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The Genetic Epidemiology of Pediatric Pulmonary Arterial Hypertension.
Haarman MG, Kerstjens-Frederikse WS, Vissia-Kazemier TR, Breeman KTN, Timens W, Vos YJ, Roofthooft MTR, Hillege HL, Berger RMF. Haarman MG, et al. Among authors: Timens W. J Pediatr. 2020 Jun 2:S0022-3476(20)30689-2. doi: 10.1016/j.jpeds.2020.05.051. Online ahead of print. J Pediatr. 2020. PMID: 32502478
Link between increased cellular senescence and extracellular matrix changes in COPD.
Woldhuis RR, de Vries M, Timens W, van den Berge M, Demaria M, Oliver BGG, Heijink IH, Brandsma CA. Woldhuis RR, et al. Among authors: Timens W. Am J Physiol Lung Cell Mol Physiol. 2020 May 27. doi: 10.1152/ajplung.00028.2020. Online ahead of print. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32460521
Epithelial-interleukin-1 inhibits collagen formation by airway fibroblasts: Implications for asthma.
Osei ET, B Mostaço-Guidolin L, Hsieh A, Warner SM, Al-Fouadi M, Wang M, Cole DJ, Maksym GN, S Hallstrand T, Timens W, Brandsma CA, Heijink IH, Hackett TL. Osei ET, et al. Among authors: Timens W. Sci Rep. 2020 May 26;10(1):8721. doi: 10.1038/s41598-020-65567-z. Sci Rep. 2020. PMID: 32457454 Free PMC article.
Angiotensin-converting enzyme-2 (ACE2), SARS-CoV-2 and pathophysiology of coronavirus disease 2019 (COVID-19).
Bourgonje AR, Abdulle AE, Timens W, Hillebrands JL, Navis GJ, Gordijn SJ, Bolling MC, Dijkstra G, Voors AA, Osterhaus ADME, van der Voort PHJ, Mulder DJ, van Goor H. Bourgonje AR, et al. Among authors: Timens W. J Pathol. 2020 May 17. doi: 10.1002/path.5471. Online ahead of print. J Pathol. 2020. PMID: 32418199 Review.
SARS-CoV-2 receptor ACE2 gene expression and RAAS inhibitors.
Milne S, Yang CX, Timens W, Bossé Y, Sin DD. Milne S, et al. Among authors: Timens W. Lancet Respir Med. 2020 May 13. doi: 10.1016/S2213-2600(20)30224-1. Online ahead of print. Lancet Respir Med. 2020. PMID: 32411576 Free PMC article. No abstract available.
Protein-altering germline mutations implicate novel genes related to lung cancer development.
Ji X, Mukherjee S, Landi MT, Bosse Y, Joubert P, Zhu D, Gorlov I, Xiao X, Han Y, Gorlova O, Hung RJ, Brhane Y, Carreras-Torres R, Christiani DC, Caporaso N, Johansson M, Liu G, Bojesen SE, Le Marchand L, Albanes D, Bickeböller H, Aldrich MC, Bush WS, Tardon A, Rennert G, Chen C, Byun J, Dragnev KH, Field JK, Kiemeney LF, Lazarus P, Zienolddiny S, Lam S, Schabath MB, Andrew AS, Bertazzi PA, Pesatori AC, Diao N, Su L, Song L, Zhang R, Leighl N, Johansen JS, Mellemgaard A, Saliba W, Haiman C, Wilkens L, Fernandez-Somoano A, Fernandez-Tardon G, Heijden EHFMV, Kim JH, Davies MPA, Marcus MW, Brunnström H, Manjer J, Melander O, Muller DC, Overvad K, Trichopoulou A, Tumino R, Goodman GE, Cox A, Taylor F, Woll P, Wichmann E, Muley T, Risch A, Rosenberger A, Grankvist K, Johansson M, Shepherd F, Tsao MS, Arnold SM, Haura EB, Bolca C, Holcatova I, Janout V, Kontic M, Lissowska J, Mukeria A, Ognjanovic S, Orlowski TM, Scelo G, Swiatkowska B, Zaridze D, Bakke P, Skaug V, Butler LM, Offit K, Srinivasan P, Bandlamudi C, Hellmann MD, Solit DB, Robson ME, Rudin CM, Stadler ZK, Taylor BS, Berger MF, Houlston R, McLaughlin J, Stevens V, Nickle DC, Obeidat M, Timens W, Artigas MS, Shete S, Brenner H, Chanock S, Brennan P, McKay JD, Amos CI. Ji X, et al. Among authors: Timens W. Nat Commun. 2020 May 11;11(1):2220. doi: 10.1038/s41467-020-15905-6. Nat Commun. 2020. PMID: 32393777 Free PMC article.
Cholinergic neuroplasticity in asthma driven by TrkB signaling.
Dragunas G, Woest ME, Nijboer S, Bos ST, van Asselt J, de Groot AP, Vohlídalová E, Vermeulen CJ, Ditz B, Vonk JM, Koppelman GH, van den Berge M, Ten Hacken NHT, Timens W, Munhoz CD, Prakash YS, Gosens R, Kistemaker LEM. Dragunas G, et al. Among authors: Timens W. FASEB J. 2020 Apr 11. doi: 10.1096/fj.202000170R. Online ahead of print. FASEB J. 2020. PMID: 32277855
Detection of Circulating Tumor Cells in the Diagnostic Leukapheresis Product of Non-Small-Cell Lung Cancer Patients Comparing CellSearch® and ISET.
Tamminga M, Andree KC, Hiltermann TJN, Jayat M, Schuuring E, van den Bos H, Spierings DCJ, Lansdorp PM, Timens W, Terstappen LWMM, Groen HJM. Tamminga M, et al. Among authors: Timens W. Cancers (Basel). 2020 Apr 7;12(4):896. doi: 10.3390/cancers12040896. Cancers (Basel). 2020. PMID: 32272669 Free PMC article.
Human lung extracellular matrix hydrogels resemble the stiffness and viscoelasticity of native lung tissue.
de Hilster RHJ, Sharma PK, Jonker MR, White ES, Gercama EA, Roobeek M, Timens W, Harmsen MC, Hylkema MN, Burgess JK. de Hilster RHJ, et al. Among authors: Timens W. Am J Physiol Lung Cell Mol Physiol. 2020 Apr 1;318(4):L698-L704. doi: 10.1152/ajplung.00451.2019. Epub 2020 Feb 12. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32048864 Free PMC article.
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