Timm J - Search Results

1

Early Transcriptional Divergence Marks Virus-Specific Primary Human CD8⁺ T Cells in Chronic versus Acute Infection.

Wolski D, Foote PK, Chen DY, Lewis-Ximenez LL, Fauvelle C, Aneja J, Walker A, Tonnerre P, Torres-Cornejo A, Kvistad D, Imam S, Waring MT, Tully DC, Allen TM, Chung RT, Timm J, Haining WN, Kim AY, Baumert TF, Lauer GM. Wolski D, et al. Among authors: timm j. Immunity. 2017 Oct 17;47(4):648-663.e8. doi: 10.1016/j.immuni.2017.09.006. Immunity. 2017. PMID: 29045899 Free PMC article.

2

Virological and immunological determinants of intrahepatic virus-specific CD8+ T-cell failure in chronic hepatitis C virus infection.

Neumann-Haefelin C, Timm J, Spangenberg HC, Wischniowski N, Nazarova N, Kersting N, Roggendorf M, Allen TM, Blum HE, Thimme R. Neumann-Haefelin C, et al. Among authors: timm j. Hepatology. 2008 Jun;47(6):1824-36. doi: 10.1002/hep.22242. Hepatology. 2008. PMID: 18454507

3

Protective effect of human leukocyte antigen B27 in hepatitis C virus infection requires the presence of a genotype-specific immunodominant CD8+ T-cell epitope.

Neumann-Haefelin C, Timm J, Schmidt J, Kersting N, Fitzmaurice K, Oniangue-Ndza C, Kemper MN, Humphreys I, McKiernan S, Kelleher D, Lohmann V, Bowness P, Huzly D, Rosen HR, Kim AY, Lauer GM, Allen TM, Barnes E, Roggendorf M, Blum HE, Thimme R. Neumann-Haefelin C, et al. Among authors: timm j. Hepatology. 2010 Jan;51(1):54-62. doi: 10.1002/hep.23275. Hepatology. 2010. PMID: 20034048 Free PMC article.

4

Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation.

Bengsch B, Seigel B, Ruhl M, Timm J, Kuntz M, Blum HE, Pircher H, Thimme R. Bengsch B, et al. Among authors: timm j. PLoS Pathog. 2010 Jun 10;6(6):e1000947. doi: 10.1371/journal.ppat.1000947. PLoS Pathog. 2010. PMID: 20548953 Free PMC article.

5

Escape from a dominant HLA-B*15-restricted CD8+ T cell response against hepatitis C virus requires compensatory mutations outside the epitope.

Ruhl M, Chhatwal P, Strathmann H, Kuntzen T, Bankwitz D, Skibbe K, Walker A, Heinemann FM, Horn PA, Allen TM, Hoffmann D, Pietschmann T, Timm J. Ruhl M, et al. Among authors: timm j. J Virol. 2012 Jan;86(2):991-1000. doi: 10.1128/JVI.05603-11. Epub 2011 Nov 9. J Virol. 2012. PMID: 22072759 Free PMC article.

6

Susceptibility to chronic hepatitis C virus infection is influenced by sequence differences in immunodominant CD8+ T cell epitopes.

Ziegler S, Ruhl M, Tenckhoff H, Wiese M, Heinemann FM, Horn PA, Spengler U, Neumann-Haefelin C, Nattermann J, Timm J; East-German HCV Study Group. Ziegler S, et al. Among authors: timm j. J Hepatol. 2013 Jan;58(1):24-30. doi: 10.1016/j.jhep.2012.08.016. Epub 2012 Aug 25. J Hepatol. 2013. PMID: 22925811

7

HLA-B*27 subtype specificity determines targeting and viral evolution of a hepatitis C virus-specific CD8+ T cell epitope.

Nitschke K, Barriga A, Schmidt J, Timm J, Viazov S, Kuntzen T, Kim AY, Lauer GM, Allen TM, Gaudieri S, Rauch A, Lange CM, Sarrazin C, Eiermann T, Sidney J, Sette A, Thimme R, López D, Neumann-Haefelin C. Nitschke K, et al. Among authors: timm j. J Hepatol. 2014 Jan;60(1):22-9. doi: 10.1016/j.jhep.2013.08.009. Epub 2013 Aug 23. J Hepatol. 2014. PMID: 23978718 Free PMC article.

8

Impact of sequence variation in a dominant HLA-A*02-restricted epitope in hepatitis C virus on priming and cross-reactivity of CD8+ T cells.

Ziegler S, Skibbe K, Walker A, Ke X, Heinemann FM, Heinold A, Mok JY, van Esch WJ, Yang D, Wölfl M, Timm J. Ziegler S, et al. Among authors: timm j. J Virol. 2014 Oct;88(19):11080-90. doi: 10.1128/JVI.01590-14. Epub 2014 Jul 9. J Virol. 2014. PMID: 25008925 Free PMC article.

9

Acute hepatitis C virus infection induces anti-host cell receptor antibodies with virus-neutralizing properties.

Tawar RG, Colpitts CC, Timm J, Fehm T, Roggendorf M, Meisel H, Meyer N, Habersetzer F, Cosset FL, Berg T, Zeisel MB, Baumert TF. Tawar RG, et al. Among authors: timm j. Hepatology. 2015 Sep;62(3):726-36. doi: 10.1002/hep.27906. Epub 2015 Jul 28. Hepatology. 2015. PMID: 26010076

10

Natural prevalence of resistance-associated variants in hepatitis C virus NS5A in genotype 3a-infected people who inject drugs in Germany.

Walker A, Siemann H, Groten S, Ross RS, Scherbaum N, Timm J. Walker A, et al. Among authors: timm j. J Clin Virol. 2015 Sep;70:43-45. doi: 10.1016/j.jcv.2015.07.008. Epub 2015 Jul 8. J Clin Virol. 2015. PMID: 26305818

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