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The importance of correct assignment of CYP2B6 genetic variants with respect to cyclophosphamide metabolizer status.
Helsby N, Tingle M. Helsby N, et al. Among authors: tingle m. Am J Hematol. 2011 Apr;86(4):383-4; author reply 384. doi: 10.1002/ajh.21987. Am J Hematol. 2011. PMID: 21442647 No abstract available.
Which CYP2B6 variants have functional consequences for cyclophosphamide bioactivation?
Helsby NA, Tingle MD. Helsby NA, et al. Drug Metab Dispos. 2012 Mar;40(3):635-7. doi: 10.1124/dmd.111.043646. Epub 2011 Dec 8. Drug Metab Dispos. 2012. PMID: 22159699 No abstract available.
The combined impact of CYP2C19 and CYP2B6 pharmacogenetics on cyclophosphamide bioactivation.
Helsby NA, Hui CY, Goldthorpe MA, Coller JK, Soh MC, Gow PJ, De Zoysa JZ, Tingle MD. Helsby NA, et al. Br J Clin Pharmacol. 2010 Dec;70(6):844-53. doi: 10.1111/j.1365-2125.2010.03789.x. Br J Clin Pharmacol. 2010. PMID: 21175440 Free PMC article.
In vivo metabolism of norbormide in rats and mice.
Ravindran S, Hopkins B, Bova S, Tingle M. Ravindran S, et al. Among authors: tingle m. Environ Toxicol Pharmacol. 2009 Jul;28(1):147-51. doi: 10.1016/j.etap.2009.03.013. Epub 2009 Apr 8. Environ Toxicol Pharmacol. 2009. PMID: 21783995
In vitro metabolism of norbormide in rat, mouse and guinea pig liver preparations.
Ravindran S, Hopkins B, Bova S, Rennison D, Brimble M, Tingle M. Ravindran S, et al. Among authors: tingle m. Environ Toxicol Pharmacol. 2009 Jan;27(1):144-8. doi: 10.1016/j.etap.2008.09.007. Epub 2008 Oct 19. Environ Toxicol Pharmacol. 2009. PMID: 21783932
Party pills and drug-drug interactions.
Murphy M, Antia U, Chang HY, Han JY, Ibrahim U, Tingle M, Russell B. Murphy M, et al. Among authors: tingle m. N Z Med J. 2009 Apr 24;122(1293):3564. N Z Med J. 2009. PMID: 19448787
Metabolism of thalidomide in liver microsomes of mice, rabbits, and humans.
Lu J, Helsby N, Palmer BD, Tingle M, Baguley BC, Kestell P, Ching LM. Lu J, et al. Among authors: tingle m. J Pharmacol Exp Ther. 2004 Aug;310(2):571-7. doi: 10.1124/jpet.104.067793. Epub 2004 Apr 9. J Pharmacol Exp Ther. 2004. PMID: 15075384
Indirect regulation of CYP2C19 gene expression via DNA methylation.
Burns KE, Shepherd P, Finlay G, Tingle MD, Helsby NA. Burns KE, et al. Xenobiotica. 2018 Aug;48(8):781-792. doi: 10.1080/00498254.2017.1372648. Epub 2017 Sep 19. Xenobiotica. 2018. PMID: 28840784
Species differences in the metabolism of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid in vitro: implications for prediction of metabolic interactions in vivo.
Zhou SF, Tingle MD, Kestell P, Paxton JW. Zhou SF, et al. Among authors: tingle md. Xenobiotica. 2002 Feb;32(2):87-107. doi: 10.1080/00498250110092423. Xenobiotica. 2002. PMID: 11868972
Can in vitro drug metabolism studies with human tissue replace in vivo animal studies?
Tingle MD, Helsby NA. Tingle MD, et al. Environ Toxicol Pharmacol. 2006 Feb;21(2):184-90. doi: 10.1016/j.etap.2005.07.008. Epub 2005 Aug 2. Environ Toxicol Pharmacol. 2006. PMID: 21783656
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