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Cannabinoid-1 (CB1) receptors regulate colonic propulsion by acting at motor neurons within the ascending motor pathways in mouse colon.
Sibaev A, Yüce B, Kemmer M, Van Nassauw L, Broedl U, Allescher HD, Göke B, Timmermans JP, Storr M. Sibaev A, et al. Among authors: timmermans jp. Am J Physiol Gastrointest Liver Physiol. 2009 Jan;296(1):G119-28. doi: 10.1152/ajpgi.90274.2008. Epub 2008 Nov 25. Am J Physiol Gastrointest Liver Physiol. 2009. PMID: 19033531 Free article.
FABP4 blocker attenuates colonic hypomotility and modulates white adipose tissue-derived hormone levels in mouse models mimicking constipation-predominant IBS.
Mosińska P, Jacenik D, Sałaga M, Wasilewski A, Cygankiewicz A, Sibaev A, Mokrowiecka A, Małecka-Panas E, Pintelon I, Storr M, Timmermans JP, Krajewska WM, Fichna J. Mosińska P, et al. Among authors: timmermans jp. Neurogastroenterol Motil. 2018 May;30(5):e13272. doi: 10.1111/nmo.13272. Epub 2017 Dec 20. Neurogastroenterol Motil. 2018. PMID: 29266569
360 results