Tjalkens RB - Search Results

1

Nuclear receptor 4A (NR4A) family - orphans no more.

Safe S, Jin UH, Morpurgo B, Abudayyeh A, Singh M, Tjalkens RB. Safe S, et al. Among authors: tjalkens rb. J Steroid Biochem Mol Biol. 2016 Mar;157:48-60. doi: 10.1016/j.jsbmb.2015.04.016. Epub 2015 Apr 23. J Steroid Biochem Mol Biol. 2016. PMID: 25917081 Free PMC article.

2

The peroxisome proliferator-activated receptor-gamma agonist 1,1-bis(3'-indolyl)-1-(p-trifluoromethylphenyl)methane suppresses manganese-induced production of nitric oxide in astrocytes and inhibits apoptosis in cocultured PC12 cells.

Tjalkens RB, Liu X, Mohl B, Wright T, Moreno JA, Carbone DL, Safe S. Tjalkens RB, et al. J Neurosci Res. 2008 Feb 15;86(3):618-29. doi: 10.1002/jnr.21524. J Neurosci Res. 2008. PMID: 18041089

3

Suppression of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced nitric-oxide synthase 2 expression in astrocytes by a novel diindolylmethane analog protects striatal neurons against apoptosis.

Carbone DL, Popichak KA, Moreno JA, Safe S, Tjalkens RB. Carbone DL, et al. Among authors: tjalkens rb. Mol Pharmacol. 2009 Jan;75(1):35-43. doi: 10.1124/mol.108.050781. Epub 2008 Oct 7. Mol Pharmacol. 2009. PMID: 18840677 Free PMC article.

4

Toxicological and pathophysiological roles of reactive oxygen and nitrogen species.

Roberts RA, Smith RA, Safe S, Szabo C, Tjalkens RB, Robertson FM. Roberts RA, et al. Among authors: tjalkens rb. Toxicology. 2010 Oct 9;276(2):85-94. doi: 10.1016/j.tox.2010.07.009. Epub 2010 Jul 17. Toxicology. 2010. PMID: 20643181 Free PMC article. Review.

5

Neuroprotective efficacy and pharmacokinetic behavior of novel anti-inflammatory para-phenyl substituted diindolylmethanes in a mouse model of Parkinson's disease.

De Miranda BR, Miller JA, Hansen RJ, Lunghofer PJ, Safe S, Gustafson DL, Colagiovanni D, Tjalkens RB. De Miranda BR, et al. Among authors: tjalkens rb. J Pharmacol Exp Ther. 2013 Apr;345(1):125-38. doi: 10.1124/jpet.112.201558. Epub 2013 Jan 14. J Pharmacol Exp Ther. 2013. PMID: 23318470 Free PMC article.

6

Diindolylmethane analogs bind NR4A1 and are NR4A1 antagonists in colon cancer cells.

Lee SO, Li X, Hedrick E, Jin UH, Tjalkens RB, Backos DS, Li L, Zhang Y, Wu Q, Safe S. Lee SO, et al. Among authors: tjalkens rb. Mol Endocrinol. 2014 Oct;28(10):1729-39. doi: 10.1210/me.2014-1102. Epub 2014 Aug 6. Mol Endocrinol. 2014. PMID: 25099012 Free PMC article.

7

Novel para-phenyl substituted diindolylmethanes protect against MPTP neurotoxicity and suppress glial activation in a mouse model of Parkinson's disease.

De Miranda BR, Popichak KA, Hammond SL, Miller JA, Safe S, Tjalkens RB. De Miranda BR, et al. Among authors: tjalkens rb. Toxicol Sci. 2015 Feb;143(2):360-73. doi: 10.1093/toxsci/kfu236. Epub 2014 Nov 17. Toxicol Sci. 2015. PMID: 25406165 Free PMC article.

8

The Nurr1 Activator 1,1-Bis(3'-Indolyl)-1-(p-Chlorophenyl)Methane Blocks Inflammatory Gene Expression in BV-2 Microglial Cells by Inhibiting Nuclear Factor κB.

De Miranda BR, Popichak KA, Hammond SL, Jorgensen BA, Phillips AT, Safe S, Tjalkens RB. De Miranda BR, et al. Among authors: tjalkens rb. Mol Pharmacol. 2015 Jun;87(6):1021-34. doi: 10.1124/mol.114.095398. Epub 2015 Apr 9. Mol Pharmacol. 2015. PMID: 25858541 Free PMC article.

9

A novel synthetic activator of Nurr1 induces dopaminergic gene expression and protects against 6-hydroxydopamine neurotoxicity in vitro.

Hammond SL, Safe S, Tjalkens RB. Hammond SL, et al. Among authors: tjalkens rb. Neurosci Lett. 2015 Oct 21;607:83-89. doi: 10.1016/j.neulet.2015.09.015. Epub 2015 Sep 14. Neurosci Lett. 2015. PMID: 26383113 Free PMC article.

10

The Nurr1 Ligand,1,1-bis(3'-Indolyl)-1-(p-Chlorophenyl)Methane, Modulates Glial Reactivity and Is Neuroprotective in MPTP-Induced Parkinsonism.

Hammond SL, Popichak KA, Li X, Hunt LG, Richman EH, Damale PU, Chong EKP, Backos DS, Safe S, Tjalkens RB. Hammond SL, et al. Among authors: tjalkens rb. J Pharmacol Exp Ther. 2018 Jun;365(3):636-651. doi: 10.1124/jpet.117.246389. Epub 2018 Apr 6. J Pharmacol Exp Ther. 2018. PMID: 29626009 Free PMC article.

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