Tingle MD - Search Results

1

N-Hydroxylation of dapsone by multiple enzymes of cytochrome P450: implications for inhibition of haemotoxicity.

Gill HJ, Tingle MD, Park BK. Gill HJ, et al. Among authors: tingle md. Br J Clin Pharmacol. 1995 Dec;40(6):531-8. doi: 10.1111/j.1365-2125.1995.tb05797.x. Br J Clin Pharmacol. 1995. PMID: 8703658 Free PMC article.

2

Structural basis for the haemotoxicity of dapsone: the importance of the sulphonyl group.

Mahmud R, Tingle MD, Maggs JL, Cronin MT, Dearden JC, Park BK. Mahmud R, et al. Among authors: tingle md. Toxicology. 1997 Feb 14;117(1):1-11. doi: 10.1016/s0300-483x(96)03548-2. Toxicology. 1997. PMID: 9020194

3

Intracellular glutathione in the peripheral blood cells of HIV-infected patients: failure to show a deficiency.

Pirmohamed M, Williams D, Tingle MD, Barry M, Khoo SH, O'Mahony C, Wilkins EG, Breckenridge AM, Park BK. Pirmohamed M, et al. Among authors: tingle md. AIDS. 1996 May;10(5):501-7. doi: 10.1097/00002030-199605000-00008. AIDS. 1996. PMID: 8724041

4

Cimetidine improves the therapeutic/toxic ratio of dapsone in patients on chronic dapsone therapy.

Rhodes LE, Tingle MD, Park BK, Chu P, Verbov JL, Friedmann PS. Rhodes LE, et al. Among authors: tingle md. Br J Dermatol. 1995 Feb;132(2):257-62. doi: 10.1111/j.1365-2133.1995.tb05022.x. Br J Dermatol. 1995. PMID: 7888363

5

The use of a three compartment in vitro model to investigate the role of hepatic drug metabolism in drug-induced blood dyscrasias.

Tingle MD, Park BK. Tingle MD, et al. Br J Clin Pharmacol. 1993 Jul;36(1):31-8. doi: 10.1111/j.1365-2125.1993.tb05888.x. Br J Clin Pharmacol. 1993. PMID: 8373710 Free PMC article.

6

Evaluation of the generation of genotoxic and cytotoxic metabolites of benzo[a]pyrene, aflatoxin B1, naphthalene and tamoxifen using human liver microsomes and human lymphocytes.

Wilson AS, Tingle MD, Kelly MD, Park BK. Wilson AS, et al. Among authors: tingle md. Hum Exp Toxicol. 1995 Jun;14(6):507-15. doi: 10.1177/096032719501400608. Hum Exp Toxicol. 1995. PMID: 8519528

7

The effect of 2,2'-substitution on the metabolism and toxicity of dapsone in vitro and in vivo.

Tingle MD, Mahmud R, Maggs JL, Hawley S, Coleman MD, Ward SA, Park BK. Tingle MD, et al. Environ Toxicol Pharmacol. 1998 Mar;5(2):145-53. doi: 10.1016/s1382-6689(97)10070-9. Environ Toxicol Pharmacol. 1998. PMID: 21781861

8

Bioactivation and bioinactivation of drugs and drug metabolites: Relevance to adverse drug reactions.

Park BK, Pirmohamed M, Tingle MD, Madden S, Kitteringham NR. Park BK, et al. Among authors: tingle md. Toxicol In Vitro. 1994 Aug;8(4):613-21. doi: 10.1016/0887-2333(94)90029-9. Toxicol In Vitro. 1994. PMID: 20692973

9

Comparison of the metabolism and toxicity of dapsone in rat, mouse and man.

Tingle MD, Mahmud R, Maggs JL, Pirmohamed M, Park BK. Tingle MD, et al. J Pharmacol Exp Ther. 1997 Nov;283(2):817-23. J Pharmacol Exp Ther. 1997. PMID: 9353403

10

Bioactivation and inactivation of aflatoxin B1 by human, mouse and rat liver preparations: effect on SCE in human mononuclear leucocytes.

Wilson AS, Williams DP, Davis CD, Tingle MD, Park BK. Wilson AS, et al. Among authors: tingle md. Mutat Res. 1997 Feb 3;373(2):257-64. doi: 10.1016/s0027-5107(96)00205-9. Mutat Res. 1997. PMID: 9042408

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