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Placental growth factor and its receptor, vascular endothelial growth factor receptor-1: novel targets for stimulation of ischemic tissue revascularization and inhibition of angiogenic and inflammatory disorders.
Autiero M, Luttun A, Tjwa M, Carmeliet P. Autiero M, et al. J Thromb Haemost. 2003 Jul;1(7):1356-70. doi: 10.1046/j.1538-7836.2003.00263.x. J Thromb Haemost. 2003. PMID: 12871269 Review.
The role of CD154 in haematopoietic development.
Seijkens T, Engel D, Tjwa M, Lutgens E. Seijkens T, et al. Thromb Haemost. 2010 Oct;104(4):693-701. doi: 10.1160/TH10-03-0174. Epub 2010 Aug 5. Thromb Haemost. 2010. PMID: 20694278 Review.
Inactivation of Smad5 in endothelial cells and smooth muscle cells demonstrates that Smad5 is required for cardiac homeostasis.
Umans L, Cox L, Tjwa M, Bito V, Vermeire L, Laperre K, Sipido K, Moons L, Huylebroeck D, Zwijsen A. Umans L, et al. Am J Pathol. 2007 May;170(5):1460-72. doi: 10.2353/ajpath.2007.060839. Am J Pathol. 2007. PMID: 17456754 Free PMC article.
Novel role for vascular endothelial growth factor (VEGF) receptor-1 and its ligand VEGF-B in motor neuron degeneration.
Poesen K, Lambrechts D, Van Damme P, Dhondt J, Bender F, Frank N, Bogaert E, Claes B, Heylen L, Verheyen A, Raes K, Tjwa M, Eriksson U, Shibuya M, Nuydens R, Van Den Bosch L, Meert T, D'Hooge R, Sendtner M, Robberecht W, Carmeliet P. Poesen K, et al. J Neurosci. 2008 Oct 15;28(42):10451-9. doi: 10.1523/JNEUROSCI.1092-08.2008. J Neurosci. 2008. PMID: 18923022 Free PMC article.
Reevaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium.
Li X, Tjwa M, Van Hove I, Enholm B, Neven E, Paavonen K, Jeltsch M, Juan TD, Sievers RE, Chorianopoulos E, Wada H, Vanwildemeersch M, Noel A, Foidart JM, Springer ML, von Degenfeld G, Dewerchin M, Blau HM, Alitalo K, Eriksson U, Carmeliet P, Moons L. Li X, et al. Arterioscler Thromb Vasc Biol. 2008 Sep;28(9):1614-20. doi: 10.1161/ATVBAHA.107.158725. Epub 2008 May 29. Arterioscler Thromb Vasc Biol. 2008. PMID: 18511699 Free PMC article.
A surrogate marker to monitor angiogenesis at last.
Schneider M, Tjwa M, Carmeliet P. Schneider M, et al. Cancer Cell. 2005 Jan;7(1):3-4. doi: 10.1016/j.ccr.2004.12.014. Cancer Cell. 2005. PMID: 15652744
Revascularization of ischemic tissues by PDGF-CC via effects on endothelial cells and their progenitors.
Li X, Tjwa M, Moons L, Fons P, Noel A, Ny A, Zhou JM, Lennartsson J, Li H, Luttun A, Pontén A, Devy L, Bouché A, Oh H, Manderveld A, Blacher S, Communi D, Savi P, Bono F, Dewerchin M, Foidart JM, Autiero M, Herbert JM, Collen D, Heldin CH, Eriksson U, Carmeliet P. Li X, et al. J Clin Invest. 2005 Jan;115(1):118-27. doi: 10.1172/JCI19189. J Clin Invest. 2005. PMID: 15630451 Free PMC article.
Genetic dissection of tumor angiogenesis: are PlGF and VEGFR-1 novel anti-cancer targets?
Luttun A, Autiero M, Tjwa M, Carmeliet P. Luttun A, et al. Biochim Biophys Acta. 2004 Mar 4;1654(1):79-94. doi: 10.1016/j.bbcan.2003.09.002. Biochim Biophys Acta. 2004. PMID: 14984769 Review.
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