genet. 1996. PMID: 8598056
Structure and regulated expression of the SpoC1 gene cluster from Aspergillus nidulans.
Gwynne DI, Miller BL, Miller KY, Timberlake WE. Gwynne DI, et al. J Mol Biol. 1984 Nov 25;180(1):91-109. doi: 10.1016/0022-2836(84)90432-7. J Mol Biol. 1984. PMID: 6392570
We have previously described the organization of a 13.3 kb region of the Aspergillus nidulans genome, designated SpoC1, coding for multiple poly(A)+ RNAs that accumulate in asexual spores but not in somatic cells. We have determined the limits of the SpoC1 gene clus
We have previously described the organization of a 13.3 kb region of the Aspergillus nidulans genome, designated SpoC1, coding for mu
Developmental regulation of the Aspergillus nidulans trpC gene.
Yelton MM, Hamer JE, de Souza ER, Mullaney EJ, Timberlake WE. Yelton MM, et al. Proc Natl Acad Sci U S A. 1983 Dec;80(24):7576-80. doi: 10.1073/pnas.80.24.7576. Proc Natl Acad Sci U S A. 1983. PMID: 6324178 Free PMC article.
We determined that a 1.8-kilobase DNA fragment was minimally required for complementation. The fragment hybridized with two poly(A)+ RNAs, 3.0 and 3.2 kilobases in length. We infer that these transcripts are Aspergillus trpC mRNAs and that the entire Aspergillus trp
We determined that a 1.8-kilobase DNA fragment was minimally required for complementation. The fragment hybridized with two poly(A)+
Position-dependent and -independent mechanisms regulate cell-specific expression of the SpoC1 gene cluster of Aspergillus nidulans.
Miller BL, Miller KY, Roberti KA, Timberlake WE. Miller BL, et al. Mol Cell Biol. 1987 Jan;7(1):427-34. doi: 10.1128/mcb.7.1.427. Mol Cell Biol. 1987. PMID: 3550422 Free PMC article.
We investigated the effects of altered chromosomal position on expression of a gene from the conidiation-specific SpoC1 gene cluster. ...We propose that the two types of regulation act together to produce the major differences in transcript levels observed in hyphae
We investigated the effects of altered chromosomal position on expression of a gene from the conidiation-specific SpoC1 gene cluster.
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